| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 8,799,053 | 8,801,567 | +2,514 | 15.00 | 12.57 | -2.43 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 4,975,181 | 5,007,931 | +32,750 | 1.16 | 0.84 | -0.32 | buy |
| Capital International Investors | 4,158,726 | 4,210,221 | +51,495 | 0.29 | 0.25 | -0.04 | buy |
| FMR LLC | 3,693,610 | 2,478,527 | -1,215,083 | 0.06 | 0.03 | -0.03 | sell |
| Capital World Investors | 1,622,687 | 2,249,582 | +626,895 | 0.07 | 0.08 | +0.01 | buy |
| CITADEL ADVISORS LLC | 1,032,298 | 1,425,517 | +393,219 | 0.22 | 0.23 | +0.02 | buy |
| Temasek Holdings (Private) Ltd | 862,643 | 845,729 | -16,914 | 0.86 | 0.66 | -0.20 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 539,769 | 758,752 | +218,983 | 0.02 | 0.02 | +0.00 | buy |
| BlackRock, Inc. | 657,501 | 694,618 | +37,117 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 204,846 | 543,323 | +338,477 | 0.05 | 0.10 | +0.06 | buy |
| MORGAN STANLEY | 464,472 | 497,437 | +32,965 | 0.01 | 0.01 | -0.00 | buy |
| Siren, L.L.C. | 465,000 | 465,000 | 0 | 3.83 | 2.69 | -1.14 | hold |
| BANK OF AMERICA CORP /DE/ | 405,273 | 439,336 | +34,063 | 0.01 | 0.01 | -0.00 | buy |
| Baird Financial Group, Inc. | 349,651 | 368,978 | +19,327 | 0.16 | 0.14 | -0.02 | buy |
| Man Group plc | 241,922 | 307,463 | +65,541 | 0.15 | 0.16 | +0.01 | buy |
| Capital International, Inc./CA/ | 302,243 | 305,477 | +3,234 | 0.69 | 0.61 | -0.08 | buy |
| Candriam S.C.A. | 259,731 | 289,735 | +30,004 | 0.40 | 0.37 | -0.03 | buy |
| TWO SIGMA INVESTMENTS, LP | 33,543 | 286,552 | +253,009 | 0.01 | 0.06 | +0.05 | buy |
| UBS Group AG | 415,330 | 258,589 | -156,741 | 0.02 | 0.01 | -0.01 | sell |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 110,586 | 249,758 | +139,172 | 0.02 | 0.03 | +0.01 | buy |
| FIRST TRUST ADVISORS LP | 241,426 | 245,823 | +4,397 | 0.05 | 0.04 | -0.01 | buy |
| M&G Plc | 138,163 | 223,445 | +85,282 | 0.21 | 0.32 | +0.10 | buy |
| Nuveen, LLC | 196,429 | 197,431 | +1,002 | 0.02 | 0.01 | -0.00 | buy |
| JPMORGAN CHASE & CO | 77,538 | 188,405 | +110,867 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 184,356 | 185,544 | +1,188 | 0.04 | 0.03 | -0.01 | buy |
| MARSHALL WACE, LLP | 172,643 | 177,987 | +5,344 | 0.05 | 0.04 | -0.01 | buy |
| Capital International Sarl | 173,879 | 175,542 | +1,663 | 0.85 | 0.71 | -0.14 | buy |
| GOLDMAN SACHS GROUP INC | 96,677 | 157,701 | +61,024 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 201,641 | 132,031 | -69,610 | 0.01 | 0.01 | -0.01 | sell |
| Lansforsakringar Fondforvaltning AB (publ) | 0 | 123,352 | +123,352 | 0.00 | 0.01 | +0.01 | buy |
| Artisan Partners Limited Partnership | 137,216 | 115,374 | -21,842 | 0.07 | 0.05 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 65,456 | 101,980 | +36,524 | 0.03 | 0.04 | +0.01 | buy |
| JENNISON ASSOCIATES LLC | 154,465 | 100,698 | -53,767 | 0.03 | 0.02 | -0.01 | sell |
| LAZARD ASSET MANAGEMENT LLC | 62,917 | 90,348 | +27,431 | 0.03 | 0.04 | +0.01 | buy |
| Patient Square Capital LP | 80,542 | 90,020 | +9,478 | 4.24 | 3.97 | -0.27 | buy |
| Qube Research & Technologies Ltd | 0 | 81,279 | +81,279 | 0.00 | 0.03 | +0.03 | buy |
| Squarepoint Ops LLC | 74,124 | 78,561 | +4,437 | 0.05 | 0.04 | -0.00 | buy |
| CAPITAL INTERNATIONAL LTD /CA/ | 76,515 | 77,161 | +646 | 0.84 | 0.72 | -0.12 | buy |
| ROYAL BANK OF CANADA | 70,391 | 71,861 | +1,470 | 0.00 | 0.00 | -0.00 | buy |
| ABN AMRO INVESTMENT SOLUTIONS | 47,564 | 65,524 | +17,960 | 0.18 | 0.16 | -0.02 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 59,611 | 60,525 | +914 | 0.00 | 0.00 | -0.00 | buy |
| Legal & General Group Plc | 59,812 | 59,890 | +78 | 0.00 | 0.00 | -0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 57,320 | 59,831 | +2,511 | 0.06 | 0.05 | -0.01 | buy |
| VAN ECK ASSOCIATES CORP | 108,305 | 55,002 | -53,303 | 0.02 | 0.01 | -0.01 | sell |
| Woodline Partners LP | 0 | 54,064 | +54,064 | 0.00 | 0.05 | +0.05 | buy |
| WELLS FARGO & COMPANY/MN | 52,063 | 53,086 | +1,023 | 0.00 | 0.00 | -0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 56,879 | 46,733 | -10,146 | 0.00 | 0.00 | -0.00 | sell |
| BARINGS LLC | 42,815 | 42,815 | 0 | 0.21 | 0.22 | +0.01 | hold |
| NORTHERN TRUST CORP | 36,132 | 39,647 | +3,515 | 0.00 | 0.00 | -0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 33,728 | 37,070 | +3,342 | 0.01 | 0.01 | -0.00 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 32,532 | 35,781 | +3,249 | 0.11 | 0.11 | -0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 155,002 | 35,504 | -119,498 | 0.34 | 0.06 | -0.28 | sell |
| Atle Fund Management AB | 41,717 | 35,180 | -6,537 | 3.92 | 2.70 | -1.22 | sell |
| Fiera Capital Corp | 33,782 | 34,516 | +734 | 0.03 | 0.04 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 23,740 | 33,808 | +10,068 | 0.02 | 0.02 | -0.00 | buy |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 43,430 | 33,660 | -9,770 | 0.19 | 0.13 | -0.06 | sell |
| ASSETMARK, INC | 29,569 | 32,399 | +2,830 | 0.02 | 0.02 | -0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 49,344 | 29,641 | -19,703 | 0.01 | 0.01 | -0.01 | sell |
| AIA Group Ltd | 26,077 | 29,282 | +3,205 | 0.11 | 0.10 | -0.01 | buy |
| Quadrature Capital Ltd | 0 | 29,203 | +29,203 | 0.00 | 0.07 | +0.07 | buy |
| Slow Capital, Inc. | 28,492 | 28,237 | -255 | 1.10 | 0.94 | -0.16 | sell |
| DEUTSCHE BANK AG\ | 27,877 | 27,886 | +9 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 25,222 | 27,716 | +2,494 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 27,105 | 27,617 | +512 | 0.00 | 0.00 | -0.00 | buy |
| Capital Group Private Client Services, Inc. | 28,656 | 23,206 | -5,450 | 0.14 | 0.09 | -0.05 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 20,828 | 22,738 | +1,910 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 23,438 | 22,050 | -1,388 | 0.01 | 0.01 | -0.00 | sell |
| Asset Management One Co., Ltd. | 21,346 | 21,346 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Trexquant Investment LP | 4,037 | 20,683 | +16,646 | 0.01 | 0.04 | +0.03 | buy |
| RAYMOND JAMES FINANCIAL INC | 19,047 | 20,273 | +1,226 | 0.00 | 0.00 | -0.00 | buy |
| Erste Asset Management GmbH | 21,900 | 20,100 | -1,800 | 0.06 | 0.05 | -0.01 | sell |
| Quantinno Capital Management LP | 8,312 | 19,814 | +11,502 | 0.00 | 0.01 | +0.00 | buy |
| Capital Group Investment Management Pte. Ltd. | 16,688 | 16,840 | +152 | 0.85 | 0.72 | -0.12 | buy |
| Engineers Gate Manager LP | 0 | 16,302 | +16,302 | 0.00 | 0.06 | +0.06 | buy |
| Nan Fung Group Holdings Ltd | 15,722 | 15,722 | 0 | 3.85 | 3.41 | -0.44 | hold |
| XTX Topco Ltd | 5,153 | 15,064 | +9,911 | 0.03 | 0.06 | +0.03 | buy |
| Tidal Investments LLC | 12,633 | 13,561 | +928 | 0.01 | 0.01 | -0.00 | buy |
| Creative Planning | 10,158 | 12,703 | +2,545 | 0.00 | 0.00 | +0.00 | buy |
| GUGGENHEIM CAPITAL LLC | 12,245 | 12,352 | +107 | 0.03 | 0.02 | -0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 12,346 | 12,346 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 12,273 | +12,273 | 0.00 | 2.21 | +2.21 | buy |
| ADAR1 Capital Management, LLC | 11,701 | 11,701 | 0 | 0.21 | 0.16 | -0.05 | hold |
| STIFEL FINANCIAL CORP | 11,469 | 11,028 | -441 | 0.00 | 0.00 | -0.00 | sell |
| Pinpoint Asset Management (Singapore) Pte. Ltd. | 9,610 | 11,009 | +1,399 | 0.67 | 0.64 | -0.03 | buy |
| Crossmark Global Holdings, Inc. | 7,661 | 10,755 | +3,094 | 0.03 | 0.04 | +0.01 | buy |
| Bellevue Group AG | 3,812 | 10,474 | +6,662 | 0.03 | 0.06 | +0.04 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 10,486 | 9,798 | -688 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 75,953 | 9,442 | -66,511 | 0.02 | 0.00 | -0.02 | sell |
| State of Wyoming | 0 | 8,698 | +8,698 | 0.00 | 0.25 | +0.25 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 7,815 | 8,175 | +360 | 0.01 | 0.01 | -0.00 | buy |
| Generali Investments, Management Co LLC | 0 | 8,000 | +8,000 | 0.00 | 0.04 | +0.04 | buy |
| MACKENZIE FINANCIAL CORP | 6,081 | 7,786 | +1,705 | 0.00 | 0.00 | +0.00 | buy |
| Mitsubishi UFJ Trust & Banking Corp | 710 | 7,573 | +6,863 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 7,498 | +7,498 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 14,808 | 7,461 | -7,347 | 0.01 | 0.00 | -0.00 | sell |
| JONES FINANCIAL COMPANIES LLLP | 6,465 | 6,865 | +400 | 0.00 | 0.00 | -0.00 | buy |
| B. Metzler seel. Sohn & Co. AG | 3,866 | 6,706 | +2,840 | 0.01 | 0.02 | +0.01 | buy |
| Neuberger Berman Group LLC | 4,404 | 6,502 | +2,098 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 6,200 | 6,400 | +200 | 0.02 | 0.02 | -0.01 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 5,863 | 6,365 | +502 | 0.00 | 0.00 | -0.00 | buy |