| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Bellevue Group AG | 1,190,697 | 1,971,935 | +781,238 | 1.65 | 2.41 | +0.77 | buy |
| Clearbridge Investments, LLC | 128,377 | 751,999 | +623,622 | 0.01 | 0.04 | +0.03 | buy |
| First Light Asset Management, LLC | 141,784 | 345,157 | +203,373 | 0.74 | 1.22 | +0.48 | buy |
| WCM INVESTMENT MANAGEMENT, LLC | 112,631 | 243,502 | +130,871 | 0.01 | 0.03 | +0.01 | buy |
| Bridgewater Associates, LP | 12,903 | 50,217 | +37,314 | 0.00 | 0.01 | +0.01 | buy |
| HighVista Strategies LLC | 124,647 | 149,739 | +25,092 | 2.00 | 1.98 | -0.02 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 1,374,292 | 1,380,219 | +5,927 | 1.32 | 1.07 | -0.25 | buy |
| SEGALL BRYANT & HAMILL, LLC | 183,935 | 187,269 | +3,334 | 0.15 | 0.13 | -0.02 | buy |
| J.Safra Asset Management Corp | 10,850 | 12,564 | +1,714 | 0.03 | 0.03 | -0.00 | buy |
| Baker Avenue Asset Management, LP | 13,143 | 13,279 | +136 | 0.02 | 0.01 | -0.00 | buy |
| E Fund Management (Hong Kong) Co., Ltd. | 243 | 328 | +85 | 0.01 | 0.01 | -0.00 | buy |
| MEEDER ASSET MANAGEMENT INC | 133 | 71 | -62 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 25,540 | 22,981 | -2,559 | 0.11 | 0.08 | -0.03 | sell |
| Avior Wealth Management, LLC | 8,647 | 5,744 | -2,903 | 0.01 | 0.01 | -0.01 | sell |
| Nantahala Capital Management, LLC | 238,746 | 222,146 | -16,600 | 0.51 | 0.43 | -0.08 | sell |
| BANQUE PICTET & CIE SA | 61,846 | 44,736 | -17,110 | 0.03 | 0.02 | -0.01 | sell |
| SummitTX Capital, L.P. | 74,842 | 57,355 | -17,487 | 0.14 | 0.09 | -0.05 | sell |
| Artisan Partners Limited Partnership | 297,432 | 270,590 | -26,842 | 0.03 | 0.02 | -0.00 | sell |
| Cormorant Asset Management, LP | 100,000 | 50,000 | -50,000 | 0.29 | 0.15 | -0.14 | sell |
| Novo Holdings A/S | 860,000 | 800,000 | -60,000 | 4.05 | 2.70 | -1.35 | sell |
| Alyeska Investment Group, L.P. | 435,581 | 362,272 | -73,309 | 0.07 | 0.05 | -0.02 | sell |
| Capital Research Global Investors | 912,688 | 836,761 | -75,927 | 0.01 | 0.01 | -0.00 | sell |
| Rosalind Advisors, Inc. | 290,000 | 200,000 | -90,000 | 6.77 | 4.32 | -2.45 | sell |
| Candriam S.C.A. | 315,022 | 208,054 | -106,968 | 0.10 | 0.05 | -0.04 | sell |
| Eversept Partners, LP | 924,193 | 629,952 | -294,241 | 2.83 | 1.90 | -0.93 | sell |