| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARMISTICE CAPITAL, LLC | 639,193 | 1,118,925 | +479,732 | 0.09 | 0.23 | +0.14 | buy |
| Caligan Partners LP | 923,910 | 923,910 | 0 | 0.55 | 0.70 | +0.15 | hold |
| Affinity Asset Advisors, LLC | 0 | 707,338 | +707,338 | 0.00 | 0.42 | +0.42 | buy |
| Velan Capital Investment Management LP | 0 | 471,559 | +471,559 | 0.00 | 2.28 | +2.28 | buy |
| Stonepine Capital Management, LLC | 0 | 353,669 | +353,669 | 0.00 | 2.32 | +2.32 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 280,734 | 280,734 | 0 | 0.03 | 0.06 | +0.03 | hold |
| DAFNA Capital Management LLC | 0 | 173,451 | +173,451 | 0.00 | 0.33 | +0.33 | buy |
| VANGUARD GROUP INC | 225,210 | 138,194 | -87,016 | 0.00 | 0.00 | +0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 0 | 118,218 | +118,218 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 101,722 | +101,722 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 85,173 | +85,173 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 67,659 | 67,659 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TWO SIGMA ADVISERS, LP | 0 | 44,430 | +44,430 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 33,270 | +33,270 | 0.00 | 0.00 | +0.00 | buy |
| Sovran Advisors, LLC | 73,805 | 32,658 | -41,147 | 0.02 | 0.02 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 29,191 | 26,400 | -2,791 | 0.00 | 0.00 | +0.00 | sell |
| Mariner, LLC | 24,550 | 24,544 | -6 | 0.00 | 0.00 | +0.00 | sell |
| STATE STREET CORP | 20,581 | 23,481 | +2,900 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 71,990 | 23,123 | -48,867 | 0.00 | 0.00 | -0.00 | sell |
| OMERS ADMINISTRATION Corp | 0 | 22,600 | +22,600 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 20,031 | 20,024 | -7 | 0.00 | 0.00 | +0.00 | sell |
| HRT FINANCIAL LP | 0 | 17,356 | +17,356 | 0.00 | 0.00 | +0.00 | buy |
| Legacy Trust | 0 | 17,234 | +17,234 | 0.00 | 0.03 | +0.03 | buy |
| Walleye Capital LLC | 0 | 15,240 | +15,240 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 14,662 | +14,662 | 0.00 | 0.00 | +0.00 | buy |
| BECK MACK & OLIVER LLC | 0 | 12,000 | +12,000 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 12,000 | 12,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Quadrature Capital Ltd | 0 | 11,954 | +11,954 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 11,287 | +11,287 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,543 | 3,342 | +1,799 | 0.00 | 0.00 | +0.00 | buy |
| Capital Analysts, LLC | 1,500 | 1,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Fortitude Family Office, LLC | 0 | 608 | +608 | 0.00 | 0.00 | +0.00 | buy |
| Salomon & Ludwin, LLC | 290 | 290 | 0 | 0.00 | 0.00 | +0.00 | hold |
| New England Capital Financial Advisors LLC | 200 | 200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 0 | 175 | +175 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 124 | 110 | -14 | 0.00 | 0.00 | +0.00 | sell |
| Covestor Ltd | 54 | 54 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Optiver Holding B.V. | 31 | 31 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GROUP ONE TRADING LLC | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MAI Capital Management | 2 | 2 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BARCLAYS PLC | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Arax Advisory Partners | 9 | 0 | -9 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 3,337 | 0 | -3,337 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 2,065 | 0 | -2,065 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 142 | 0 | -142 | 0.00 | 0.00 | -0.00 | sell |