| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BVF INC/IL | 18,834,936 | 19,522,436 | +687,500 | 2.11 | 2.16 | +0.05 | buy |
| China Universal Asset Management Co., Ltd. | 11,621 | 19,021 | +7,400 | 0.01 | 0.01 | +0.00 | buy |
| ALPS ADVISORS INC | 77,376 | 76,630 | -746 | 0.00 | 0.00 | -0.00 | sell |
| Banque Cantonale Vaudoise | 25,418 | 18,562 | -6,856 | 0.00 | 0.00 | -0.00 | sell |
| Redmile Group, LLC | 1,807,704 | 1,694,167 | -113,537 | 0.44 | 0.38 | -0.06 | sell |