| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BVF INC/IL | 19,822,436 | 19,822,436 | 0 | 1.74 | 1.21 | -0.53 | hold |
| WELLS FARGO & COMPANY/MN | 1,004,284 | 1,004,041 | -243 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 624,367 | 840,127 | +215,760 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 792,657 | 773,594 | -19,063 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 524,278 | 519,274 | -5,004 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 390,165 | 340,082 | -50,083 | 0.00 | 0.00 | -0.00 | sell |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 405,658 | 232,953 | -172,705 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 267,233 | 207,606 | -59,627 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 39,091 | 102,825 | +63,734 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 92,351 | +92,351 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 63,601 | 61,854 | -1,747 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 11,125 | 24,064 | +12,939 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 17,852 | 16,197 | -1,655 | 0.00 | 0.00 | -0.00 | sell |
| Quadrature Capital Ltd | 0 | 12,991 | +12,991 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 10,398 | +10,398 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 10,327 | +10,327 | 0.00 | 0.00 | +0.00 | buy |
| Quinn Opportunity Partners LLC | 10,100 | 10,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Silverberg Bernstein Capital Management LLC | 10,000 | 10,000 | 0 | 0.02 | 0.01 | -0.01 | hold |
| BARCLAYS PLC | 5,791 | 7,278 | +1,487 | 0.00 | 0.00 | -0.00 | buy |
| Banque Cantonale Vaudoise | 7,021 | 7,021 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Mirae Asset Global Investments Co., Ltd. | 5,247 | 4,552 | -695 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 7,009 | 4,101 | -2,908 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 2,811 | 4,012 | +1,201 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 2,410 | 2,699 | +289 | 0.00 | 0.00 | -0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 2,242 | 2,084 | -158 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 0 | 1,197 | +1,197 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Activest Wealth Management | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Strengthening Families & Communities, LLC | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Caitong International Asset Management Co., Ltd | 3 | 35 | +32 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 131,458 | 0 | -131,458 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 11,530 | 0 | -11,530 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 17,276 | 0 | -17,276 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 6,620 | 0 | -6,620 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 14,304 | 0 | -14,304 | 0.00 | 0.00 | -0.00 | sell |
| Dauntless Investment Group, LLC | 107,489 | 0 | -107,489 | 0.83 | 0.00 | -0.83 | sell |
| NORTHERN TRUST CORP | 278,513 | 0 | -278,513 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 96,907 | 0 | -96,907 | 0.00 | 0.00 | -0.00 | sell |