| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 4,455,770 | 8,928,086 | +4,472,316 | 0.01 | 0.03 | +0.01 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 1,162,000 | 4,075,098 | +2,913,098 | 0.33 | 1.10 | +0.77 | buy |
| VANGUARD GROUP INC | 6,287,655 | 9,089,391 | +2,801,736 | 0.01 | 0.01 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 4,459,691 | 6,950,567 | +2,490,876 | 0.04 | 0.07 | +0.03 | buy |
| BlackRock, Inc. | 6,549,942 | 7,515,193 | +965,251 | 0.01 | 0.01 | +0.00 | buy |
| SG Americas Securities, LLC | 12,963 | 542,446 | +529,483 | 0.00 | 0.12 | +0.12 | buy |
| UBS Group AG | 182,886 | 707,730 | +524,844 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Asset Management, L.P. | 2,300,643 | 2,788,939 | +488,296 | 0.41 | 0.39 | -0.02 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 4,944,757 | 5,414,505 | +469,748 | 0.03 | 0.03 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 2,429,450 | 2,795,441 | +365,991 | 0.06 | 0.07 | +0.01 | buy |
| Siren, L.L.C. | 1,309,652 | 1,609,652 | +300,000 | 3.35 | 3.64 | +0.29 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 5,885,248 | 6,141,014 | +255,766 | 2.58 | 2.59 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,848,133 | 2,098,841 | +250,708 | 0.01 | 0.01 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 1,390,110 | 1,591,666 | +201,556 | 0.02 | 0.02 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 168,493 | 355,174 | +186,681 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 2,838,484 | 2,990,838 | +152,354 | 0.01 | 0.01 | +0.00 | buy |
| SEGALL BRYANT & HAMILL, LLC | 0 | 150,398 | +150,398 | 0.00 | 0.11 | +0.11 | buy |
| NORTHERN TRUST CORP | 730,516 | 879,814 | +149,298 | 0.01 | 0.01 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 172,786 | 277,370 | +104,584 | 0.01 | 0.02 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 655,418 | 759,126 | +103,708 | 0.01 | 0.01 | +0.00 | buy |
| STEMPOINT CAPITAL LP | 213,815 | 317,060 | +103,245 | 3.28 | 4.07 | +0.79 | buy |
| First Turn Management, LLC | 353,376 | 453,376 | +100,000 | 2.86 | 4.15 | +1.29 | buy |
| MPM BioImpact LLC | 525,845 | 617,035 | +91,190 | 4.03 | 4.48 | +0.45 | buy |
| AMERICAN CENTURY COMPANIES INC | 386,886 | 477,298 | +90,412 | 0.01 | 0.01 | +0.00 | buy |
| Ikarian Capital, LLC | 426,913 | 516,431 | +89,518 | 6.77 | 7.54 | +0.77 | buy |
| Soleus Capital Management, L.P. | 0 | 85,000 | +85,000 | 0.00 | 0.33 | +0.33 | buy |
| BNP Paribas Asset Management Holding S.A. | 491,381 | 576,068 | +84,687 | 0.06 | 0.07 | +0.01 | buy |
| Fisher Asset Management, LLC | 482,099 | 559,287 | +77,188 | 0.01 | 0.01 | +0.00 | buy |
| Affinity Asset Advisors, LLC | 400,000 | 460,000 | +60,000 | 3.17 | 3.67 | +0.50 | buy |
| CITIGROUP INC | 64,825 | 120,759 | +55,934 | 0.00 | 0.01 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 271,747 | 325,276 | +53,529 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 0 | 50,000 | +50,000 | 0.00 | 0.02 | +0.02 | buy |
| Invesco Ltd. | 255,300 | 298,254 | +42,954 | 0.00 | 0.00 | +0.00 | buy |
| Nicholas Investment Partners, LP | 93,860 | 127,283 | +33,423 | 0.44 | 0.57 | +0.13 | buy |
| Bank of New York Mellon Corp | 311,940 | 344,765 | +32,825 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 0 | 29,361 | +29,361 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 130,900 | 159,400 | +28,500 | 0.00 | 0.01 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 109,425 | 137,752 | +28,327 | 0.17 | 0.21 | +0.04 | buy |
| Aquatic Capital Management LLC | 0 | 27,712 | +27,712 | 0.00 | 0.04 | +0.04 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 40,000 | 65,000 | +25,000 | 0.00 | 0.01 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 22,348 | 43,105 | +20,757 | 0.01 | 0.02 | +0.01 | buy |
| Pathstone Holdings, LLC | 0 | 20,428 | +20,428 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 210,122 | 229,004 | +18,882 | 0.01 | 0.01 | +0.00 | buy |
| Legal & General Group Plc | 70,496 | 88,939 | +18,443 | 0.00 | 0.00 | +0.00 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 0 | 18,117 | +18,117 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 0 | 17,217 | +17,217 | 0.00 | 0.00 | +0.00 | buy |
| Hood River Capital Management LLC | 834,912 | 851,400 | +16,488 | 0.69 | 0.64 | -0.05 | buy |
| WELLS FARGO & COMPANY/MN | 84,891 | 100,916 | +16,025 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 108,719 | 124,078 | +15,359 | 0.01 | 0.01 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 134,087 | 148,956 | +14,869 | 0.01 | 0.01 | +0.00 | buy |
| Proficio Capital Partners LLC | 0 | 14,674 | +14,674 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 60,743 | 74,985 | +14,242 | 0.02 | 0.02 | +0.00 | buy |
| GILDER GAGNON HOWE & CO LLC | 12,615 | 25,044 | +12,429 | 0.01 | 0.01 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 64,192 | 76,264 | +12,072 | 0.00 | 0.00 | +0.00 | buy |
| Decheng Capital LLC | 157,958 | 167,958 | +10,000 | 1.91 | 1.84 | -0.07 | buy |
| Brevan Howard Capital Management LP | 0 | 9,777 | +9,777 | 0.00 | 0.01 | +0.01 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 65,394 | 75,103 | +9,709 | 0.01 | 0.01 | +0.00 | buy |
| ProShare Advisors LLC | 19,434 | 29,089 | +9,655 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 92,530 | 101,720 | +9,190 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 54,326 | 63,077 | +8,751 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 8,206 | +8,206 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 44,935 | 53,020 | +8,085 | 0.01 | 0.01 | +0.00 | buy |
| Aberdeen Group plc | 35,467 | 43,389 | +7,922 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 147,691 | 155,426 | +7,735 | 0.01 | 0.01 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 16,811 | 24,003 | +7,192 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 19,808 | 26,836 | +7,028 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 452 | 7,412 | +6,960 | 0.00 | 0.01 | +0.01 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 46,444 | 53,163 | +6,719 | 0.01 | 0.01 | +0.00 | buy |
| MOODY ALDRICH PARTNERS LLC | 139,130 | 144,366 | +5,236 | 1.29 | 1.37 | +0.07 | buy |
| HSBC HOLDINGS PLC | 7,764 | 12,552 | +4,788 | 0.00 | 0.00 | +0.00 | buy |
| Rock Springs Capital Management LP | 289,400 | 294,100 | +4,700 | 0.48 | 0.57 | +0.09 | buy |
| CASTLEARK MANAGEMENT LLC | 73,340 | 77,780 | +4,440 | 0.15 | 0.14 | -0.01 | buy |
| China Universal Asset Management Co., Ltd. | 15,393 | 19,664 | +4,271 | 0.09 | 0.09 | +0.01 | buy |
| Arizona State Retirement System | 19,301 | 23,469 | +4,168 | 0.01 | 0.01 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 3,969 | +3,969 | 0.00 | 0.02 | +0.02 | buy |
| Pier Capital, LLC | 108,361 | 111,999 | +3,638 | 0.78 | 0.82 | +0.04 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 77,709 | 81,156 | +3,447 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 24,693 | 27,687 | +2,994 | 0.03 | 0.04 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,125 | 15,095 | +2,970 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 19,000 | 21,800 | +2,800 | 0.00 | 0.00 | +0.00 | buy |
| SANDERS MORRIS HARRIS LLC | 18,600 | 21,100 | +2,500 | 0.16 | 0.16 | +0.00 | buy |
| Allianz Asset Management GmbH | 14,200 | 16,400 | +2,200 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 4,700 | 6,900 | +2,200 | 0.00 | 0.00 | +0.00 | buy |
| Advisors Asset Management, Inc. | 2,806 | 4,913 | +2,107 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 41,607 | 43,599 | +1,992 | 0.01 | 0.01 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 17,339 | 19,219 | +1,880 | 0.00 | 0.00 | +0.00 | buy |
| KBC Group NV | 2,193 | 3,712 | +1,519 | 0.00 | 0.00 | +0.00 | buy |
| NATIXIS ADVISORS, LLC | 44,346 | 45,683 | +1,337 | 0.00 | 0.00 | -0.00 | buy |
| Harvest Fund Management Co., Ltd | 0 | 1,299 | +1,299 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 7,883 | 9,174 | +1,291 | 0.01 | 0.02 | +0.00 | buy |
| KEYBANK NATIONAL ASSOCIATION/OH | 8,176 | 9,352 | +1,176 | 0.00 | 0.00 | +0.00 | buy |
| XPONANCE, INC. | 5,116 | 6,284 | +1,168 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 4,909 | 6,071 | +1,162 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 0 | 1,022 | +1,022 | 0.00 | 0.01 | +0.01 | buy |
| ASSETMARK, INC | 17,147 | 18,161 | +1,014 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 985 | +985 | 0.00 | 0.01 | +0.01 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 4,216 | 5,038 | +822 | 0.00 | 0.00 | +0.00 | buy |
| Venturi Wealth Management, LLC | 0 | 800 | +800 | 0.00 | 0.00 | +0.00 | buy |
| State of New Jersey Common Pension Fund D | 37,341 | 38,049 | +708 | 0.01 | 0.01 | -0.00 | buy |
| Janney Montgomery Scott LLC | 4,375 | 4,975 | +600 | 0.00 | 0.00 | +0.00 | buy |