| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 380,828 | 2,154,110 | +1,773,282 | 0.29 | 2.21 | +1.92 | buy |
| Pictet Asset Management Holding SA | 0 | 1,163,961 | +1,163,961 | 0.00 | 0.06 | +0.06 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 210,352 | 572,297 | +361,945 | 0.00 | 0.00 | +0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 20,367 | 362,717 | +342,350 | 0.00 | 0.07 | +0.06 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 274,524 | 598,905 | +324,381 | 0.08 | 0.33 | +0.25 | buy |
| LORD, ABBETT & CO. LLC | 0 | 283,518 | +283,518 | 0.00 | 0.05 | +0.05 | buy |
| Artisan Partners Limited Partnership | 0 | 271,421 | +271,421 | 0.00 | 0.02 | +0.02 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 267,000 | +267,000 | 0.00 | 0.02 | +0.02 | buy |
| VANGUARD GROUP INC | 3,014,568 | 3,226,938 | +212,370 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 20,050 | 182,297 | +162,247 | 0.00 | 0.01 | +0.01 | buy |
| D. E. Shaw & Co., Inc. | 0 | 128,492 | +128,492 | 0.00 | 0.01 | +0.01 | buy |
| NATIONAL BANK OF CANADA /FI/ | 131,000 | 239,000 | +108,000 | 0.01 | 0.02 | +0.01 | buy |
| Invesco Ltd. | 28,374 | 135,731 | +107,357 | 0.00 | 0.00 | +0.00 | buy |
| NATIXIS | 0 | 80,500 | +80,500 | 0.00 | 0.03 | +0.03 | buy |
| Woodline Partners LP | 0 | 74,850 | +74,850 | 0.00 | 0.04 | +0.04 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,045,057 | 1,119,129 | +74,072 | 0.00 | 0.01 | +0.00 | buy |
| UBS Group AG | 26,651 | 85,955 | +59,304 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 144,002 | 184,359 | +40,357 | 0.01 | 0.01 | +0.01 | buy |
| TD ASSET MANAGEMENT INC | 0 | 37,800 | +37,800 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 40,146 | 66,708 | +26,562 | 0.06 | 0.18 | +0.12 | buy |
| Virtu Financial LLC | 0 | 26,501 | +26,501 | 0.00 | 0.10 | +0.10 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 20,163 | 39,238 | +19,075 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 15,350 | +15,350 | 0.00 | 0.00 | +0.00 | buy |
| HighVista Strategies LLC | 0 | 14,362 | +14,362 | 0.00 | 0.24 | +0.24 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 384,748 | 397,685 | +12,937 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 12,793 | +12,793 | 0.00 | 0.02 | +0.02 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 20,641 | 32,874 | +12,233 | 0.00 | 0.00 | +0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 0 | 11,795 | +11,795 | 0.00 | 0.00 | +0.00 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 10,742 | +10,742 | 0.00 | 0.04 | +0.04 | buy |
| Parkwood LLC | 0 | 10,198 | +10,198 | 0.00 | 0.07 | +0.07 | buy |
| BARCLAYS PLC | 241,261 | 251,415 | +10,154 | 0.00 | 0.01 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 944 | 9,708 | +8,764 | 0.00 | 0.01 | +0.00 | buy |
| Quantbot Technologies LP | 0 | 8,000 | +8,000 | 0.00 | 0.02 | +0.02 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 55,243 | 63,085 | +7,842 | 0.00 | 0.01 | +0.00 | buy |
| LPL Financial LLC | 0 | 6,857 | +6,857 | 0.00 | 0.00 | +0.00 | buy |
| E Fund Management Co., Ltd. | 0 | 6,533 | +6,533 | 0.00 | 0.02 | +0.02 | buy |
| Altium Capital Management LLC | 0 | 6,485 | +6,485 | 0.00 | 0.21 | +0.21 | buy |
| SEI INVESTMENTS CO | 0 | 6,174 | +6,174 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 0 | 5,953 | +5,953 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 0 | 5,876 | +5,876 | 0.00 | 0.00 | +0.00 | buy |
| JGP Global Gestao de Recursos Ltda. | 0 | 5,688 | +5,688 | 0.00 | 0.16 | +0.16 | buy |
| Jasper Ridge Partners, L.P. | 0 | 5,639 | +5,639 | 0.00 | 0.01 | +0.01 | buy |
| Atom Investors LP | 19,386 | 24,931 | +5,545 | 0.10 | 0.20 | +0.10 | buy |
| China Universal Asset Management Co., Ltd. | 1,458 | 6,837 | +5,379 | 0.01 | 0.06 | +0.05 | buy |
| JPMORGAN CHASE & CO | 72,411 | 77,599 | +5,188 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 5,089 | +5,089 | 0.00 | 0.02 | +0.02 | buy |
| Old Well Partners, LLC | 0 | 4,600 | +4,600 | 0.00 | 0.20 | +0.20 | buy |
| XTX Topco Ltd | 0 | 4,386 | +4,386 | 0.00 | 0.04 | +0.04 | buy |
| Gotham Asset Management, LLC | 14,319 | 18,473 | +4,154 | 0.01 | 0.02 | +0.01 | buy |
| ROYAL BANK OF CANADA | 12,043 | 16,132 | +4,089 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 50,552 | 54,534 | +3,982 | 0.01 | 0.02 | +0.01 | buy |
| Legal & General Group Plc | 43,154 | 46,828 | +3,674 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 8,821 | 12,321 | +3,500 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 0 | 3,000 | +3,000 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 177,376 | 180,222 | +2,846 | 0.00 | 0.00 | +0.00 | buy |
| BIT Capital GmbH | 0 | 2,489 | +2,489 | 0.00 | 0.01 | +0.01 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 137,443 | 139,802 | +2,359 | 0.00 | 0.00 | +0.00 | buy |
| WHITTIER TRUST CO | 0 | 2,000 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 10,395 | 12,281 | +1,886 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 1,857 | +1,857 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 30,456 | 32,232 | +1,776 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 1,500 | +1,500 | 0.00 | 0.03 | +0.03 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 1,250 | +1,250 | 0.00 | 0.00 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 3,547 | 4,796 | +1,249 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 16,406 | 17,406 | +1,000 | 0.03 | 0.07 | +0.04 | buy |
| NISA INVESTMENT ADVISORS, LLC | 656 | 1,256 | +600 | 0.00 | 0.00 | +0.00 | buy |
| KBC Group NV | 811 | 1,263 | +452 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 8,775 | 9,181 | +406 | 0.00 | 0.00 | +0.00 | buy |
| ELEVATION WEALTH PARTNERS, LLC | 0 | 400 | +400 | 0.00 | 0.01 | +0.01 | buy |
| Ameritas Investment Partners, Inc. | 5,067 | 5,318 | +251 | 0.00 | 0.01 | +0.00 | buy |
| SIGNATUREFD, LLC | 204 | 213 | +9 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |
| Global Retirement Partners, LLC | 28 | 35 | +7 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 54,390 | 54,390 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TEXAS TREASURY SAFEKEEPING TRUST CO | 4,230 | 4,230 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Ensign Peak Advisors, Inc | 18,550 | 18,550 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Daiwa Securities Group Inc. | 227 | 227 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEA Management Company, LLC | 2,909,956 | 2,909,956 | 0 | 5.15 | 8.92 | +3.76 | hold |
| MetLife Investment Management, LLC | 27,123 | 27,123 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Allianz Asset Management GmbH | 11,900 | 11,900 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CWM, LLC | 207 | 207 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Focused Wealth Management, Inc | 300 | 300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NewEdge Advisors, LLC | 5 | 5 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Truvestments Capital LLC | 216 | 216 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Nan Fung Group Holdings Ltd | 40,070 | 40,070 | 0 | 0.74 | 1.15 | +0.40 | hold |
| Bell Investment Advisors, Inc | 19 | 19 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Frazier Life Sciences Management, L.P. | 2,371,304 | 2,371,304 | 0 | 3.61 | 5.83 | +2.21 | hold |
| DIMENSIONAL FUND ADVISORS LP | 96,948 | 96,948 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FIDUCIARY TRUST CO | 20,000 | 20,000 | 0 | 0.01 | 0.02 | +0.01 | hold |
| METROPOLITAN LIFE INSURANCE CO/NY | 2,968 | 2,968 | 0 | 0.00 | 0.01 | +0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 14,670 | 14,670 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Covestor Ltd | 7 | 4 | -3 | 0.00 | 0.00 | 0.00 | sell |
| Allworth Financial LP | 5 | 0 | -5 | 0.00 | 0.00 | -0.00 | sell |
| PRIVATE TRUST CO NA | 82 | 56 | -26 | 0.00 | 0.00 | +0.00 | sell |
| US BANCORP \DE\ | 110 | 62 | -48 | 0.00 | 0.00 | +0.00 | sell |
| Newbridge Financial Services Group, Inc. | 65 | 0 | -65 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 25,640 | 25,537 | -103 | 0.00 | 0.00 | +0.00 | sell |
| HEADINVEST, LLC | 110 | 0 | -110 | 0.00 | 0.00 | -0.00 | sell |