| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MPM BioImpact LLC | 0 | 1,313,104 | +1,313,104 | 0.00 | 2.84 | +2.84 | buy |
| Cormorant Asset Management, LP | 500,000 | 1,600,000 | +1,100,000 | 0.29 | 1.52 | +1.23 | buy |
| Rubric Capital Management LP | 0 | 1,029,101 | +1,029,101 | 0.00 | 0.23 | +0.23 | buy |
| Aberdeen Group plc | 0 | 1,002,659 | +1,002,659 | 0.00 | 0.02 | +0.02 | buy |
| LEVIN CAPITAL STRATEGIES, L.P. | 467,627 | 1,164,601 | +696,974 | 0.47 | 1.56 | +1.08 | buy |
| Octagon Capital Advisors LP | 0 | 625,000 | +625,000 | 0.00 | 1.07 | +1.07 | buy |
| K2 PRINCIPAL FUND, L.P. | 0 | 485,355 | +485,355 | 0.00 | 0.93 | +0.93 | buy |
| Nicholas Investment Partners, LP | 172,018 | 611,737 | +439,719 | 0.16 | 0.79 | +0.63 | buy |
| Janney Montgomery Scott LLC | 27,158 | 448,669 | +421,511 | 0.00 | 0.02 | +0.02 | buy |
| ARDSLEY ADVISORY PARTNERS LP | 0 | 325,000 | +325,000 | 0.00 | 0.95 | +0.95 | buy |
| BANK OF AMERICA CORP /DE/ | 160,958 | 444,703 | +283,745 | 0.00 | 0.00 | +0.00 | buy |
| Advisor Resource Council | 0 | 249,230 | +249,230 | 0.00 | 0.25 | +0.25 | buy |
| Lisanti Capital Growth, LLC | 0 | 193,830 | +193,830 | 0.00 | 0.73 | +0.73 | buy |
| ExodusPoint Capital Management, LP | 24,628 | 197,535 | +172,907 | 0.00 | 0.03 | +0.03 | buy |
| Epoch Investment Partners, Inc. | 0 | 118,982 | +118,982 | 0.00 | 0.01 | +0.01 | buy |
| Quinn Opportunity Partners LLC | 0 | 111,628 | +111,628 | 0.00 | 0.10 | +0.10 | buy |
| MARSHALL WACE, LLP | 52,906 | 156,635 | +103,729 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 623,281 | 706,787 | +83,506 | 0.00 | 0.00 | +0.00 | buy |
| PEREGRINE CAPITAL MANAGEMENT LLC | 423,561 | 501,821 | +78,260 | 0.13 | 0.21 | +0.08 | buy |
| First Turn Management, LLC | 593,291 | 669,010 | +75,719 | 1.12 | 1.70 | +0.58 | buy |
| CastleKnight Management LP | 0 | 65,300 | +65,300 | 0.00 | 0.09 | +0.09 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 0 | 56,553 | +56,553 | 0.00 | 0.03 | +0.03 | buy |
| Matisse Capital | 0 | 55,714 | +55,714 | 0.00 | 0.37 | +0.37 | buy |
| Squarepoint Ops LLC | 24,777 | 76,824 | +52,047 | 0.00 | 0.00 | +0.00 | buy |
| Coastal Bridge Advisors, LLC | 0 | 46,750 | +46,750 | 0.00 | 0.05 | +0.05 | buy |
| FAS Wealth Partners, Inc. | 94,705 | 139,535 | +44,830 | 0.08 | 0.14 | +0.06 | buy |
| Trexquant Investment LP | 56,563 | 100,769 | +44,206 | 0.01 | 0.01 | +0.01 | buy |
| Knights of Columbus Asset Advisors LLC | 0 | 43,144 | +43,144 | 0.00 | 0.04 | +0.04 | buy |
| ALLIANCEBERNSTEIN L.P. | 3,880,734 | 3,922,805 | +42,071 | 0.01 | 0.02 | +0.00 | buy |
| SCHULHOFF & CO INC | 0 | 40,500 | +40,500 | 0.00 | 0.23 | +0.23 | buy |
| AssuredPartners Investment Advisors, LLC | 29,611 | 69,111 | +39,500 | 0.06 | 0.17 | +0.11 | buy |
| WEXFORD CAPITAL LP | 369,497 | 408,551 | +39,054 | 1.00 | 1.34 | +0.34 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 36,342 | 72,753 | +36,411 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 69,376 | 104,110 | +34,734 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 33,000 | +33,000 | 0.00 | 0.10 | +0.10 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 171,385 | 204,201 | +32,816 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 247,314 | 279,840 | +32,526 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 12,306 | 44,092 | +31,786 | 0.00 | 0.02 | +0.02 | buy |
| Kestra Advisory Services, LLC | 0 | 31,479 | +31,479 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 286,846 | 317,347 | +30,501 | 0.00 | 0.00 | +0.00 | buy |
| Harbour Capital Advisors, LLC | 0 | 28,650 | +28,650 | 0.00 | 0.09 | +0.09 | buy |
| Allspring Global Investments Holdings, LLC | 344,171 | 368,556 | +24,385 | 0.01 | 0.01 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 23,845 | +23,845 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 3,464,952 | 3,488,293 | +23,341 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,238,156 | 1,260,477 | +22,321 | 0.00 | 0.00 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 21,700 | +21,700 | 0.00 | 0.00 | +0.00 | buy |
| DIKER MANAGEMENT LLC | 0 | 21,000 | +21,000 | 0.00 | 0.32 | +0.32 | buy |
| Capula Management Ltd | 0 | 20,791 | +20,791 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 18,547 | +18,547 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 41,701 | 59,647 | +17,946 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 32,218 | 49,647 | +17,429 | 0.03 | 0.03 | +0.00 | buy |
| AlphaQuest LLC | 2,111 | 18,064 | +15,953 | 0.00 | 0.02 | +0.02 | buy |
| OPPENHEIMER & CO INC | 0 | 15,014 | +15,014 | 0.00 | 0.00 | +0.00 | buy |
| Everstar Asset Management, LLC | 0 | 15,000 | +15,000 | 0.00 | 0.09 | +0.09 | buy |
| FOSTER & MOTLEY INC | 0 | 14,780 | +14,780 | 0.00 | 0.01 | +0.01 | buy |
| Gotham Asset Management, LLC | 0 | 13,029 | +13,029 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 15,438 | 27,681 | +12,243 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 19,526 | 31,551 | +12,025 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 11,116 | +11,116 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 10,974 | +10,974 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 10,920 | +10,920 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 38,050 | 48,480 | +10,430 | 0.00 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 19,988 | 29,949 | +9,961 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 432,603 | 442,514 | +9,911 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 17,574 | 27,452 | +9,878 | 0.01 | 0.03 | +0.02 | buy |
| NORTHERN TRUST CORP | 478,153 | 487,043 | +8,890 | 0.00 | 0.00 | +0.00 | buy |
| DAFNA Capital Management LLC | 88,790 | 95,290 | +6,500 | 0.24 | 0.34 | +0.10 | buy |
| RHUMBLINE ADVISERS | 65,163 | 69,766 | +4,603 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 0 | 3,910 | +3,910 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 21,408 | 24,993 | +3,585 | 0.00 | 0.00 | +0.00 | buy |
| ANTIPODES PARTNERS Ltd | 0 | 2,943 | +2,943 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 30,206 | 33,119 | +2,913 | 0.00 | 0.00 | +0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 608 | 3,091 | +2,483 | 0.00 | 0.01 | +0.00 | buy |
| Engineers Gate Manager LP | 16,359 | 18,583 | +2,224 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 35,908 | 37,973 | +2,065 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 130,238 | 132,213 | +1,975 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 19,918 | 21,759 | +1,841 | 0.00 | 0.00 | +0.00 | buy |
| Capital Analysts, LLC | 0 | 1,300 | +1,300 | 0.00 | 0.00 | +0.00 | buy |
| Brooklyn Investment Group | 47 | 1,343 | +1,296 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 917 | 2,013 | +1,096 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 31,112 | 32,203 | +1,091 | 0.00 | 0.00 | +0.00 | buy |
| Heritage Wealth Advisors | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Future Financial Wealth Managment LLC | 0 | 1,000 | +1,000 | 0.00 | 0.01 | +0.01 | buy |
| Versant Capital Management, Inc | 0 | 622 | +622 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 65 | 627 | +562 | 0.00 | 0.00 | +0.00 | buy |
| Cresset Asset Management, LLC | 27,752 | 28,252 | +500 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 2,041 | 2,488 | +447 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 246 | 536 | +290 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 76 | 267 | +191 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 70 | +70 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 45 | 105 | +60 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 45 | +45 | 0.00 | 0.00 | +0.00 | buy |
| Stephens Consulting, LLC | 0 | 30 | +30 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 17 | 38 | +21 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 21 | +21 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 3,239 | 3,252 | +13 | 0.00 | 0.00 | +0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 10,514,657 | 10,514,657 | 0 | 2.11 | 2.62 | +0.51 | hold |
| ORBIMED ADVISORS LLC | 8,288,510 | 8,288,510 | 0 | 1.82 | 2.50 | +0.69 | hold |
| Ameritas Investment Partners, Inc. | 4,821 | 4,821 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 36,988 | 36,988 | 0 | 0.00 | 0.00 | +0.00 | hold |