| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Ikarian Capital, LLC | 211,538 | 211,538 | 0 | 0.40 | 0.20 | -0.20 | hold |
| Dauntless Investment Group, LLC | 0 | 196,592 | +196,592 | 0.00 | 3.65 | +3.65 | buy |
| SummitTX Capital, L.P. | 64,795 | 100,300 | +35,505 | 0.03 | 0.02 | -0.01 | buy |
| Velan Capital Investment Management LP | 0 | 84,849 | +84,849 | 0.00 | 0.35 | +0.35 | buy |
| Woodline Partners LP | 79,582 | 79,582 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MILLENNIUM MANAGEMENT LLC | 74,817 | 76,247 | +1,430 | 0.00 | 0.00 | -0.00 | buy |
| Aberdeen Group plc | 75,000 | 75,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Soleus Capital Management, L.P. | 25,000 | 72,730 | +47,730 | 0.02 | 0.02 | +0.00 | buy |
| Centiva Capital, LP | 12,053 | 60,000 | +47,947 | 0.01 | 0.02 | +0.01 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 59,838 | 59,838 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Stonepine Capital Management, LLC | 78,189 | 53,460 | -24,729 | 0.89 | 0.31 | -0.58 | sell |
| AIGH Capital Management LLC | 49,323 | 51,000 | +1,677 | 0.21 | 0.07 | -0.14 | buy |
| Birchview Capital, LP | 0 | 20,000 | +20,000 | 0.00 | 0.08 | +0.08 | buy |
| GAMMA Investing LLC | 2,084 | 1,720 | -364 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 1,666 | 1,521 | -145 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 0 | 1,300 | +1,300 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 247 | 2 | -245 | 0.00 | 0.00 | -0.00 | sell |
| Resolute Capital Asset Partners LLC | 30,000 | 0 | -30,000 | 0.21 | 0.00 | -0.21 | sell |
| Simplify Asset Management Inc. | 17,448 | 0 | -17,448 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 58,230 | 0 | -58,230 | 0.06 | 0.00 | -0.06 | sell |