| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARK Investment Management LLC | 10,165,400 | 10,182,590 | +17,190 | 3.46 | 3.63 | +0.17 | buy |
| BlackRock, Inc. | 2,613,539 | 6,066,358 | +3,452,819 | 0.00 | 0.01 | +0.00 | buy |
| Capital International Investors | 6,073,118 | 5,593,747 | -479,371 | 0.04 | 0.05 | +0.01 | sell |
| T. Rowe Price Investment Management, Inc. | 3,798,103 | 3,683,026 | -115,077 | 0.09 | 0.11 | +0.03 | sell |
| STATE STREET CORP | 2,411,262 | 3,270,596 | +859,334 | 0.00 | 0.01 | +0.00 | buy |
| UBS Group AG | 2,071,892 | 2,843,577 | +771,685 | 0.02 | 0.03 | +0.01 | buy |
| Orbis Allan Gray Ltd | 1,562,932 | 2,764,532 | +1,201,600 | 0.30 | 0.65 | +0.35 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 2,539,889 | 2,414,838 | -125,051 | 0.06 | 0.07 | +0.01 | sell |
| Nikko Asset Management Americas, Inc. | 2,539,889 | 2,414,271 | -125,618 | 1.11 | 1.17 | +0.06 | sell |
| VANGUARD GROUP INC | 1,769,709 | 2,298,089 | +528,380 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,045,904 | 2,071,883 | +1,025,979 | 0.00 | 0.01 | +0.00 | buy |
| FMR LLC | 1,940,545 | 1,929,154 | -11,391 | 0.00 | 0.01 | +0.00 | sell |
| NEA Management Company, LLC | 1,587,854 | 1,587,854 | 0 | 4.16 | 5.81 | +1.65 | hold |
| TWO SIGMA INVESTMENTS, LP | 1,189,159 | 1,545,966 | +356,807 | 0.09 | 0.14 | +0.05 | buy |
| BANK OF AMERICA CORP /DE/ | 1,386,770 | 1,448,415 | +61,645 | 0.00 | 0.01 | +0.00 | buy |
| EcoR1 Capital, LLC | 1,389,276 | 1,389,276 | 0 | 2.81 | 4.00 | +1.20 | hold |
| TWO SIGMA ADVISERS, LP | 797,200 | 1,344,700 | +547,500 | 0.06 | 0.13 | +0.07 | buy |
| SR ONE CAPITAL MANAGEMENT, LP | 1,048,951 | 1,048,951 | 0 | 9.17 | 11.06 | +1.89 | hold |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,952,751 | 964,690 | -988,061 | 0.02 | 0.01 | -0.01 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 713,539 | 933,204 | +219,665 | 0.00 | 0.01 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 937,145 | 917,712 | -19,433 | 0.01 | 0.01 | +0.00 | sell |
| LOOMIS SAYLES & CO L P | 909,792 | 856,887 | -52,905 | 0.04 | 0.05 | +0.01 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 291,016 | 769,945 | +478,929 | 0.02 | 0.06 | +0.04 | buy |
| NORTHERN TRUST CORP | 237,648 | 761,115 | +523,467 | 0.00 | 0.01 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 735,600 | +735,600 | 0.00 | 0.04 | +0.04 | buy |
| MORGAN STANLEY | 1,299,982 | 511,380 | -788,602 | 0.00 | 0.00 | -0.00 | sell |
| Versant Venture Management, LLC | 498,558 | 498,558 | 0 | 28.18 | 29.52 | +1.35 | hold |
| BANK OF MONTREAL /CAN/ | 0 | 493,743 | +493,743 | 0.00 | 0.01 | +0.01 | buy |
| Vestmark Advisory Solutions, Inc. | 225,306 | 484,975 | +259,669 | 0.20 | 0.34 | +0.14 | buy |
| NORGES BANK | 456,060 | 406,487 | -49,573 | 0.00 | 0.00 | +0.00 | sell |
| BARCLAYS PLC | 89,626 | 380,623 | +290,997 | 0.00 | 0.01 | +0.01 | buy |
| Contrarius Group Holdings Ltd | 331,972 | 374,954 | +42,982 | 0.77 | 1.03 | +0.26 | buy |
| Jump Financial, LLC | 0 | 356,306 | +356,306 | 0.00 | 0.22 | +0.22 | buy |
| ROYAL BANK OF CANADA | 142,696 | 337,138 | +194,442 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 295,987 | 321,094 | +25,107 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 77,702 | 301,959 | +224,257 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 218,060 | 262,089 | +44,029 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 246,086 | 235,920 | -10,166 | 0.01 | 0.01 | +0.00 | sell |
| WELLS FARGO & COMPANY/MN | 265,526 | 235,740 | -29,786 | 0.00 | 0.00 | +0.00 | sell |
| TD ASSET MANAGEMENT INC | 242,320 | 228,416 | -13,904 | 0.01 | 0.01 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 147,328 | 220,600 | +73,272 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 65,195 | 195,602 | +130,407 | 0.26 | 0.85 | +0.58 | buy |
| LPL Financial LLC | 185,458 | 194,579 | +9,121 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 0 | 184,853 | +184,853 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 157,100 | 156,400 | -700 | 0.00 | 0.00 | +0.00 | sell |
| Woodline Partners LP | 136,483 | 149,267 | +12,784 | 0.03 | 0.04 | +0.01 | buy |
| McElhenny Sheffield Capital Management, LLC | 0 | 136,000 | +136,000 | 0.00 | 0.03 | +0.03 | buy |
| Legal & General Group Plc | 81,155 | 129,567 | +48,412 | 0.00 | 0.00 | +0.00 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 126,600 | 127,500 | +900 | 0.00 | 0.01 | +0.00 | buy |
| CITIGROUP INC | 205,648 | 126,892 | -78,756 | 0.01 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 0 | 123,893 | +123,893 | 0.00 | 0.01 | +0.01 | buy |
| Rockefeller Capital Management L.P. | 90,503 | 115,356 | +24,853 | 0.01 | 0.01 | +0.00 | buy |
| Rafferty Asset Management, LLC | 146,032 | 114,348 | -31,684 | 0.02 | 0.02 | -0.00 | sell |
| Private Advisor Group, LLC | 108,418 | 111,949 | +3,531 | 0.02 | 0.03 | +0.01 | buy |
| Reynders McVeigh Capital Management, LLC | 101,773 | 111,431 | +9,658 | 0.19 | 0.27 | +0.08 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 75,333 | 105,398 | +30,065 | 0.01 | 0.01 | +0.00 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 95,617 | 103,628 | +8,011 | 0.00 | 0.00 | +0.00 | buy |
| Integral Health Asset Management, LLC | 150,000 | 100,000 | -50,000 | 0.57 | 0.45 | -0.11 | sell |
| RAYMOND JAMES FINANCIAL INC | 86,666 | 97,573 | +10,907 | 0.00 | 0.00 | +0.00 | buy |
| Baker Chad R | 93,205 | 93,205 | 0 | 0.65 | 0.84 | +0.20 | hold |
| EverSource Wealth Advisors, LLC | 84,880 | 92,943 | +8,063 | 0.16 | 0.20 | +0.05 | buy |
| Capital International Sarl | 102,942 | 91,517 | -11,425 | 0.08 | 0.09 | +0.01 | sell |
| ALLIANCEBERNSTEIN L.P. | 0 | 86,620 | +86,620 | 0.00 | 0.00 | +0.00 | buy |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | 93,574 | 83,120 | -10,454 | 0.27 | 0.32 | +0.04 | sell |
| VAN ECK ASSOCIATES CORP | 83,010 | 83,010 | 0 | 0.00 | 0.00 | +0.00 | hold |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 94,100 | 82,607 | -11,493 | 0.01 | 0.01 | +0.00 | sell |
| Slow Capital, Inc. | 65,244 | 75,396 | +10,152 | 0.30 | 0.45 | +0.15 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 69,742 | 74,907 | +5,165 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 583,733 | 70,093 | -513,640 | 0.02 | 0.00 | -0.02 | sell |
| CONGRESS ASSET MANAGEMENT CO | 68,302 | 68,404 | +102 | 0.02 | 0.02 | +0.01 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 68,058 | 67,942 | -116 | 0.00 | 0.00 | +0.00 | sell |
| Invesco Ltd. | 27,957 | 66,648 | +38,691 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 27,363 | 66,367 | +39,004 | 0.00 | 0.00 | +0.00 | buy |
| Del-Sette Capital Management, LLC | 0 | 63,843 | +63,843 | 0.00 | 2.16 | +2.16 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 74,882 | 62,574 | -12,308 | 0.00 | 0.00 | +0.00 | sell |
| CAPITAL INTERNATIONAL LTD /CA/ | 72,063 | 61,552 | -10,511 | 0.11 | 0.11 | +0.01 | sell |
| LAZARD ASSET MANAGEMENT LLC | 63,690 | 59,333 | -4,357 | 0.00 | 0.00 | +0.00 | sell |
| GUGGENHEIM CAPITAL LLC | 96,266 | 58,488 | -37,778 | 0.03 | 0.02 | -0.01 | sell |
| Green Alpha Advisors, LLC | 57,361 | 58,463 | +1,102 | 2.08 | 2.72 | +0.63 | buy |
| BENJAMIN EDWARDS INC | 50,915 | 57,760 | +6,845 | 0.02 | 0.04 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 8,247 | 57,260 | +49,013 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 43,663 | 52,035 | +8,372 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 52,350 | 51,565 | -785 | 0.00 | 0.01 | +0.00 | sell |
| Curi Capital, LLC | 47,230 | 51,417 | +4,187 | 0.04 | 0.05 | +0.01 | buy |
| PHILADELPHIA TRUST CO | 0 | 50,250 | +50,250 | 0.00 | 0.19 | +0.19 | buy |
| State of New Jersey Common Pension Fund D | 41,540 | 50,185 | +8,645 | 0.01 | 0.01 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 49,339 | +49,339 | 0.00 | 0.01 | +0.01 | buy |
| HighTower Advisors, LLC | 33,033 | 49,196 | +16,163 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 57,919 | 48,015 | -9,904 | 0.00 | 0.00 | +0.00 | sell |
| Cambridge Investment Research Advisors, Inc. | 39,189 | 45,467 | +6,278 | 0.00 | 0.01 | +0.00 | buy |
| Privium Fund Management B.V. | 60,097 | 44,700 | -15,397 | 0.53 | 0.47 | -0.07 | sell |
| Palo Alto Investors LP | 0 | 44,625 | +44,625 | 0.00 | 0.46 | +0.46 | buy |
| STIFEL FINANCIAL CORP | 39,019 | 42,950 | +3,931 | 0.00 | 0.00 | +0.00 | buy |
| Koss-Olinger Consulting, LLC | 32,512 | 42,197 | +9,685 | 0.09 | 0.17 | +0.08 | buy |
| DekaBank Deutsche Girozentrale | 40,745 | 40,745 | 0 | 0.01 | 0.00 | -0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 10,903 | 39,313 | +28,410 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 39,161 | +39,161 | 0.00 | 0.05 | +0.05 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 38,983 | +38,983 | 0.00 | 0.02 | +0.02 | buy |
| SG Americas Securities, LLC | 29,341 | 38,482 | +9,141 | 0.00 | 0.01 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 13,870 | 36,351 | +22,481 | 0.00 | 0.00 | +0.00 | buy |