| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| SAMLYN CAPITAL, LLC | 0 | 3,019,458 | +3,019,458 | 0.00 | 0.17 | +0.17 | buy |
| MORGAN STANLEY | 2,326,134 | 3,839,469 | +1,513,335 | 0.00 | 0.00 | +0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 520,000 | 1,550,000 | +1,030,000 | 0.01 | 0.01 | +0.00 | buy |
| BlackRock, Inc. | 4,890,935 | 5,558,851 | +667,916 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 334,081 | 757,852 | +423,771 | 0.00 | 0.00 | +0.00 | buy |
| WASATCH ADVISORS LP | 5,677,368 | 6,072,601 | +395,233 | 0.16 | 0.11 | -0.05 | buy |
| Soleus Capital Management, L.P. | 6,603,996 | 6,978,942 | +374,946 | 3.13 | 1.90 | -1.23 | buy |
| MILLENNIUM MANAGEMENT LLC | 21,848 | 360,125 | +338,277 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 700,000 | 900,000 | +200,000 | 0.29 | 0.21 | -0.07 | buy |
| Sio Capital Management, LLC | 0 | 155,000 | +155,000 | 0.00 | 0.16 | +0.16 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 23,000 | 137,360 | +114,360 | 0.00 | 0.01 | +0.01 | buy |
| Atom Investors LP | 0 | 101,684 | +101,684 | 0.00 | 0.05 | +0.05 | buy |
| JANE STREET GROUP, LLC | 69,451 | 152,774 | +83,323 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1,147,891 | 1,221,131 | +73,240 | 1.47 | 0.98 | -0.49 | buy |
| Verition Fund Management LLC | 0 | 69,628 | +69,628 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 505,852 | 573,655 | +67,803 | 0.00 | 0.00 | -0.00 | buy |
| WEXFORD CAPITAL LP | 55,231 | 118,331 | +63,100 | 0.08 | 0.11 | +0.03 | buy |
| ExodusPoint Capital Management, LP | 0 | 59,654 | +59,654 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 40,819 | +40,819 | 0.00 | 0.00 | +0.00 | buy |
| INTREPID FAMILY OFFICE LLC | 0 | 40,000 | +40,000 | 0.00 | 0.15 | +0.15 | buy |
| Mariner, LLC | 130,411 | 167,975 | +37,564 | 0.00 | 0.00 | -0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 192,364 | 227,147 | +34,783 | 0.05 | 0.04 | -0.01 | buy |
| GROUP ONE TRADING LLC | 0 | 32,883 | +32,883 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 185,941 | 218,365 | +32,424 | 0.00 | 0.00 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 23,176 | +23,176 | 0.00 | 0.01 | +0.01 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 19,744 | 42,533 | +22,789 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 22,693 | +22,693 | 0.00 | 0.00 | +0.00 | buy |
| Delta Investment Management, LLC | 0 | 20,000 | +20,000 | 0.00 | 0.01 | +0.01 | buy |
| M&T BANK CORP | 113,907 | 132,715 | +18,808 | 0.00 | 0.00 | -0.00 | buy |
| China Universal Asset Management Co., Ltd. | 0 | 14,967 | +14,967 | 0.00 | 0.01 | +0.01 | buy |
| ArrowMark Colorado Holdings LLC | 1,319,484 | 1,334,101 | +14,617 | 0.10 | 0.06 | -0.03 | buy |
| SEI INVESTMENTS CO | 0 | 12,399 | +12,399 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,369,676 | 1,381,086 | +11,410 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 122,373 | 132,832 | +10,459 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 26,917 | 36,306 | +9,389 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 11,079 | 20,283 | +9,204 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 62,175 | 70,325 | +8,150 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 25,779 | 33,409 | +7,630 | 0.00 | 0.00 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 103,026 | 109,825 | +6,799 | 0.01 | 0.01 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 6,742 | +6,742 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 489,820 | 495,043 | +5,223 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 64,546 | 69,193 | +4,647 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 95,649 | 100,015 | +4,366 | 0.00 | 0.00 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 482,929 | 486,366 | +3,437 | 0.00 | 0.00 | -0.00 | buy |
| Brooklyn Investment Group | 0 | 3,033 | +3,033 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 27,126 | 30,150 | +3,024 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 22,813 | 25,555 | +2,742 | 0.00 | 0.00 | -0.00 | buy |
| Point72 (DIFC) Ltd | 8,873 | 11,333 | +2,460 | 0.00 | 0.00 | -0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 0 | 2,352 | +2,352 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 186 | 1,878 | +1,692 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4,248 | 4,522 | +274 | 0.00 | 0.00 | -0.00 | buy |
| CoreCap Advisors, LLC | 0 | 128 | +128 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 38 | 56 | +18 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 4,377,900 | 4,377,900 | 0 | 0.46 | 0.33 | -0.13 | hold |
| Ameritas Investment Partners, Inc. | 5,744 | 5,744 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 47,800 | 47,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 4,878,000 | 4,878,000 | 0 | 0.32 | 0.23 | -0.09 | hold |
| B. Riley Wealth Advisors, Inc. | 11,000 | 11,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| LMR Partners LLP | 51,000 | 51,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 1,111,910 | 1,111,910 | 0 | 0.66 | 0.47 | -0.19 | hold |
| Cresset Asset Management, LLC | 25,000 | 25,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Avion Wealth | 331 | 331 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Corient Private Wealth LLC | 12,695 | 12,695 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SYNTAX RESEARCH, INC. | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | 85,000 | 85,000 | 0 | 0.21 | 0.18 | -0.03 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 5,063 | 5,063 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 9,100 | 9,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FARALLON CAPITAL MANAGEMENT LLC | 28,000 | 28,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 2,029 | 2,029 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ROTHSCHILD INVESTMENT LLC | 50 | 40 | -10 | 0.00 | 0.00 | -0.00 | sell |
| EARNED WEALTH ADVISORS, LLC | 54 | 0 | -54 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 15,842 | 15,768 | -74 | 0.00 | 0.00 | -0.00 | sell |
| Cape Investment Advisory, Inc. | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| FRANKLIN RESOURCES INC | 34,383 | 34,242 | -141 | 0.00 | 0.00 | -0.00 | sell |
| SUMMIT SECURITIES GROUP LLC | 143 | 0 | -143 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 165 | 0 | -165 | 0.00 | 0.00 | -0.00 | sell |
| GAMMA Investing LLC | 217 | 0 | -217 | 0.00 | 0.00 | -0.00 | sell |
| CAPTRUST FINANCIAL ADVISORS | 15,007 | 14,329 | -678 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 1,018 | 0 | -1,018 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 19,481 | 18,277 | -1,204 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 31,350 | 29,905 | -1,445 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN DEMPSEY CAPITAL MANAGEMENT LLC | 1,500 | 0 | -1,500 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 21,168 | 19,359 | -1,809 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 143,293 | 141,083 | -2,210 | 0.00 | 0.00 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 286,041 | 283,705 | -2,336 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 37,837 | 33,675 | -4,162 | 0.00 | 0.00 | -0.00 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 35,170 | 28,880 | -6,290 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 35,455 | 28,854 | -6,601 | 0.00 | 0.00 | -0.00 | sell |
| Cynosure Group, LLC | 10,007 | 0 | -10,007 | 0.01 | 0.00 | -0.01 | sell |
| AMERIPRISE FINANCIAL INC | 11,620 | 0 | -11,620 | 0.00 | 0.00 | -0.00 | sell |
| CORNERCAP INVESTMENT COUNSEL INC | 11,791 | 0 | -11,791 | 0.02 | 0.00 | -0.02 | sell |
| PRUDENTIAL FINANCIAL INC | 12,025 | 0 | -12,025 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 23,696 | 10,974 | -12,722 | 0.00 | 0.00 | -0.00 | sell |
| AIGEN INVESTMENT MANAGEMENT, LP | 14,344 | 0 | -14,344 | 0.02 | 0.00 | -0.02 | sell |
| STIFEL FINANCIAL CORP | 28,415 | 13,361 | -15,054 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 15,446 | 0 | -15,446 | 0.01 | 0.00 | -0.01 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 41,664 | 21,573 | -20,091 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 129,801 | 108,664 | -21,137 | 0.01 | 0.01 | -0.01 | sell |