| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 77,981,253 | 81,020,390 | +3,039,137 | 0.11 | 0.12 | +0.01 | buy |
| BlackRock, Inc. | 44,254,260 | 48,236,091 | +3,981,831 | 0.02 | 0.03 | +0.00 | buy |
| MORGAN STANLEY | 51,828,325 | 42,592,905 | -9,235,420 | 0.09 | 0.08 | -0.01 | sell |
| QVT Financial LP | 25,161,237 | 23,723,074 | -1,438,163 | 55.05 | 53.73 | -1.32 | sell |
| GOLDMAN SACHS GROUP INC | 11,111,591 | 18,556,458 | +7,444,867 | 0.04 | 0.07 | +0.03 | buy |
| STATE STREET CORP | 16,186,613 | 17,795,975 | +1,609,362 | 0.02 | 0.02 | +0.00 | buy |
| UBS Group AG | 22,619,472 | 17,466,641 | -5,152,831 | 0.11 | 0.10 | -0.01 | sell |
| FARALLON CAPITAL MANAGEMENT LLC | 9,675,000 | 14,309,000 | +4,634,000 | 1.59 | 2.96 | +1.38 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 10,182,477 | 11,674,380 | +1,491,903 | 0.02 | 0.02 | +0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 12,794,097 | 10,349,328 | -2,444,769 | 0.55 | 0.51 | -0.03 | sell |
| Two Seas Capital LP | 9,328,291 | 8,475,356 | -852,935 | 11.93 | 11.45 | -0.48 | sell |
| Assenagon Asset Management S.A. | 7,076,488 | 8,362,952 | +1,286,464 | 0.31 | 0.38 | +0.07 | buy |
| PERCEPTIVE ADVISORS LLC | 8,285,461 | 8,085,461 | -200,000 | 4.53 | 4.44 | -0.09 | sell |
| Patient Square Capital LP | 8,166,047 | 8,020,928 | -145,119 | 40.13 | 43.97 | +3.84 | sell |
| Invesco Ltd. | 6,439,145 | 7,531,192 | +1,092,047 | 0.02 | 0.02 | -0.00 | buy |
| Darwin Global Management, Ltd. | 6,797,300 | 6,747,300 | -50,000 | 4.76 | 6.23 | +1.47 | sell |
| AQR CAPITAL MANAGEMENT LLC | 5,946,858 | 6,633,560 | +686,702 | 0.07 | 0.08 | +0.01 | buy |
| VIKING GLOBAL INVESTORS LP | 6,652,448 | 6,271,467 | -380,981 | 0.52 | 0.63 | +0.12 | sell |
| Rubric Capital Management LP | 5,000,000 | 6,000,000 | +1,000,000 | 1.70 | 1.95 | +0.25 | buy |
| CITADEL ADVISORS LLC | 2,515,998 | 5,576,261 | +3,060,263 | 0.05 | 0.11 | +0.06 | buy |
| DIMENSIONAL FUND ADVISORS LP | 7,475,866 | 5,230,417 | -2,245,449 | 0.04 | 0.03 | -0.01 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 6,992,136 | 4,816,741 | -2,175,395 | 0.02 | 0.02 | -0.01 | sell |
| NORGES BANK | 0 | 4,747,472 | +4,747,472 | 0.00 | 0.02 | +0.02 | buy |
| BAKER BROS. ADVISORS LP | 4,867,723 | 4,716,831 | -150,892 | 0.77 | 0.84 | +0.06 | sell |
| JENNISON ASSOCIATES LLC | 2,982,799 | 4,481,964 | +1,499,165 | 0.06 | 0.10 | +0.04 | buy |
| Point72 Asset Management, L.P. | 890,900 | 4,473,478 | +3,582,578 | 0.04 | 0.24 | +0.20 | buy |
| BANK OF AMERICA CORP /DE/ | 3,163,821 | 4,341,381 | +1,177,560 | 0.01 | 0.01 | +0.00 | buy |
| NORTHERN TRUST CORP | 3,520,452 | 3,762,157 | +241,705 | 0.01 | 0.02 | +0.00 | buy |
| Affinity Asset Advisors, LLC | 2,800,000 | 3,750,000 | +950,000 | 4.55 | 6.49 | +1.94 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 3,715,594 | +3,715,594 | 0.00 | 0.02 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 3,457,448 | 3,715,594 | +258,146 | 0.01 | 0.02 | +0.00 | buy |
| Pictet Asset Management Holding SA | 2,673,233 | 3,468,340 | +795,107 | 0.08 | 0.12 | +0.04 | buy |
| Qube Research & Technologies Ltd | 3,450,904 | 3,454,496 | +3,592 | 0.14 | 0.14 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 3,285,906 | 3,157,008 | -128,898 | 5.47 | 5.25 | -0.22 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 699,137 | 2,988,121 | +2,288,984 | 0.02 | 0.08 | +0.07 | buy |
| D. E. Shaw & Co., Inc. | 1,392,748 | 2,972,702 | +1,579,954 | 0.03 | 0.07 | +0.03 | buy |
| MAVERICK CAPITAL LTD | 1,626,940 | 2,829,024 | +1,202,084 | 0.52 | 0.90 | +0.38 | buy |
| Bank of New York Mellon Corp | 2,735,824 | 2,790,266 | +54,442 | 0.01 | 0.02 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 6,298,000 | 2,773,874 | -3,524,126 | 0.18 | 0.09 | -0.09 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 963,282 | 2,687,870 | +1,724,588 | 0.00 | 0.02 | +0.01 | buy |
| Weiss Asset Management LP | 0 | 2,542,652 | +2,542,652 | 0.00 | 1.01 | +1.01 | buy |
| Woodline Partners LP | 1,750,017 | 2,500,673 | +750,656 | 0.18 | 0.27 | +0.09 | buy |
| HRT FINANCIAL LP | 0 | 2,463,000 | +2,463,000 | 0.00 | 0.16 | +0.16 | buy |
| CITIGROUP INC | 1,536,110 | 2,225,190 | +689,080 | 0.03 | 0.04 | +0.01 | buy |
| DME Capital Management, LP | 2,152,669 | 2,152,669 | 0 | 1.87 | 1.95 | +0.08 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 2,516,353 | 2,073,137 | -443,216 | 0.05 | 0.04 | -0.01 | sell |
| Integral Health Asset Management, LLC | 2,000,000 | 2,000,000 | 0 | 2.93 | 2.90 | -0.03 | hold |
| BlackBarn Capital Partners LP | 2,285,117 | 2,000,000 | -285,117 | 19.04 | 17.60 | -1.45 | sell |
| Candriam S.C.A. | 2,001,976 | 1,990,510 | -11,466 | 0.29 | 0.32 | +0.03 | sell |
| Nuveen, LLC | 1,955,046 | 1,970,504 | +15,458 | 0.01 | 0.02 | +0.00 | buy |
| Clearbridge Investments, LLC | 2,005,565 | 1,783,075 | -222,490 | 0.05 | 0.05 | +0.00 | sell |
| PENN DAVIS MCFARLAND INC | 1,592,623 | 1,580,191 | -12,432 | 4.32 | 4.98 | +0.67 | sell |
| Nearwater Capital Markets, Ltd | 0 | 1,500,000 | +1,500,000 | 0.00 | 0.92 | +0.92 | buy |
| MARSHALL WACE, LLP | 2,246,943 | 1,421,478 | -825,465 | 0.07 | 0.04 | -0.02 | sell |
| Polar Capital Holdings Plc | 1,578,308 | 1,376,554 | -201,754 | 0.19 | 0.14 | -0.05 | sell |
| Gotham Asset Management, LLC | 1,416,091 | 1,349,465 | -66,626 | 0.12 | 0.11 | -0.01 | sell |
| First Turn Management, LLC | 1,190,118 | 1,331,066 | +140,948 | 3.68 | 5.04 | +1.36 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 196,195 | 1,301,013 | +1,104,818 | 0.01 | 0.04 | +0.03 | buy |
| BANK OF NOVA SCOTIA | 1,310,387 | 1,238,830 | -71,557 | 0.06 | 0.07 | +0.00 | sell |
| RHUMBLINE ADVISERS | 1,113,266 | 1,178,789 | +65,523 | 0.03 | 0.03 | +0.01 | buy |
| Daiwa Securities Group Inc. | 10,019 | 1,166,320 | +1,156,301 | 0.00 | 0.09 | +0.09 | buy |
| JPMORGAN CHASE & CO | 1,537,519 | 1,137,867 | -399,652 | 0.00 | 0.00 | -0.00 | sell |
| FRED ALGER MANAGEMENT, LLC | 925,186 | 1,081,421 | +156,235 | 0.11 | 0.13 | +0.01 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 1,005,533 | 1,024,140 | +18,607 | 0.01 | 0.02 | +0.00 | buy |
| Whitefort Capital Management, LP | 1,419,000 | 1,019,000 | -400,000 | 11.96 | 8.89 | -3.07 | sell |
| Amundi | 1,480,970 | 997,226 | -483,744 | 0.01 | 0.01 | -0.00 | sell |
| Swiss National Bank | 743,446 | 942,246 | +198,800 | 0.01 | 0.02 | +0.01 | buy |
| Ensign Peak Advisors, Inc | 1,018,842 | 871,432 | -147,410 | 0.05 | 0.05 | -0.00 | sell |
| ALGERT GLOBAL LLC | 827,454 | 845,118 | +17,664 | 0.34 | 0.35 | +0.01 | buy |
| Erste Asset Management GmbH | 214,000 | 834,000 | +620,000 | 0.05 | 0.23 | +0.17 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 136,887 | 823,408 | +686,521 | 0.00 | 0.01 | +0.01 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 691,463 | 791,958 | +100,495 | 0.01 | 0.02 | +0.00 | buy |
| Legal & General Group Plc | 561,307 | 721,552 | +160,245 | 0.00 | 0.01 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 678,518 | 713,946 | +35,428 | 0.01 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 438,565 | 701,644 | +263,079 | 0.00 | 0.01 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 803,801 | 700,494 | -103,307 | 0.02 | 0.02 | +0.00 | sell |
| ING GROEP NV | 391,500 | 564,600 | +173,100 | 0.07 | 0.10 | +0.03 | buy |
| ALLIANCEBERNSTEIN L.P. | 676,344 | 550,827 | -125,517 | 0.00 | 0.01 | +0.00 | sell |
| Quantinno Capital Management LP | 76,575 | 546,694 | +470,119 | 0.00 | 0.02 | +0.02 | buy |
| Cache Advisors, LLC | 0 | 538,600 | +538,600 | 0.00 | 1.62 | +1.62 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 440,634 | 536,905 | +96,271 | 0.01 | 0.02 | +0.00 | buy |
| Brevan Howard Capital Management LP | 116,602 | 517,621 | +401,019 | 0.03 | 0.26 | +0.23 | buy |
| Russell Investments Group, Ltd. | 707,171 | 516,739 | -190,432 | 0.02 | 0.02 | -0.01 | sell |
| Jain Global LLC | 85,178 | 486,186 | +401,008 | 0.03 | 0.20 | +0.17 | buy |
| Squarepoint Ops LLC | 0 | 475,571 | +475,571 | 0.00 | 0.03 | +0.03 | buy |
| Cormorant Asset Management, LP | 750,000 | 475,000 | -275,000 | 1.05 | 0.86 | -0.19 | sell |
| FIRST TRUST ADVISORS LP | 455,865 | 468,623 | +12,758 | 0.01 | 0.01 | +0.00 | buy |
| Retirement Systems of Alabama | 552,771 | 466,350 | -86,421 | 0.05 | 0.05 | -0.00 | sell |
| BARCLAYS PLC | 1,415,848 | 426,685 | -989,163 | 0.01 | 0.00 | -0.01 | sell |
| Nicholas Investment Partners, LP | 278,425 | 419,280 | +140,855 | 0.56 | 0.84 | +0.28 | buy |
| Dorsey Wright & Associates | 577,147 | 391,662 | -185,485 | 1.98 | 2.35 | +0.37 | sell |
| TD ASSET MANAGEMENT INC | 715,282 | 386,882 | -328,400 | 0.02 | 0.01 | -0.00 | sell |
| PARNASSUS INVESTMENTS, LLC | 0 | 367,212 | +367,212 | 0.00 | 0.03 | +0.03 | buy |
| STEMPOINT CAPITAL LP | 385,800 | 348,408 | -37,392 | 2.05 | 2.13 | +0.08 | sell |
| LPL Financial LLC | 378,656 | 334,376 | -44,280 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 314,440 | 321,512 | +7,072 | 0.01 | 0.01 | +0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 325,757 | 320,187 | -5,570 | 0.02 | 0.02 | +0.00 | sell |
| Impax Asset Management Group plc | 300,000 | 300,000 | 0 | 0.06 | 0.07 | +0.01 | hold |
| STRS OHIO | 10,156 | 299,838 | +289,682 | 0.00 | 0.04 | +0.04 | buy |
| Man Group plc | 852,204 | 290,772 | -561,432 | 0.05 | 0.02 | -0.03 | sell |