| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 16,769,878 | 16,796,979 | +27,101 | 0.01 | 0.01 | -0.00 | buy |
| BlackRock, Inc. | 13,947,558 | 13,541,448 | -406,110 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 10,455,841 | 10,958,209 | +502,368 | 0.00 | 0.00 | +0.00 | buy |
| Soleus Capital Management, L.P. | 9,644,872 | 8,530,665 | -1,114,207 | 6.66 | 4.68 | -1.98 | sell |
| MORGAN STANLEY | 916,154 | 5,069,895 | +4,153,741 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 2,610,688 | 2,577,239 | -33,449 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 2,474,988 | 2,476,646 | +1,658 | 0.00 | 0.00 | -0.00 | buy |
| Quantinno Capital Management LP | 1,522,168 | 2,010,248 | +488,080 | 0.05 | 0.05 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,072,854 | 1,387,754 | +314,900 | 0.02 | 0.03 | +0.01 | buy |
| Palo Alto Investors LP | 1,256,159 | 1,298,964 | +42,805 | 3.00 | 2.34 | -0.67 | buy |
| Nuveen, LLC | 1,707,842 | 1,273,349 | -434,493 | 0.01 | 0.00 | -0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 102,563 | 1,223,755 | +1,121,192 | 0.01 | 0.06 | +0.06 | buy |
| GOLDMAN SACHS GROUP INC | 904,506 | 1,178,045 | +273,539 | 0.00 | 0.00 | +0.00 | buy |
| BAILLIE GIFFORD & CO | 1,124,031 | 1,121,274 | -2,757 | 0.01 | 0.01 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 1,218,807 | 1,041,532 | -177,275 | 0.01 | 0.01 | -0.00 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 444,747 | 1,019,969 | +575,222 | 0.00 | 0.01 | +0.01 | buy |
| C WorldWide Group Holding A/S | 971,784 | 971,784 | 0 | 0.19 | 0.22 | +0.03 | hold |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 927,400 | +927,400 | 0.00 | 0.02 | +0.02 | buy |
| Point72 Asset Management, L.P. | 116,600 | 900,496 | +783,896 | 0.00 | 0.02 | +0.01 | buy |
| ALGERT GLOBAL LLC | 682,858 | 878,998 | +196,140 | 0.15 | 0.18 | +0.03 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 910,149 | 876,816 | -33,333 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 897,120 | 858,986 | -38,134 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 486,479 | 822,385 | +335,906 | 0.01 | 0.01 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 565,763 | 752,143 | +186,380 | 0.00 | 0.00 | +0.00 | buy |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 706,075 | 707,609 | +1,534 | 0.06 | 0.06 | +0.00 | buy |
| CITADEL ADVISORS LLC | 223,557 | 675,831 | +452,274 | 0.00 | 0.01 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 564,503 | 661,297 | +96,794 | 0.02 | 0.02 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,335,490 | 646,666 | -688,824 | 0.01 | 0.01 | -0.01 | sell |
| Jump Financial, LLC | 216,442 | 561,237 | +344,795 | 0.04 | 0.09 | +0.05 | buy |
| Vestal Point Capital, LP | 400,000 | 525,000 | +125,000 | 0.23 | 0.25 | +0.01 | buy |
| BARCLAYS PLC | 398,022 | 447,255 | +49,233 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 196,823 | 414,742 | +217,919 | 0.00 | 0.00 | +0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 631,544 | 407,204 | -224,340 | 0.03 | 0.02 | -0.01 | sell |
| Legal & General Group Plc | 245,569 | 406,664 | +161,095 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 282,184 | 402,882 | +120,698 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 56,679 | 378,974 | +322,295 | 0.00 | 0.01 | +0.01 | buy |
| BNP Paribas Asset Management Holding S.A. | 1,153 | 373,392 | +372,239 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 117,367 | 352,459 | +235,092 | 0.00 | 0.01 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 332,471 | 342,953 | +10,482 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 422,280 | 319,814 | -102,466 | 0.01 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 87,231 | 314,080 | +226,849 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 342,469 | 313,218 | -29,251 | 0.01 | 0.01 | -0.00 | sell |
| Bank of New York Mellon Corp | 330,094 | 298,528 | -31,566 | 0.00 | 0.00 | -0.00 | sell |
| Engineers Gate Manager LP | 273,326 | 291,332 | +18,006 | 0.04 | 0.04 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 26,750 | 289,359 | +262,609 | 0.01 | 0.06 | +0.05 | buy |
| TUDOR INVESTMENT CORP ET AL | 606,070 | 284,645 | -321,425 | 0.05 | 0.02 | -0.03 | sell |
| SG Americas Securities, LLC | 27,724 | 278,806 | +251,082 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 250,312 | 264,894 | +14,582 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 208,908 | 259,078 | +50,170 | 0.00 | 0.01 | +0.00 | buy |
| HRT FINANCIAL LP | 363,538 | 250,862 | -112,676 | 0.02 | 0.01 | -0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 68,360 | 244,072 | +175,712 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 195,515 | 238,360 | +42,845 | 0.07 | 0.10 | +0.03 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,195,624 | 226,500 | -969,124 | 0.00 | 0.00 | -0.00 | sell |
| Swiss National Bank | 205,300 | 209,500 | +4,200 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 63,933 | 206,819 | +142,886 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 139,020 | 204,053 | +65,033 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 43,000 | 192,800 | +149,800 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 95,205 | 168,873 | +73,668 | 0.01 | 0.01 | +0.00 | buy |
| Russell Investments Group, Ltd. | 40,990 | 155,199 | +114,209 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 153,518 | +153,518 | 0.00 | 0.04 | +0.04 | buy |
| Birchview Capital, LP | 102,100 | 152,100 | +50,000 | 1.00 | 1.15 | +0.16 | buy |
| UBS Group AG | 81,975 | 148,519 | +66,544 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 31,129 | 144,728 | +113,599 | 0.00 | 0.01 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 83,198 | 140,813 | +57,615 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 137,106 | 136,030 | -1,076 | 0.00 | 0.00 | -0.00 | sell |
| Hillsdale Investment Management Inc. | 131,800 | 131,800 | 0 | 0.05 | 0.05 | -0.00 | hold |
| RHUMBLINE ADVISERS | 147,313 | 124,960 | -22,353 | 0.00 | 0.00 | -0.00 | sell |
| Eversept Partners, LP | 0 | 120,978 | +120,978 | 0.00 | 0.09 | +0.09 | buy |
| FEDERATED HERMES, INC. | 105,422 | 115,136 | +9,714 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 107,795 | 105,412 | -2,383 | 0.00 | 0.00 | -0.00 | sell |
| FOX RUN MANAGEMENT, L.L.C. | 46,818 | 99,405 | +52,587 | 0.09 | 0.20 | +0.10 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 104,196 | 99,304 | -4,892 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 110,306 | 94,094 | -16,212 | 0.00 | 0.00 | -0.00 | sell |
| Focus Partners Wealth | 0 | 88,181 | +88,181 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 26,800 | 86,900 | +60,100 | 0.00 | 0.00 | +0.00 | buy |
| Summit Trail Advisors, LLC | 88,313 | 85,264 | -3,049 | 0.02 | 0.02 | +0.00 | sell |
| Aquatic Capital Management LLC | 80,169 | 83,686 | +3,517 | 0.02 | 0.03 | +0.01 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 64,099 | 73,720 | +9,621 | 0.01 | 0.01 | +0.00 | buy |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0 | 72,949 | +72,949 | 0.00 | 0.00 | +0.00 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 44,772 | 71,286 | +26,514 | 0.01 | 0.01 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 53,281 | 68,311 | +15,030 | 0.01 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 75,774 | 67,968 | -7,806 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 22,684 | 58,795 | +36,111 | 0.02 | 0.02 | +0.00 | buy |
| STRS OHIO | 59,200 | 58,100 | -1,100 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 62,717 | 56,930 | -5,787 | 0.00 | 0.00 | -0.00 | sell |
| Hennion & Walsh Asset Management, Inc. | 41,330 | 54,245 | +12,915 | 0.02 | 0.02 | +0.00 | buy |
| Squarepoint Ops LLC | 82,167 | 53,045 | -29,122 | 0.00 | 0.00 | -0.00 | sell |
| Tidal Investments LLC | 48,564 | 51,421 | +2,857 | 0.00 | 0.00 | +0.00 | buy |
| Numerai GP LLC | 0 | 51,218 | +51,218 | 0.00 | 0.08 | +0.08 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 50,542 | +50,542 | 0.00 | 0.02 | +0.02 | buy |
| Campbell & CO Investment Adviser LLC | 29,753 | 49,367 | +19,614 | 0.03 | 0.03 | +0.00 | buy |
| Corient Private Wealth LLC | 35,027 | 46,952 | +11,925 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 55,035 | 46,781 | -8,254 | 0.00 | 0.00 | -0.00 | sell |
| JANUS HENDERSON GROUP PLC | 45,000 | 45,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| IMC-Chicago, LLC | 32,534 | 41,909 | +9,375 | 0.01 | 0.01 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 42,957 | 41,303 | -1,654 | 0.00 | 0.00 | -0.00 | sell |
| Inscription Capital, LLC | 35,372 | 40,018 | +4,646 | 0.05 | 0.05 | +0.00 | buy |
| Voleon Capital Management LP | 17,847 | 39,761 | +21,914 | 0.01 | 0.01 | +0.01 | buy |
| Amundi | 35,736 | 39,676 | +3,940 | 0.00 | 0.00 | -0.00 | buy |
| Graham Capital Management, L.P. | 10,095 | 38,857 | +28,762 | 0.00 | 0.02 | +0.01 | buy |