| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 4,377,900 | 6,830,300 | +2,452,400 | 0.33 | 0.26 | -0.06 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 697,653 | +697,653 | 0.00 | 0.00 | +0.00 | buy |
| WASATCH ADVISORS LP | 6,072,601 | 6,724,409 | +651,808 | 0.11 | 0.06 | -0.05 | buy |
| WELLS FARGO & COMPANY/MN | 36,306 | 523,619 | +487,313 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 425,096 | +425,096 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 1,677,642 | 1,990,824 | +313,182 | 0.00 | 0.00 | -0.00 | buy |
| Lynx1 Capital Management LP | 6,852,744 | 7,098,133 | +245,389 | 9.25 | 4.07 | -5.18 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 214,500 | +214,500 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 3,839,469 | 4,045,329 | +205,860 | 0.00 | 0.00 | -0.00 | buy |
| Atom Investors LP | 101,684 | 268,832 | +167,148 | 0.05 | 0.05 | +0.01 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0 | 129,900 | +129,900 | 0.00 | 0.01 | +0.01 | buy |
| AQR CAPITAL MANAGEMENT LLC | 13,288 | 140,532 | +127,244 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 70,325 | 193,910 | +123,585 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 757,852 | 872,770 | +114,918 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 108,664 | 212,003 | +103,339 | 0.01 | 0.01 | -0.00 | buy |
| Shay Capital LLC | 0 | 93,413 | +93,413 | 0.00 | 0.04 | +0.04 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 86,224 | +86,224 | 0.00 | 0.06 | +0.06 | buy |
| Man Group plc | 0 | 85,623 | +85,623 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 69,193 | 139,486 | +70,293 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,381,086 | 1,430,288 | +49,202 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 573,655 | 622,720 | +49,065 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 0 | 46,225 | +46,225 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 43,941 | +43,941 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Asset Management, L.P. | 196,466 | 236,855 | +40,389 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 0 | 40,100 | +40,100 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 27,675 | +27,675 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 3,345,973 | 3,370,880 | +24,907 | 0.00 | 0.00 | -0.00 | buy |
| Jain Global LLC | 0 | 24,203 | +24,203 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 30,150 | 53,606 | +23,456 | 0.00 | 0.00 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 19,595 | +19,595 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 18,187 | +18,187 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 16,009 | +16,009 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 14,429 | +14,429 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 13,347 | +13,347 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 13,034 | +13,034 | 0.00 | 0.00 | +0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 12,528 | +12,528 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 167,975 | 180,372 | +12,397 | 0.00 | 0.00 | -0.00 | buy |
| US BANCORP \DE\ | 56 | 11,600 | +11,544 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 6,742 | 18,096 | +11,354 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 132,832 | 141,986 | +9,154 | 0.00 | 0.00 | -0.00 | buy |
| HSBC HOLDINGS PLC | 19,359 | 25,487 | +6,128 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 495,043 | 499,768 | +4,725 | 0.00 | 0.00 | -0.00 | buy |
| D. E. Shaw & Co., Inc. | 76,479 | 79,275 | +2,796 | 0.00 | 0.00 | -0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 14,329 | 16,402 | +2,073 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 33,675 | 35,241 | +1,566 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 1,223,018 | 1,224,418 | +1,400 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 1,069 | +1,069 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 33,409 | 34,419 | +1,010 | 0.00 | 0.00 | -0.00 | buy |
| Cresset Asset Management, LLC | 25,000 | 25,978 | +978 | 0.00 | 0.00 | -0.00 | buy |
| Physician Wealth Advisors, Inc. | 0 | 472 | +472 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 21,573 | 22,021 | +448 | 0.00 | 0.00 | -0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,482 | 1,751 | +269 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 141,083 | 141,284 | +201 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 163 | +163 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT SECURITIES GROUP LLC | 0 | 155 | +155 | 0.00 | 0.00 | +0.00 | buy |
| CoreCap Advisors, LLC | 128 | 227 | +99 | 0.00 | 0.00 | -0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 52 | +52 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 12,695 | 12,745 | +50 | 0.00 | 0.00 | -0.00 | buy |
| SEI INVESTMENTS CO | 12,399 | 12,429 | +30 | 0.00 | 0.00 | -0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 40 | 70 | +30 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 4 | 33 | +29 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 2,352 | 2,375 | +23 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,744 | 5,744 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4,522 | 4,522 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 47,800 | 47,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,550,000 | 1,550,000 | 0 | 0.01 | 0.00 | -0.01 | hold |
| TANG CAPITAL MANAGEMENT LLC | 900,000 | 900,000 | 0 | 0.21 | 0.08 | -0.13 | hold |
| B. Riley Wealth Advisors, Inc. | 11,000 | 11,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| INTREPID FAMILY OFFICE LLC | 40,000 | 40,000 | 0 | 0.15 | 0.10 | -0.06 | hold |
| Bain Capital Life Sciences Investors, LLC | 1,111,910 | 1,111,910 | 0 | 0.47 | 0.26 | -0.21 | hold |
| Delta Investment Management, LLC | 20,000 | 20,000 | 0 | 0.01 | 0.01 | -0.01 | hold |
| Avion Wealth | 331 | 331 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Soleus Capital Management, L.P. | 6,978,942 | 6,978,942 | 0 | 1.90 | 0.88 | -1.03 | hold |
| SBI Securities Co., Ltd. | 150 | 150 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SYNTAX RESEARCH, INC. | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 85,000 | 85,000 | 0 | 0.18 | 0.07 | -0.10 | hold |
| Police & Firemen's Retirement System of New Jersey | 11,788 | 11,788 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 5,063 | 5,063 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 38,143 | 38,143 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 9,100 | 9,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FARALLON CAPITAL MANAGEMENT LLC | 28,000 | 28,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 2,029 | 2,029 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Caitong International Asset Management Co., Ltd | 15 | 0 | -15 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 29,905 | 29,468 | -437 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 15,768 | 15,316 | -452 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 14,967 | 14,239 | -728 | 0.01 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 1,878 | 1,081 | -797 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 18,277 | 17,322 | -955 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 28,880 | 26,100 | -2,780 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 13,361 | 10,438 | -2,923 | 0.00 | 0.00 | -0.00 | sell |
| Brooklyn Investment Group | 3,033 | 0 | -3,033 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 3,310 | 0 | -3,310 | 0.01 | 0.00 | -0.01 | sell |
| BANK OF MONTREAL /CAN/ | 24,450 | 20,800 | -3,650 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 10,974 | 7,275 | -3,699 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 20,283 | 16,223 | -4,060 | 0.00 | 0.00 | -0.00 | sell |
| SAMLYN CAPITAL, LLC | 3,019,458 | 3,015,139 | -4,319 | 0.17 | 0.08 | -0.09 | sell |
| SIMPLEX TRADING, LLC | 6,871 | 0 | -6,871 | 0.00 | 0.00 | -0.00 | sell |