| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAR1 Capital Management, LLC | 1,486,461 | 5,389,264 | +3,902,803 | 2.91 | 11.68 | +8.77 | buy |
| BlackRock, Inc. | 2,785,237 | 2,732,623 | -52,614 | 0.00 | 0.00 | +0.00 | sell |
| Madison Avenue Partners, LP | 0 | 2,691,465 | +2,691,465 | 0.00 | 2.40 | +2.40 | buy |
| VANGUARD GROUP INC | 2,566,321 | 2,631,648 | +65,327 | 0.00 | 0.00 | +0.00 | buy |
| Logos Global Management LP | 2,000,000 | 2,000,000 | 0 | 3.62 | 3.57 | -0.06 | hold |
| Nantahala Capital Management, LLC | 1,506,790 | 1,620,692 | +113,902 | 1.27 | 1.53 | +0.26 | buy |
| Western Standard LLC | 134,914 | 1,534,893 | +1,399,979 | 0.81 | 11.40 | +10.59 | buy |
| TANG CAPITAL MANAGEMENT LLC | 1,100,000 | 1,418,984 | +318,984 | 0.62 | 0.96 | +0.34 | buy |
| STATE STREET CORP | 1,302,539 | 1,384,254 | +81,715 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 1,263,130 | 1,297,383 | +34,253 | 0.02 | 0.02 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 1,018,734 | 1,018,734 | 0 | 0.25 | 0.34 | +0.09 | hold |
| GOLDMAN SACHS GROUP INC | 740,606 | 883,560 | +142,954 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 1,697,557 | 878,746 | -818,811 | 0.00 | 0.00 | -0.00 | sell |
| ALKEON CAPITAL MANAGEMENT LLC | 850,511 | 850,511 | 0 | 0.05 | 0.06 | +0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 806,185 | 829,297 | +23,112 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 1,224,139 | 654,030 | -570,109 | 0.03 | 0.02 | -0.01 | sell |
| Redmile Group, LLC | 552,506 | 552,506 | 0 | 0.53 | 0.79 | +0.25 | hold |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 524,340 | +524,340 | 0.00 | 0.03 | +0.03 | buy |
| JANUS HENDERSON GROUP PLC | 0 | 472,392 | +472,392 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 276,060 | 332,815 | +56,755 | 0.20 | 0.25 | +0.05 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 318,400 | +318,400 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 155,612 | 295,477 | +139,865 | 0.00 | 0.00 | +0.00 | buy |
| Rangeley Capital, LLC | 408,234 | 285,400 | -122,834 | 4.69 | 4.78 | +0.09 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 241,923 | 283,403 | +41,480 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 290,011 | 273,123 | -16,888 | 0.00 | 0.00 | +0.00 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 128,103 | 265,707 | +137,604 | 0.01 | 0.01 | +0.01 | buy |
| Newtyn Management, LLC | 0 | 246,857 | +246,857 | 0.00 | 0.50 | +0.50 | buy |
| DEUTSCHE BANK AG\ | 22,962 | 211,637 | +188,675 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 41,301 | 171,763 | +130,462 | 0.00 | 0.01 | +0.01 | buy |
| FMR LLC | 441,540 | 164,271 | -277,269 | 0.00 | 0.00 | -0.00 | sell |
| RBF Capital, LLC | 170,014 | 150,000 | -20,014 | 0.11 | 0.10 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 146,600 | +146,600 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 38,295 | 132,301 | +94,006 | 0.00 | 0.00 | +0.00 | buy |
| DAFNA Capital Management LLC | 130,316 | 130,316 | 0 | 0.38 | 0.48 | +0.10 | hold |
| TFG Asset Management GP Ltd | 183,000 | 128,000 | -55,000 | 0.60 | 0.31 | -0.29 | sell |
| Man Group plc | 34,013 | 121,545 | +87,532 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 59,860 | 121,130 | +61,270 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 121,849 | 113,665 | -8,184 | 0.00 | 0.00 | +0.00 | sell |
| Bank of New York Mellon Corp | 97,755 | 109,349 | +11,594 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 104,878 | +104,878 | 0.00 | 0.03 | +0.03 | buy |
| UBS Group AG | 92,429 | 102,773 | +10,344 | 0.00 | 0.00 | +0.00 | buy |
| Assenagon Asset Management S.A. | 64,937 | 101,297 | +36,360 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 98,641 | +98,641 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 70,512 | 90,735 | +20,223 | 0.03 | 0.03 | +0.01 | buy |
| Nebula Research & Development LLC | 115,420 | 90,406 | -25,014 | 0.11 | 0.10 | -0.01 | sell |
| MONIMUS CAPITAL MANAGEMENT, LP | 84,055 | 90,396 | +6,341 | 0.73 | 0.97 | +0.24 | buy |
| Nuveen, LLC | 3,947,455 | 75,855 | -3,871,600 | 0.03 | 0.00 | -0.03 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 0 | 71,924 | +71,924 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 22,136 | 70,650 | +48,514 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 65,844 | 70,149 | +4,305 | 0.02 | 0.01 | -0.01 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 0 | 64,581 | +64,581 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 8,254 | 61,743 | +53,489 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 61,455 | +61,455 | 0.00 | 0.06 | +0.06 | buy |
| JANE STREET GROUP, LLC | 46,945 | 57,281 | +10,336 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 27,480 | 55,570 | +28,090 | 0.01 | 0.02 | +0.01 | buy |
| Rafferty Asset Management, LLC | 55,332 | 54,294 | -1,038 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 48,121 | 54,145 | +6,024 | 0.03 | 0.03 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 0 | 53,877 | +53,877 | 0.00 | 0.00 | +0.00 | buy |
| HighVista Strategies LLC | 52,107 | 52,618 | +511 | 0.20 | 0.26 | +0.05 | buy |
| RHUMBLINE ADVISERS | 44,669 | 51,815 | +7,146 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 43,227 | 48,415 | +5,188 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 2,600,457 | 47,654 | -2,552,803 | 0.00 | 0.00 | -0.00 | sell |
| Quadrature Capital Ltd | 28,871 | 47,000 | +18,129 | 0.01 | 0.01 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 81,936 | 46,599 | -35,337 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 33,266 | 43,395 | +10,129 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 41,709 | +41,709 | 0.00 | 0.00 | +0.00 | buy |
| SummitTX Capital, L.P. | 30,884 | 40,000 | +9,116 | 0.01 | 0.02 | +0.01 | buy |
| Qube Research & Technologies Ltd | 273,342 | 38,677 | -234,665 | 0.00 | 0.00 | -0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 115,518 | 37,891 | -77,627 | 0.03 | 0.01 | -0.01 | sell |
| DIMENSIONAL FUND ADVISORS LP | 36,636 | 36,636 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Caption Management, LLC | 106,981 | 36,078 | -70,903 | 0.05 | 0.04 | -0.01 | sell |
| CITIGROUP INC | 71,757 | 34,379 | -37,378 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 28,510 | 27,810 | -700 | 0.00 | 0.00 | +0.00 | sell |
| Polymer Capital Management (US) LLC | 11,541 | 27,181 | +15,640 | 0.04 | 0.06 | +0.02 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 0 | 26,103 | +26,103 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 13,234 | 25,958 | +12,724 | 0.01 | 0.03 | +0.02 | buy |
| Creative Planning | 17,278 | 24,226 | +6,948 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 49,694 | 23,031 | -26,663 | 0.02 | 0.01 | -0.01 | sell |
| CITADEL ADVISORS LLC | 191,609 | 22,898 | -168,711 | 0.00 | 0.00 | -0.00 | sell |
| ALPS ADVISORS INC | 29,736 | 21,949 | -7,787 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 16,778 | 21,945 | +5,167 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 21,849 | +21,849 | 0.00 | 0.00 | +0.00 | buy |
| Erste Asset Management GmbH | 20,700 | 20,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MetLife Investment Management, LLC | 18,098 | 19,749 | +1,651 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 21,122 | 19,099 | -2,023 | 0.00 | 0.00 | +0.00 | sell |
| TWO SIGMA ADVISERS, LP | 119,500 | 17,100 | -102,400 | 0.00 | 0.00 | -0.00 | sell |
| MARTINGALE ASSET MANAGEMENT L P | 0 | 13,858 | +13,858 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 233,203 | 13,705 | -219,498 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 62,372 | 13,522 | -48,850 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 11,463 | 12,451 | +988 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 18,989 | 12,354 | -6,635 | 0.03 | 0.03 | -0.00 | sell |
| Engineers Gate Manager LP | 106,933 | 12,037 | -94,896 | 0.02 | 0.00 | -0.02 | sell |
| PROFUND ADVISORS LLC | 11,569 | 11,421 | -148 | 0.01 | 0.01 | +0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 2,916 | 10,616 | +7,700 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN FINANCIAL GROUP INC | 10,105 | 10,105 | 0 | 0.04 | 0.05 | +0.01 | hold |
| US BANCORP \DE\ | 16 | 9,864 | +9,848 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 0 | 9,400 | +9,400 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 17,061 | 9,349 | -7,712 | 0.12 | 0.07 | -0.04 | sell |
| Police & Firemen's Retirement System of New Jersey | 6,365 | 8,257 | +1,892 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 8,136 | 8,157 | +21 | 0.01 | 0.01 | +0.00 | buy |