| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MORGAN STANLEY | 173,032 | 738,140 | +565,108 | 0.00 | 0.01 | +0.01 | buy |
| Paradigm Biocapital Advisors LP | 200,336 | 616,024 | +415,688 | 1.57 | 3.96 | +2.38 | buy |
| CITADEL ADVISORS LLC | 47,034 | 317,113 | +270,079 | 0.01 | 0.05 | +0.04 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2,700,088 | 2,937,170 | +237,082 | 0.07 | 0.06 | -0.01 | buy |
| FMR LLC | 1,660,011 | 1,848,063 | +188,052 | 0.02 | 0.02 | -0.00 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 4,974,289 | 5,098,904 | +124,615 | 0.82 | 0.73 | -0.09 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 5,280 | 103,063 | +97,783 | 0.00 | 0.01 | +0.01 | buy |
| Siren, L.L.C. | 563,314 | 653,721 | +90,407 | 6.33 | 5.34 | -0.99 | buy |
| MILLENNIUM MANAGEMENT LLC | 57,125 | 145,763 | +88,638 | 0.01 | 0.02 | +0.01 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 87,200 | +87,200 | 0.00 | 0.03 | +0.03 | buy |
| Artisan Partners Limited Partnership | 199,838 | 279,648 | +79,810 | 0.07 | 0.08 | +0.01 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 225,854 | 284,394 | +58,540 | 0.25 | 0.24 | -0.01 | buy |
| UBS Group AG | 35,724 | 91,468 | +55,744 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 32,299 | 86,329 | +54,030 | 0.01 | 0.02 | +0.01 | buy |
| VAN ECK ASSOCIATES CORP | 38,888 | 89,042 | +50,154 | 0.01 | 0.02 | +0.01 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 50,000 | +50,000 | 0.00 | 0.01 | +0.01 | buy |
| JPMORGAN CHASE & CO | 9,780 | 55,359 | +45,579 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 44,293 | +44,293 | 0.00 | 0.02 | +0.02 | buy |
| M&G Plc | 173,075 | 193,163 | +20,088 | 0.14 | 0.22 | +0.08 | buy |
| GOLDMAN SACHS GROUP INC | 30,658 | 47,404 | +16,746 | 0.00 | 0.00 | +0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 11,874 | 27,923 | +16,049 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 15,193 | +15,193 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 4,434 | 19,244 | +14,810 | 0.00 | 0.02 | +0.01 | buy |
| FIL Ltd | 0 | 13,640 | +13,640 | 0.00 | 0.00 | +0.00 | buy |
| Atle Fund Management AB | 0 | 10,900 | +10,900 | 0.00 | 0.95 | +0.95 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 6,600 | 16,199 | +9,599 | 0.04 | 0.07 | +0.04 | buy |
| Jump Financial, LLC | 0 | 9,426 | +9,426 | 0.00 | 0.04 | +0.04 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 3,042 | 11,678 | +8,636 | 0.00 | 0.00 | +0.00 | buy |
| Baird Financial Group, Inc. | 287,114 | 295,562 | +8,448 | 0.13 | 0.10 | -0.02 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 26,752 | 34,960 | +8,208 | 0.18 | 0.19 | +0.01 | buy |
| NORTHERN TRUST CORP | 12,374 | 18,870 | +6,496 | 0.00 | 0.00 | +0.00 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 6,365 | +6,365 | 0.00 | 1.03 | +1.03 | buy |
| OMERS ADMINISTRATION Corp | 0 | 5,700 | +5,700 | 0.00 | 0.01 | +0.01 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 56,582 | 62,142 | +5,560 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,391 | 6,883 | +5,492 | 0.01 | 0.03 | +0.02 | buy |
| GUGGENHEIM CAPITAL LLC | 0 | 4,569 | +4,569 | 0.00 | 0.01 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 744 | 5,295 | +4,551 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 16,848 | 21,166 | +4,318 | 0.03 | 0.03 | -0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,569 | 12,173 | +3,604 | 0.00 | 0.00 | +0.00 | buy |
| BARINGS LLC | 67,998 | 71,422 | +3,424 | 0.36 | 0.31 | -0.04 | buy |
| AIA Group Ltd | 21,665 | 24,587 | +2,922 | 0.13 | 0.11 | -0.02 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 0 | 2,715 | +2,715 | 0.00 | 0.09 | +0.09 | buy |
| Hudson Bay Capital Management LP | 5,000 | 7,500 | +2,500 | 0.01 | 0.01 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 57,384 | 59,831 | +2,447 | 0.01 | 0.01 | -0.00 | buy |
| Fiera Capital Corp | 6,011 | 8,442 | +2,431 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 11,917 | 14,056 | +2,139 | 0.01 | 0.01 | -0.00 | buy |
| Jefferies Financial Group Inc. | 0 | 2,000 | +2,000 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 978 | 2,974 | +1,996 | 0.04 | 0.11 | +0.08 | buy |
| Bayesian Capital Management, LP | 0 | 1,791 | +1,791 | 0.00 | 0.04 | +0.04 | buy |
| Bridgewater Associates, LP | 0 | 1,610 | +1,610 | 0.00 | 0.00 | +0.00 | buy |
| CAPITAL INTERNATIONAL LTD /CA/ | 74,548 | 76,048 | +1,500 | 0.72 | 0.57 | -0.15 | buy |
| Tempus Wealth Planning, LLC | 0 | 1,420 | +1,420 | 0.00 | 0.08 | +0.08 | buy |
| ASSETMARK, INC | 17,158 | 18,541 | +1,383 | 0.01 | 0.01 | -0.00 | buy |
| Vise Technologies, Inc. | 0 | 1,346 | +1,346 | 0.00 | 0.02 | +0.02 | buy |
| Empowered Funds, LLC | 0 | 1,192 | +1,192 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 467 | 1,561 | +1,094 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 1,000 | 2,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Capital International Sarl | 151,742 | 152,710 | +968 | 0.88 | 0.65 | -0.22 | buy |
| Creative Planning | 0 | 903 | +903 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 8,510 | 9,403 | +893 | 0.21 | 0.16 | -0.05 | buy |
| ROYAL BANK OF CANADA | 68,744 | 69,490 | +746 | 0.00 | 0.00 | -0.00 | buy |
| US BANCORP \DE\ | 100 | 741 | +641 | 0.00 | 0.00 | +0.00 | buy |
| MML INVESTORS SERVICES, LLC | 4,434 | 4,985 | +551 | 0.00 | 0.00 | -0.00 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 30,427 | 30,945 | +518 | 0.08 | 0.07 | -0.01 | buy |
| &PARTNERS | 1,033 | 1,532 | +499 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 37,764 | 38,252 | +488 | 0.00 | 0.00 | -0.00 | buy |
| Crossmark Global Holdings, Inc. | 4,829 | 5,288 | +459 | 0.02 | 0.02 | -0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 21,015 | 21,456 | +441 | 0.00 | 0.00 | -0.00 | buy |
| Capital Group Investment Management Pte. Ltd. | 16,030 | 16,436 | +406 | 0.72 | 0.58 | -0.15 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 300 | 691 | +391 | 0.01 | 0.03 | +0.02 | buy |
| Envestnet Portfolio Solutions, Inc. | 1,016 | 1,304 | +288 | 0.00 | 0.00 | +0.00 | buy |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 995 | 1,211 | +216 | 0.00 | 0.00 | -0.00 | buy |
| Parallel Advisors, LLC | 0 | 209 | +209 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 4,416 | 4,586 | +170 | 0.04 | 0.03 | -0.01 | buy |
| Kestra Advisory Services, LLC | 1,434 | 1,603 | +169 | 0.00 | 0.00 | -0.00 | buy |
| LVW Advisors, LLC | 1,001 | 1,132 | +131 | 0.03 | 0.03 | -0.00 | buy |
| SIGNATUREFD, LLC | 9 | 128 | +119 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 1,899 | 2,009 | +110 | 0.00 | 0.00 | -0.00 | buy |
| Cetera Investment Advisers | 1,788 | 1,891 | +103 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 15 | 84 | +69 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 142 | 209 | +67 | 0.00 | 0.00 | +0.00 | buy |
| Hexagon Capital Partners LLC | 0 | 59 | +59 | 0.00 | 0.00 | +0.00 | buy |
| BROWN BROTHERS HARRIMAN & CO | 3 | 45 | +42 | 0.00 | 0.00 | +0.00 | buy |
| Brooklyn Investment Group | 0 | 38 | +38 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 1,314 | 1,347 | +33 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 86 | 115 | +29 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 20 | 47 | +27 | 0.00 | 0.00 | +0.00 | buy |
| Operose Advisors LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL SECURITIES, INC. | 90 | 99 | +9 | 0.00 | 0.00 | -0.00 | buy |
| Steward Partners Investment Advisory, LLC | 699 | 707 | +8 | 0.00 | 0.00 | -0.00 | buy |
| Rakuten Securities, Inc. | 0 | 8 | +8 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 1,819 | 1,827 | +8 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 12,297 | 12,302 | +5 | 0.00 | 0.00 | -0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 5 | 10 | +5 | 0.00 | 0.00 | +0.00 | buy |
| Vestmark Advisory Solutions, Inc. | 1,648 | 1,652 | +4 | 0.01 | 0.01 | -0.00 | buy |
| HUNTINGTON NATIONAL BANK | 1 | 5 | +4 | 0.00 | 0.00 | +0.00 | buy |
| Geneos Wealth Management Inc. | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Private Wealth Group LLC | 4 | 6 | +2 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 399 | 401 | +2 | 0.00 | 0.00 | -0.00 | buy |
| Allworth Financial LP | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |