| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 11,379,207 | 16,518,419 | +5,139,212 | 0.01 | 0.01 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 2,536,233 | 4,465,872 | +1,929,639 | 0.02 | 0.02 | +0.01 | buy |
| BlackRock, Inc. | 7,140,692 | 9,054,431 | +1,913,739 | 0.00 | 0.00 | +0.00 | buy |
| Commodore Capital LP | 4,075,478 | 5,650,000 | +1,574,522 | 2.70 | 4.54 | +1.84 | buy |
| FRANKLIN RESOURCES INC | 0 | 1,200,096 | +1,200,096 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 429,516 | 1,336,010 | +906,494 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 2,420,767 | 3,109,503 | +688,736 | 0.24 | 0.26 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 2,010,633 | 2,613,221 | +602,588 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 5,273,750 | 5,804,912 | +531,162 | 0.00 | 0.00 | -0.00 | buy |
| Sofinnova Investments, Inc. | 0 | 527,099 | +527,099 | 0.00 | 0.27 | +0.27 | buy |
| STATE STREET CORP | 1,621,260 | 2,069,884 | +448,624 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 1,950,301 | 2,359,824 | +409,523 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 133,508 | 502,366 | +368,858 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,812,039 | 2,165,534 | +353,495 | 0.00 | 0.00 | +0.00 | buy |
| STEMPOINT CAPITAL LP | 276,884 | 565,140 | +288,256 | 0.76 | 1.17 | +0.41 | buy |
| JANE STREET GROUP, LLC | 0 | 263,235 | +263,235 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 509,780 | 771,248 | +261,468 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 98,416 | 344,401 | +245,985 | 0.00 | 0.01 | +0.00 | buy |
| Qube Research & Technologies Ltd | 167,106 | 412,873 | +245,767 | 0.00 | 0.01 | +0.00 | buy |
| FEDERATED HERMES, INC. | 212,379 | 457,412 | +245,033 | 0.01 | 0.01 | +0.00 | buy |
| HighVista Strategies LLC | 0 | 238,812 | +238,812 | 0.00 | 0.74 | +0.74 | buy |
| XTX Topco Ltd | 0 | 189,673 | +189,673 | 0.00 | 0.06 | +0.06 | buy |
| TWO SIGMA ADVISERS, LP | 143,000 | 328,401 | +185,401 | 0.00 | 0.01 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 19,900 | 192,500 | +172,600 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 0 | 161,700 | +161,700 | 0.00 | 0.00 | +0.00 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0 | 153,363 | +153,363 | 0.00 | 0.01 | +0.01 | buy |
| Atom Investors LP | 0 | 139,422 | +139,422 | 0.00 | 0.13 | +0.13 | buy |
| Nuveen, LLC | 160,419 | 283,948 | +123,529 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 822,237 | 937,764 | +115,527 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 234,673 | 344,968 | +110,295 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 98,838 | +98,838 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 90,172 | +90,172 | 0.00 | 0.01 | +0.01 | buy |
| Squarepoint Ops LLC | 0 | 76,562 | +76,562 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4,331 | 79,090 | +74,759 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 13,875 | 84,144 | +70,269 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 68,892 | +68,892 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 645,185 | 712,990 | +67,805 | 0.00 | 0.00 | -0.00 | buy |
| Campbell & CO Investment Adviser LLC | 24,482 | 78,763 | +54,281 | 0.03 | 0.05 | +0.02 | buy |
| SEI INVESTMENTS CO | 0 | 52,856 | +52,856 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 93,691 | 146,309 | +52,618 | 0.00 | 0.00 | +0.00 | buy |
| SummitTX Capital, L.P. | 168,000 | 218,399 | +50,399 | 0.09 | 0.08 | -0.01 | buy |
| GREAT POINT PARTNERS LLC | 1,700,000 | 1,750,000 | +50,000 | 9.65 | 6.85 | -2.79 | buy |
| Numerai GP LLC | 67,153 | 112,648 | +45,495 | 0.13 | 0.16 | +0.04 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 35,409 | +35,409 | 0.00 | 0.07 | +0.07 | buy |
| Bank of New York Mellon Corp | 182,956 | 217,347 | +34,391 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,906 | 35,877 | +33,971 | 0.00 | 0.00 | +0.00 | buy |
| Patient Square Capital LP | 316,312 | 350,000 | +33,688 | 1.15 | 0.91 | -0.24 | buy |
| JPMORGAN CHASE & CO | 35,844 | 66,547 | +30,703 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 0 | 30,543 | +30,543 | 0.00 | 0.03 | +0.03 | buy |
| Integrated Quantitative Investments LLC | 0 | 27,234 | +27,234 | 0.00 | 0.07 | +0.07 | buy |
| Aquatic Capital Management LLC | 0 | 24,352 | +24,352 | 0.00 | 0.01 | +0.01 | buy |
| ADAR1 Capital Management, LLC | 866,202 | 890,356 | +24,154 | 1.17 | 0.80 | -0.36 | buy |
| Arizona State Retirement System | 0 | 22,914 | +22,914 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 22,402 | +22,402 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 20,307 | +20,307 | 0.00 | 0.07 | +0.07 | buy |
| Engineers Gate Manager LP | 0 | 18,358 | +18,358 | 0.00 | 0.00 | +0.00 | buy |
| Rafferty Asset Management, LLC | 0 | 17,673 | +17,673 | 0.00 | 0.00 | +0.00 | buy |
| KLP KAPITALFORVALTNING AS | 0 | 17,400 | +17,400 | 0.00 | 0.00 | +0.00 | buy |
| JUPITER ASSET MANAGEMENT LTD | 0 | 15,574 | +15,574 | 0.00 | 0.00 | +0.00 | buy |
| TFG Asset Management GP Ltd | 258,242 | 272,828 | +14,586 | 0.51 | 0.69 | +0.19 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 19,494 | 32,006 | +12,512 | 0.00 | 0.00 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 0 | 12,174 | +12,174 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 14,609 | 25,201 | +10,592 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 10,552 | +10,552 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 55,406 | 65,438 | +10,032 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 31,999 | 41,166 | +9,167 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 11,819 | 20,846 | +9,027 | 0.00 | 0.00 | -0.00 | buy |
| Persistent Asset Partners Ltd | 22,913 | 31,147 | +8,234 | 0.23 | 0.18 | -0.04 | buy |
| PROFUND ADVISORS LLC | 13,418 | 20,589 | +7,171 | 0.01 | 0.01 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 100,445 | 107,548 | +7,103 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 42,929 | 49,654 | +6,725 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 15,038 | 21,068 | +6,030 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 5,740 | +5,740 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 67,212 | 72,612 | +5,400 | 0.00 | 0.00 | -0.00 | buy |
| Valeo Financial Advisors, LLC | 10,000 | 15,000 | +5,000 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 19,262 | 23,752 | +4,490 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 68,877 | 73,224 | +4,347 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 3,727 | +3,727 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 366 | 3,859 | +3,493 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 23,790 | 26,988 | +3,198 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Trading LLC | 0 | 2,825 | +2,825 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 15,630 | 17,895 | +2,265 | 0.02 | 0.02 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 12,990 | 15,247 | +2,257 | 0.00 | 0.00 | +0.00 | buy |
| MEEDER ASSET MANAGEMENT INC | 0 | 2,099 | +2,099 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 3,447 | 5,337 | +1,890 | 0.00 | 0.00 | +0.00 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 10,401 | 12,226 | +1,825 | 0.01 | 0.01 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 6,590 | 8,095 | +1,505 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,794 | 7,203 | +1,409 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 1,381 | +1,381 | 0.00 | 0.00 | +0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 0 | 1,315 | +1,315 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 852 | +852 | 0.00 | 0.00 | +0.00 | buy |
| Westfuller Advisors, LLC | 0 | 819 | +819 | 0.00 | 0.00 | +0.00 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 1,512,500 | 1,513,148 | +648 | 0.34 | 0.29 | -0.05 | buy |
| NISA INVESTMENT ADVISORS, LLC | 285 | 922 | +637 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 98,657 | 99,274 | +617 | 0.00 | 0.00 | -0.00 | buy |
| AMALGAMATED BANK | 2,369 | 2,788 | +419 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 1,209 | 1,627 | +418 | 0.00 | 0.00 | +0.00 | buy |
| GUGGENHEIM CAPITAL LLC | 24,899 | 25,243 | +344 | 0.00 | 0.00 | -0.00 | buy |
| Arax Advisory Partners | 2,244 | 2,550 | +306 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 5 | 261 | +256 | 0.00 | 0.00 | +0.00 | buy |