| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 7,673,868 | 8,868,907 | +1,195,039 | 0.29 | 0.36 | +0.07 | buy |
| T. Rowe Price Investment Management, Inc. | 3,552,967 | 4,022,589 | +469,622 | 0.15 | 0.19 | +0.04 | buy |
| Commodore Capital LP | 860,000 | 1,305,000 | +445,000 | 3.93 | 6.73 | +2.80 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 418,715 | +418,715 | 0.00 | 0.08 | +0.08 | buy |
| Cormorant Asset Management, LP | 685,000 | 1,100,000 | +415,000 | 2.06 | 4.83 | +2.77 | buy |
| BROWN ADVISORY INC | 0 | 367,217 | +367,217 | 0.00 | 0.04 | +0.04 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 1,586,095 | 1,929,348 | +343,253 | 0.57 | 0.72 | +0.15 | buy |
| MAVERICK CAPITAL LTD | 355,131 | 687,908 | +332,777 | 0.47 | 0.99 | +0.52 | buy |
| FRANKLIN RESOURCES INC | 2,147,656 | 2,461,775 | +314,119 | 0.05 | 0.06 | +0.01 | buy |
| Woodline Partners LP | 393,704 | 706,903 | +313,199 | 0.25 | 0.51 | +0.26 | buy |
| Allspring Global Investments Holdings, LLC | 47,388 | 343,552 | +296,164 | 0.01 | 0.04 | +0.04 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 108,012 | 295,762 | +187,750 | 0.00 | 0.01 | +0.00 | buy |
| Clearbridge Investments, LLC | 0 | 186,141 | +186,141 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 285,876 | 471,281 | +185,405 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 118,533 | 277,764 | +159,231 | 0.00 | 0.01 | +0.00 | buy |
| MACQUARIE GROUP LTD | 0 | 159,012 | +159,012 | 0.00 | 0.01 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,287,375 | 2,441,772 | +154,397 | 0.01 | 0.02 | +0.00 | buy |
| Amundi | 302,357 | 442,308 | +139,951 | 0.01 | 0.01 | +0.01 | buy |
| JENNISON ASSOCIATES LLC | 1,256,883 | 1,383,131 | +126,248 | 0.06 | 0.07 | +0.01 | buy |
| Tri Locum Partners LP | 0 | 113,344 | +113,344 | 0.00 | 2.16 | +2.16 | buy |
| Novo Holdings A/S | 845,000 | 950,000 | +105,000 | 3.98 | 3.87 | -0.11 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 189,668 | 288,006 | +98,338 | 0.01 | 0.02 | +0.01 | buy |
| WCM INVESTMENT MANAGEMENT, LLC | 0 | 92,304 | +92,304 | 0.00 | 0.02 | +0.02 | buy |
| JANE STREET GROUP, LLC | 15,682 | 106,611 | +90,929 | 0.00 | 0.01 | +0.01 | buy |
| COMERICA BANK | 188,084 | 273,025 | +84,941 | 0.06 | 0.09 | +0.03 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 657,206 | 739,153 | +81,947 | 0.70 | 0.96 | +0.25 | buy |
| First Light Asset Management, LLC | 60,284 | 139,729 | +79,445 | 0.32 | 0.92 | +0.61 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 1,867,807 | 1,934,747 | +66,940 | 1.27 | 1.41 | +0.14 | buy |
| SEI INVESTMENTS CO | 103,403 | 170,149 | +66,746 | 0.01 | 0.02 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 461,724 | 527,594 | +65,870 | 0.02 | 0.02 | +0.00 | buy |
| VANGUARD GROUP INC | 9,737,254 | 9,796,995 | +59,741 | 0.01 | 0.01 | +0.00 | buy |
| Bank of New York Mellon Corp | 412,525 | 468,579 | +56,054 | 0.01 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 1,161,777 | 1,212,443 | +50,666 | 0.01 | 0.01 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 833,618 | 876,237 | +42,619 | 0.01 | 0.01 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 698,492 | 736,739 | +38,247 | 0.01 | 0.01 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 8,193 | 40,342 | +32,149 | 0.07 | 0.23 | +0.16 | buy |
| TD ASSET MANAGEMENT INC | 281,288 | 312,426 | +31,138 | 0.02 | 0.02 | +0.00 | buy |
| Saturn V Capital Management LP | 185,175 | 215,680 | +30,505 | 5.07 | 6.15 | +1.08 | buy |
| STATE STREET CORP | 3,337,092 | 3,367,147 | +30,055 | 0.01 | 0.01 | +0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 62 | 29,272 | +29,210 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 280,875 | 307,516 | +26,641 | 0.02 | 0.02 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 54,841 | 81,338 | +26,497 | 0.01 | 0.01 | +0.00 | buy |
| SECTORAL ASSET MANAGEMENT INC | 8,500 | 33,730 | +25,230 | 0.23 | 1.04 | +0.81 | buy |
| Squarepoint Ops LLC | 0 | 23,356 | +23,356 | 0.00 | 0.01 | +0.01 | buy |
| HighVista Strategies LLC | 9,321 | 32,313 | +22,992 | 0.23 | 0.89 | +0.66 | buy |
| Tower Research Capital LLC (TRC) | 1,040 | 23,535 | +22,495 | 0.00 | 0.03 | +0.03 | buy |
| ALGERT GLOBAL LLC | 13,310 | 34,752 | +21,442 | 0.04 | 0.09 | +0.05 | buy |
| CITIGROUP INC | 144,867 | 165,795 | +20,928 | 0.01 | 0.01 | +0.00 | buy |
| Lisanti Capital Growth, LLC | 0 | 19,340 | +19,340 | 0.00 | 0.35 | +0.35 | buy |
| FIRST TRUST ADVISORS LP | 63,826 | 78,926 | +15,100 | 0.00 | 0.01 | +0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 13,946 | +13,946 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 119,082 | 131,749 | +12,667 | 0.01 | 0.01 | +0.00 | buy |
| NEW YORK LIFE INVESTMENT MANAGEMENT LLC | 0 | 12,661 | +12,661 | 0.00 | 0.01 | +0.01 | buy |
| EFG Asset Management (North America) Corp. | 19,425 | 30,442 | +11,017 | 0.23 | 0.40 | +0.17 | buy |
| RHUMBLINE ADVISERS | 148,294 | 159,295 | +11,001 | 0.01 | 0.01 | +0.00 | buy |
| Creative Planning | 16,638 | 27,280 | +10,642 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 10,463 | +10,463 | 0.00 | 0.04 | +0.04 | buy |
| B. Metzler seel. Sohn & Co. AG | 0 | 10,409 | +10,409 | 0.00 | 0.01 | +0.01 | buy |
| ADAR1 Capital Management, LLC | 2,000 | 12,250 | +10,250 | 0.04 | 0.19 | +0.15 | buy |
| Campbell & CO Investment Adviser LLC | 13,473 | 23,248 | +9,775 | 0.08 | 0.15 | +0.07 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 17,258 | 26,738 | +9,480 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 53,997 | 62,967 | +8,970 | 0.02 | 0.03 | +0.00 | buy |
| Kynam Capital Management, LP | 745,000 | 753,240 | +8,240 | 5.66 | 5.95 | +0.29 | buy |
| ROYAL BANK OF CANADA | 3,289 | 11,031 | +7,742 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 19,600 | 27,300 | +7,700 | 0.01 | 0.01 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 43,055 | 49,292 | +6,237 | 0.00 | 0.00 | +0.00 | buy |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 44,699 | 50,813 | +6,114 | 0.03 | 0.04 | +0.01 | buy |
| Neuberger Berman Group LLC | 102,311 | 108,092 | +5,781 | 0.01 | 0.01 | +0.00 | buy |
| ACUTA CAPITAL PARTNERS, LLC | 104,830 | 110,400 | +5,570 | 4.65 | 7.03 | +2.38 | buy |
| Everhart Financial Group, Inc. | 0 | 5,464 | +5,464 | 0.00 | 0.11 | +0.11 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 42,693 | 47,961 | +5,268 | 0.00 | 0.00 | +0.00 | buy |
| Pathstone Holdings, LLC | 23,273 | 28,373 | +5,100 | 0.01 | 0.01 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 18,064 | 22,956 | +4,892 | 0.00 | 0.00 | +0.00 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 0 | 4,529 | +4,529 | 0.00 | 0.00 | +0.00 | buy |
| SEGALL BRYANT & HAMILL, LLC | 158,021 | 162,432 | +4,411 | 0.20 | 0.22 | +0.02 | buy |
| Cresset Asset Management, LLC | 0 | 4,404 | +4,404 | 0.00 | 0.00 | +0.00 | buy |
| Corton Capital Inc. | 0 | 3,838 | +3,838 | 0.00 | 0.15 | +0.15 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 0 | 3,667 | +3,667 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 54,136 | 57,476 | +3,340 | 0.00 | 0.01 | +0.00 | buy |
| Swiss National Bank | 178,000 | 181,300 | +3,300 | 0.01 | 0.01 | +0.00 | buy |
| CIBC Asset Management Inc | 0 | 3,026 | +3,026 | 0.00 | 0.00 | +0.00 | buy |
| Knollwood Investment Advisory, LLC | 0 | 3,000 | +3,000 | 0.00 | 0.03 | +0.03 | buy |
| Assenagon Asset Management S.A. | 0 | 2,826 | +2,826 | 0.00 | 0.00 | +0.00 | buy |
| J. Goldman & Co LP | 0 | 2,700 | +2,700 | 0.00 | 0.01 | +0.01 | buy |
| Envestnet Portfolio Solutions, Inc. | 0 | 2,675 | +2,675 | 0.00 | 0.00 | +0.00 | buy |
| Baird Financial Group, Inc. | 16,473 | 19,133 | +2,660 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | 2,500 | +2,500 | 0.00 | 0.05 | +0.05 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 3,770 | 6,252 | +2,482 | 0.01 | 0.01 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 2,473 | +2,473 | 0.00 | 0.01 | +0.01 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,346 | 20,485 | +2,139 | 0.00 | 0.01 | +0.00 | buy |
| Nicholas Investment Partners, LP | 85,644 | 87,230 | +1,586 | 0.60 | 0.68 | +0.08 | buy |
| Legal & General Group Plc | 94,783 | 96,310 | +1,527 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 7,495 | 9,000 | +1,505 | 0.00 | 0.00 | +0.00 | buy |
| Cercano Management LLC | 272,151 | 273,608 | +1,457 | 0.52 | 0.55 | +0.03 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 15,840 | 17,269 | +1,429 | 0.02 | 0.03 | +0.01 | buy |
| Calamos Advisors LLC | 10,165 | 11,533 | +1,368 | 0.00 | 0.00 | +0.00 | buy |
| Avior Wealth Management, LLC | 4,702 | 5,831 | +1,129 | 0.01 | 0.02 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 7,148 | 8,222 | +1,074 | 0.00 | 0.00 | +0.00 | buy |
| Arizona State Retirement System | 24,783 | 25,796 | +1,013 | 0.01 | 0.01 | +0.00 | buy |
| Bellevue Group AG | 13,244 | 14,210 | +966 | 0.01 | 0.02 | +0.00 | buy |