| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 6,802,938 | 7,322,501 | +519,563 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 8,561,232 | 7,229,603 | -1,331,629 | 0.00 | 0.00 | +0.00 | sell |
| D. E. Shaw & Co., Inc. | 3,347,163 | 3,689,201 | +342,038 | 0.02 | 0.03 | +0.01 | buy |
| PFIZER INC | 3,457,815 | 3,457,815 | 0 | 6.73 | 17.34 | +10.61 | hold |
| TCG Crossover Management, LLC | 1,617,365 | 2,666,216 | +1,048,851 | 0.68 | 1.05 | +0.37 | buy |
| Point72 Asset Management, L.P. | 0 | 2,315,361 | +2,315,361 | 0.00 | 0.04 | +0.04 | buy |
| STATE STREET CORP | 1,873,086 | 1,843,409 | -29,677 | 0.00 | 0.00 | +0.00 | sell |
| ARMISTICE CAPITAL, LLC | 1,200,000 | 1,800,000 | +600,000 | 0.32 | 0.52 | +0.20 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,670,179 | 1,623,489 | -46,690 | 0.00 | 0.00 | +0.00 | sell |
| Qube Research & Technologies Ltd | 1,486,864 | 1,324,740 | -162,124 | 0.02 | 0.02 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 2,131,555 | 1,259,441 | -872,114 | 0.01 | 0.01 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 1,464,413 | 1,187,029 | -277,384 | 0.02 | 0.02 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 736,563 | 1,116,150 | +379,587 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 680,885 | 1,094,999 | +414,114 | 0.01 | 0.02 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 992,463 | +992,463 | 0.00 | 0.02 | +0.02 | buy |
| MORGAN STANLEY | 1,662,221 | 810,072 | -852,149 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 12,900 | 619,900 | +607,000 | 0.00 | 0.01 | +0.01 | buy |
| TANG CAPITAL MANAGEMENT LLC | 1,393,800 | 569,698 | -824,102 | 0.46 | 0.33 | -0.12 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 609,773 | 547,476 | -62,297 | 0.00 | 0.00 | +0.00 | sell |
| NORTHERN TRUST CORP | 599,219 | 547,472 | -51,747 | 0.00 | 0.00 | +0.00 | sell |
| Nextech Invest, Ltd. | 1,408,394 | 539,394 | -869,000 | 1.83 | 0.62 | -1.21 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 557,742 | 495,477 | -62,265 | 0.00 | 0.01 | +0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 665,752 | 472,420 | -193,332 | 0.00 | 0.00 | -0.00 | sell |
| CAXTON ASSOCIATES LLP | 604,785 | 454,517 | -150,268 | 0.14 | 0.11 | -0.03 | sell |
| Arbiter Partners Capital Management LLC | 452,789 | 452,789 | 0 | 2.64 | 2.89 | +0.25 | hold |
| KENNEDY CAPITAL MANAGEMENT LLC | 442,703 | 442,778 | +75 | 0.08 | 0.11 | +0.03 | buy |
| CITADEL ADVISORS LLC | 151,465 | 413,646 | +262,181 | 0.00 | 0.00 | +0.00 | buy |
| Rangeley Capital, LLC | 695,400 | 395,800 | -299,600 | 5.56 | 4.04 | -1.52 | sell |
| Trexquant Investment LP | 0 | 394,737 | +394,737 | 0.00 | 0.04 | +0.04 | buy |
| Ikarian Capital, LLC | 226,257 | 358,257 | +132,000 | 0.39 | 0.55 | +0.16 | buy |
| MARSHALL WACE, LLP | 237,903 | 332,535 | +94,632 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 223,822 | 318,985 | +95,163 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 463,348 | 309,113 | -154,235 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 238,056 | 302,100 | +64,044 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 273,695 | 301,245 | +27,550 | 0.04 | 0.06 | +0.02 | buy |
| Nantahala Capital Management, LLC | 0 | 300,000 | +300,000 | 0.00 | 0.21 | +0.21 | buy |
| WASATCH ADVISORS LP | 506,867 | 269,149 | -237,718 | 0.02 | 0.02 | -0.00 | sell |
| Bank of New York Mellon Corp | 205,687 | 268,583 | +62,896 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 1,207,267 | 261,756 | -945,511 | 0.02 | 0.01 | -0.01 | sell |
| HRT FINANCIAL LP | 396,868 | 260,970 | -135,898 | 0.01 | 0.01 | -0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 222,480 | 252,294 | +29,814 | 0.01 | 0.01 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 257,775 | 203,947 | -53,828 | 0.00 | 0.00 | +0.00 | sell |
| ALGERT GLOBAL LLC | 243,326 | 195,036 | -48,290 | 0.03 | 0.04 | +0.00 | sell |
| ExodusPoint Capital Management, LP | 241,498 | 188,908 | -52,590 | 0.03 | 0.02 | -0.00 | sell |
| Jump Financial, LLC | 0 | 188,271 | +188,271 | 0.00 | 0.03 | +0.03 | buy |
| Voleon Capital Management LP | 152,056 | 184,977 | +32,921 | 0.03 | 0.05 | +0.02 | buy |
| BARCLAYS PLC | 169,969 | 168,407 | -1,562 | 0.00 | 0.00 | +0.00 | sell |
| UBS Group AG | 400,136 | 166,917 | -233,219 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 254,401 | 154,309 | -100,092 | 0.00 | 0.00 | -0.00 | sell |
| ZACKS INVESTMENT MANAGEMENT | 158,080 | 148,704 | -9,376 | 0.01 | 0.01 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 192,544 | 145,284 | -47,260 | 0.00 | 0.00 | +0.00 | sell |
| Nuveen, LLC | 142,782 | 142,782 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Y-Intercept (Hong Kong) Ltd | 283,539 | 124,835 | -158,704 | 0.06 | 0.03 | -0.02 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 125,112 | 124,321 | -791 | 0.00 | 0.00 | +0.00 | sell |
| Swiss National Bank | 113,200 | 123,100 | +9,900 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 119,744 | 111,239 | -8,505 | 0.00 | 0.00 | +0.00 | sell |
| HUSSMAN STRATEGIC ADVISORS, INC. | 0 | 105,000 | +105,000 | 0.00 | 0.30 | +0.30 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 32,103 | 101,838 | +69,735 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 83,666 | 101,516 | +17,850 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 51,341 | 99,886 | +48,545 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 79,951 | 91,999 | +12,048 | 0.00 | 0.01 | +0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0 | 91,019 | +91,019 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 99,374 | 87,196 | -12,178 | 0.00 | 0.00 | +0.00 | sell |
| Headlands Technologies LLC | 12,877 | 86,211 | +73,334 | 0.01 | 0.09 | +0.08 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 64,914 | 82,482 | +17,568 | 0.01 | 0.03 | +0.01 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 59,174 | 82,127 | +22,953 | 0.08 | 0.15 | +0.07 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 87,316 | 81,565 | -5,751 | 0.00 | 0.00 | +0.00 | sell |
| SG Americas Securities, LLC | 38,256 | 78,164 | +39,908 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 62,107 | 73,779 | +11,672 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 73,720 | 73,720 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PLATINUM INVESTMENT MANAGEMENT LTD | 86,930 | 72,527 | -14,403 | 0.05 | 0.20 | +0.15 | sell |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 15,000 | 70,650 | +55,650 | 0.00 | 0.00 | +0.00 | buy |
| Monaco Asset Management SAM | 710,936 | 70,253 | -640,683 | 2.26 | 0.25 | -2.01 | sell |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 68,057 | +68,057 | 0.00 | 0.01 | +0.01 | buy |
| Quantinno Capital Management LP | 51,776 | 66,245 | +14,469 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 51,806 | 60,526 | +8,720 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 61,182 | 60,523 | -659 | 0.00 | 0.00 | +0.00 | sell |
| ADAR1 Capital Management, LLC | 82,591 | 58,091 | -24,500 | 0.07 | 0.05 | -0.02 | sell |
| Engineers Gate Manager LP | 0 | 58,071 | +58,071 | 0.00 | 0.01 | +0.01 | buy |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 57,500 | 57,500 | 0 | 0.29 | 0.33 | +0.04 | hold |
| Creative Planning | 44,835 | 56,927 | +12,092 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 187,570 | 56,826 | -130,744 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 30,927 | 53,499 | +22,572 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 0 | 49,531 | +49,531 | 0.00 | 0.00 | +0.00 | buy |
| TEMA ETFS LLC | 0 | 48,801 | +48,801 | 0.00 | 0.04 | +0.04 | buy |
| Brevan Howard Capital Management LP | 135,233 | 47,850 | -87,383 | 0.02 | 0.01 | -0.01 | sell |
| Yelin Lapidot Holdings Management Ltd. | 46,665 | 46,665 | 0 | 0.08 | 0.11 | +0.03 | hold |
| Allspring Global Investments Holdings, LLC | 42,500 | 46,574 | +4,074 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 22,471 | 42,306 | +19,835 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 14,755 | 42,098 | +27,343 | 0.01 | 0.04 | +0.03 | buy |
| DekaBank Deutsche Girozentrale | 42,000 | 42,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AlphaQuest LLC | 26,450 | 41,456 | +15,006 | 0.01 | 0.03 | +0.01 | buy |
| Quinn Opportunity Partners LLC | 61,263 | 41,263 | -20,000 | 0.04 | 0.02 | -0.02 | sell |
| AMERIPRISE FINANCIAL INC | 37,761 | 37,871 | +110 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 34,172 | 36,976 | +2,804 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 31,245 | 34,636 | +3,391 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 32,429 | 33,810 | +1,381 | 0.00 | 0.00 | +0.00 | buy |
| Numerai GP LLC | 67,919 | 32,348 | -35,571 | 0.08 | 0.05 | -0.04 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 32,653 | 32,173 | -480 | 0.00 | 0.00 | +0.00 | sell |
| JPMORGAN CHASE & CO | 214,779 | 31,995 | -182,784 | 0.00 | 0.00 | -0.00 | sell |