| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Knoll Capital Management, LLC | 5,881,879 | 5,881,879 | 0 | 7.95 | 6.05 | -1.89 | hold |
| Point72 Asset Management, L.P. | 2,697,236 | 1,178,443 | -1,518,793 | 0.01 | 0.00 | -0.01 | sell |
| MARSHALL WACE, LLP | 0 | 627,330 | +627,330 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 604,522 | 566,956 | -37,566 | 0.01 | 0.01 | -0.00 | sell |
| Parkman Healthcare Partners LLC | 355,822 | 280,822 | -75,000 | 0.08 | 0.06 | -0.02 | sell |
| NORTHERN TRUST CORP | 200,745 | 148,668 | -52,077 | 0.00 | 0.00 | -0.00 | sell |
| BESSEMER GROUP INC | 140,843 | 140,843 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 64,300 | 88,400 | +24,100 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATURE ESTATE & INVESTMENT ADVISORS LLC | 47,328 | 47,328 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 21,136 | 21,136 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HighTower Advisors, LLC | 67,544 | 18,140 | -49,404 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 0 | 10,771 | +10,771 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cubist Systematic Strategies, LLC | 815 | 4,673 | +3,858 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 69 | +69 | 0.00 | 0.00 | 0.00 | buy |
| GROUP ONE TRADING LLC | 51 | 51 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 9,000 | 0 | -9,000 | 0.00 | 0.00 | -0.00 | sell |