| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 7,322,501 | 6,797,584 | -524,917 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 3,689,201 | 3,638,567 | -50,634 | 0.03 | 0.03 | -0.00 | sell |
| PFIZER INC | 3,457,815 | 3,457,815 | 0 | 17.34 | 14.63 | -2.72 | hold |
| TCG Crossover Management, LLC | 2,666,216 | 2,387,461 | -278,755 | 1.05 | 0.72 | -0.32 | sell |
| ARMISTICE CAPITAL, LLC | 1,800,000 | 1,978,000 | +178,000 | 0.52 | 0.69 | +0.17 | buy |
| TWO SIGMA INVESTMENTS, LP | 992,463 | 1,832,114 | +839,651 | 0.02 | 0.02 | -0.00 | buy |
| STATE STREET CORP | 1,843,409 | 1,828,472 | -14,937 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 1,623,489 | 1,557,107 | -66,382 | 0.00 | 0.00 | -0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 252,294 | 1,441,521 | +1,189,227 | 0.01 | 0.06 | +0.05 | buy |
| Qube Research & Technologies Ltd | 1,324,740 | 1,201,635 | -123,105 | 0.02 | 0.02 | -0.00 | sell |
| CITADEL ADVISORS LLC | 413,646 | 1,180,988 | +767,342 | 0.00 | 0.01 | +0.01 | buy |
| FEDERATED HERMES, INC. | 1,094,999 | 1,140,715 | +45,716 | 0.02 | 0.02 | -0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 1,187,029 | 949,874 | -237,155 | 0.02 | 0.01 | -0.01 | sell |
| Vestal Point Capital, LP | 0 | 905,465 | +905,465 | 0.00 | 0.27 | +0.27 | buy |
| GOLDMAN SACHS GROUP INC | 1,116,150 | 756,875 | -359,275 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 810,072 | 674,718 | -135,354 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 1,259,441 | 576,352 | -683,089 | 0.01 | 0.00 | -0.01 | sell |
| KENNEDY CAPITAL MANAGEMENT LLC | 442,778 | 552,641 | +109,863 | 0.11 | 0.12 | +0.01 | buy |
| Nextech Invest, Ltd. | 539,394 | 539,394 | 0 | 0.62 | 0.40 | -0.22 | hold |
| TANG CAPITAL MANAGEMENT LLC | 569,698 | 538,658 | -31,040 | 0.33 | 0.29 | -0.04 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 547,476 | 525,174 | -22,302 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 547,472 | 520,955 | -26,517 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 472,420 | 485,764 | +13,344 | 0.00 | 0.00 | -0.00 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 495,477 | 474,503 | -20,974 | 0.01 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 81,565 | 427,093 | +345,528 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 142,782 | 406,340 | +263,558 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 358,257 | 358,257 | 0 | 0.55 | 0.54 | -0.01 | hold |
| Invesco Ltd. | 302,100 | 316,654 | +14,554 | 0.00 | 0.00 | -0.00 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 0 | 312,620 | +312,620 | 0.00 | 2.37 | +2.37 | buy |
| Susquehanna Portfolio Strategies, LLC | 301,245 | 301,245 | 0 | 0.06 | 0.05 | -0.01 | hold |
| Nantahala Capital Management, LLC | 300,000 | 300,000 | 0 | 0.21 | 0.20 | -0.01 | hold |
| AQR CAPITAL MANAGEMENT LLC | 318,985 | 285,118 | -33,867 | 0.00 | 0.00 | -0.00 | sell |
| WASATCH ADVISORS LP | 269,149 | 281,857 | +12,708 | 0.02 | 0.02 | +0.00 | buy |
| HRT FINANCIAL LP | 260,970 | 270,302 | +9,332 | 0.01 | 0.01 | -0.00 | buy |
| CAXTON ASSOCIATES LLP | 454,517 | 260,016 | -194,501 | 0.11 | 0.06 | -0.04 | sell |
| NOMURA HOLDINGS INC | 0 | 253,609 | +253,609 | 0.00 | 0.02 | +0.02 | buy |
| ExodusPoint Capital Management, LP | 188,908 | 251,012 | +62,104 | 0.02 | 0.03 | +0.00 | buy |
| Bank of New York Mellon Corp | 268,583 | 236,714 | -31,869 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 2,315,361 | 229,807 | -2,085,554 | 0.04 | 0.00 | -0.04 | sell |
| Rangeley Capital, LLC | 395,800 | 223,990 | -171,810 | 4.04 | 2.56 | -1.48 | sell |
| FRANKLIN RESOURCES INC | 203,947 | 216,788 | +12,841 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 309,113 | 199,908 | -109,205 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 37,871 | 185,495 | +147,624 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 195,036 | 179,496 | -15,540 | 0.04 | 0.03 | -0.01 | sell |
| Y-Intercept (Hong Kong) Ltd | 124,835 | 172,808 | +47,973 | 0.03 | 0.03 | +0.00 | buy |
| J. Goldman & Co LP | 0 | 156,799 | +156,799 | 0.00 | 0.08 | +0.08 | buy |
| DEUTSCHE BANK AG\ | 145,284 | 147,522 | +2,238 | 0.00 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 394,737 | 146,387 | -248,350 | 0.04 | 0.01 | -0.03 | sell |
| JPMORGAN CHASE & CO | 31,995 | 143,313 | +111,318 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 34,636 | 137,185 | +102,549 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 188,271 | 133,818 | -54,453 | 0.03 | 0.02 | -0.01 | sell |
| GSA CAPITAL PARTNERS LLP | 42,098 | 133,252 | +91,154 | 0.04 | 0.09 | +0.04 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 101,838 | 131,974 | +30,136 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 154,309 | 116,800 | -37,509 | 0.00 | 0.00 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 124,321 | 110,974 | -13,347 | 0.00 | 0.00 | -0.00 | sell |
| LPL Financial LLC | 111,239 | 110,694 | -545 | 0.00 | 0.00 | -0.00 | sell |
| Swiss National Bank | 123,100 | 108,000 | -15,100 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 10,000 | 97,611 | +87,611 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 99,886 | 90,969 | -8,917 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 73,779 | 89,147 | +15,368 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 18,804 | 88,232 | +69,428 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 78,164 | 86,231 | +8,067 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 53,499 | 85,492 | +31,993 | 0.00 | 0.00 | +0.00 | buy |
| Tidal Investments LLC | 0 | 83,581 | +83,581 | 0.00 | 0.00 | +0.00 | buy |
| TEMA ETFS LLC | 48,801 | 83,581 | +34,780 | 0.04 | 0.06 | +0.01 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 82,482 | 82,482 | 0 | 0.03 | 0.02 | -0.00 | hold |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 29,963 | 81,322 | +51,359 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 87,196 | 80,492 | -6,704 | 0.00 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 30,143 | 78,587 | +48,444 | 0.00 | 0.00 | +0.00 | buy |
| Voleon Capital Management LP | 184,977 | 75,537 | -109,440 | 0.05 | 0.02 | -0.03 | sell |
| MARSHALL WACE, LLP | 332,535 | 75,163 | -257,372 | 0.00 | 0.00 | -0.00 | sell |
| Quantinno Capital Management LP | 66,245 | 74,540 | +8,295 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 9,634 | 73,853 | +64,219 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 73,720 | 73,720 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Headlands Technologies LLC | 86,211 | 73,043 | -13,168 | 0.09 | 0.09 | +0.00 | sell |
| PLATINUM INVESTMENT MANAGEMENT LTD | 72,527 | 72,527 | 0 | 0.20 | 0.19 | -0.01 | hold |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 70,650 | 70,750 | +100 | 0.00 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 56,826 | 69,453 | +12,627 | 0.00 | 0.00 | +0.00 | buy |
| MANGROVE PARTNERS IM, LLC | 0 | 69,260 | +69,260 | 0.00 | 0.06 | +0.06 | buy |
| UBS Group AG | 166,917 | 68,246 | -98,671 | 0.00 | 0.00 | -0.00 | sell |
| ZACKS INVESTMENT MANAGEMENT | 148,704 | 66,978 | -81,726 | 0.01 | 0.01 | -0.01 | sell |
| GLOBEFLEX CAPITAL L P | 11,128 | 59,331 | +48,203 | 0.02 | 0.10 | +0.07 | buy |
| Creative Planning | 56,927 | 58,120 | +1,193 | 0.00 | 0.00 | -0.00 | buy |
| ADAR1 Capital Management, LLC | 58,091 | 57,591 | -500 | 0.05 | 0.04 | -0.01 | sell |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 57,500 | 57,500 | 0 | 0.33 | 0.23 | -0.10 | hold |
| BARCLAYS PLC | 168,407 | 56,357 | -112,050 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 101,516 | 53,663 | -47,853 | 0.00 | 0.00 | -0.00 | sell |
| Allspring Global Investments Holdings, LLC | 46,574 | 51,923 | +5,349 | 0.00 | 0.00 | +0.00 | buy |
| Longaeva Partners L.P. | 0 | 50,205 | +50,205 | 0.00 | 0.03 | +0.03 | buy |
| Yelin Lapidot Holdings Management Ltd. | 46,665 | 46,665 | 0 | 0.11 | 0.10 | -0.01 | hold |
| Legal & General Group Plc | 60,526 | 43,350 | -17,176 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 60,523 | 43,341 | -17,182 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 28,599 | 42,657 | +14,058 | 0.01 | 0.01 | -0.00 | buy |
| Quinn Opportunity Partners LLC | 41,263 | 41,263 | 0 | 0.02 | 0.02 | +0.00 | hold |
| STRS OHIO | 23,300 | 40,400 | +17,100 | 0.00 | 0.00 | +0.00 | buy |
| Weiss Asset Management LP | 0 | 36,305 | +36,305 | 0.00 | 0.01 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 24,965 | 36,229 | +11,264 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 24,882 | 35,232 | +10,350 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 36,976 | 34,298 | -2,678 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 33,810 | 33,035 | -775 | 0.00 | 0.00 | -0.00 | sell |