| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 212,750 | 291,532 | +78,782 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 371,177 | 411,696 | +40,519 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 30,690 | +30,690 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 997,621 | 1,024,608 | +26,987 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 803,469 | 828,321 | +24,852 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 10,085 | +10,085 | 0.00 | 0.00 | +0.00 | buy |
| CANTOR FITZGERALD, L. P. | 20,000 | 30,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 23,610 | 28,810 | +5,200 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 377,086 | 381,354 | +4,268 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 3,309 | 3,879 | +570 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 7,409 | 7,907 | +498 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 1,439 | 1,915 | +476 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 19,837 | 20,167 | +330 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,211 | 1,327 | +116 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 284 | 318 | +34 | 0.00 | 0.00 | 0.00 | buy |
| SBI Securities Co., Ltd. | 561 | 565 | +4 | 0.00 | 0.00 | -0.00 | buy |
| BVF INC/IL | 19,822,436 | 19,822,436 | 0 | 1.51 | 1.44 | -0.07 | hold |
| State of Tennessee, Department of Treasury | 5,126 | 5,126 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Quinn Opportunity Partners LLC | 10,100 | 10,100 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Eversept Partners, LP | 100,752 | 100,752 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Activest Wealth Management | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Strengthening Families & Communities, LLC | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Silverberg Bernstein Capital Management LLC | 10,000 | 10,000 | 0 | 0.02 | 0.01 | -0.00 | hold |
| GF FUND MANAGEMENT CO. LTD. | 2,454 | 2,454 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SEI INVESTMENTS CO | 24,897 | 24,897 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| DEUTSCHE BANK AG\ | 253,375 | 253,375 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SJS Investment Consulting Inc. | 200 | 0 | -200 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 64,090 | 63,601 | -489 | 0.00 | 0.00 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 813 | 0 | -813 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 6,864 | 3,075 | -3,789 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 151,461 | 145,999 | -5,462 | 0.00 | 0.00 | -0.00 | sell |
| Banque Cantonale Vaudoise | 26,712 | 18,440 | -8,272 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 22,406 | 12,642 | -9,764 | 0.00 | 0.00 | -0.00 | sell |
| Handelsbanken Fonder AB | 130,000 | 105,000 | -25,000 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 237,558 | 198,686 | -38,872 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 212,184 | 135,841 | -76,343 | 0.00 | 0.00 | -0.00 | sell |
| PLATINUM INVESTMENT MANAGEMENT LTD | 739,342 | 0 | -739,342 | 0.08 | 0.00 | -0.08 | sell |
| BlackRock, Inc. | 1,156,591 | 411,307 | -745,284 | 0.00 | 0.00 | -0.00 | sell |