| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARK Investment Management LLC | 11,313,623 | 9,460,939 | -1,852,684 | 4.19 | 3.35 | -0.84 | sell |
| BlackRock, Inc. | 7,680,073 | 8,348,977 | +668,904 | 0.01 | 0.01 | +0.00 | buy |
| Orbis Allan Gray Ltd | 6,106,011 | 5,449,161 | -656,850 | 1.23 | 1.02 | -0.20 | sell |
| Capital World Investors | 4,725,037 | 4,749,525 | +24,488 | 0.03 | 0.03 | -0.00 | buy |
| STATE STREET CORP | 3,982,500 | 4,321,666 | +339,166 | 0.01 | 0.01 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,377,164 | 2,509,915 | +132,751 | 0.01 | 0.01 | +0.00 | buy |
| T. Rowe Price Investment Management, Inc. | 2,952,595 | 2,053,017 | -899,578 | 0.10 | 0.07 | -0.02 | sell |
| SR ONE CAPITAL MANAGEMENT, LP | 2,038,763 | 2,038,763 | 0 | 10.59 | 10.70 | +0.11 | hold |
| TWO SIGMA INVESTMENTS, LP | 1,483,051 | 1,988,621 | +505,570 | 0.06 | 0.08 | +0.02 | buy |
| FMR LLC | 1,954,694 | 1,908,503 | -46,191 | 0.00 | 0.00 | -0.00 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 1,853,875 | 1,720,734 | -133,141 | 0.06 | 0.05 | -0.00 | sell |
| Nikko Asset Management Americas, Inc. | 1,853,875 | 1,720,097 | -133,778 | 1.25 | 1.21 | -0.04 | sell |
| EcoR1 Capital, LLC | 1,389,276 | 1,389,276 | 0 | 2.82 | 3.76 | +0.93 | hold |
| UBS Group AG | 1,762,530 | 1,317,499 | -445,031 | 0.01 | 0.01 | -0.00 | sell |
| Capital International Investors | 1,186,794 | 1,268,407 | +81,613 | 0.01 | 0.01 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 983,072 | 1,155,105 | +172,033 | 0.00 | 0.00 | +0.00 | buy |
| NEA Management Company, LLC | 1,058,570 | 1,058,570 | 0 | 2.86 | 3.64 | +0.77 | hold |
| Sixth Street Partners Management Company, L.P. | 0 | 1,057,837 | +1,057,837 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,039,349 | 1,057,837 | +18,488 | 0.01 | 0.01 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 893,812 | +893,812 | 0.00 | 0.03 | +0.03 | buy |
| MORGAN STANLEY | 668,142 | 879,949 | +211,807 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 802,181 | 863,091 | +60,910 | 0.01 | 0.01 | +0.00 | buy |
| CITADEL ADVISORS LLC | 516,352 | 465,796 | -50,556 | 0.02 | 0.01 | -0.00 | sell |
| JPMORGAN CHASE & CO | 457,639 | 431,669 | -25,970 | 0.00 | 0.00 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 593,406 | 427,178 | -166,228 | 0.04 | 0.02 | -0.02 | sell |
| MILLENNIUM MANAGEMENT LLC | 377,178 | 382,032 | +4,854 | 0.01 | 0.01 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 400,877 | 381,991 | -18,886 | 1.45 | 1.33 | -0.12 | sell |
| Bank of New York Mellon Corp | 311,383 | 326,761 | +15,378 | 0.00 | 0.00 | +0.00 | buy |
| Logos Global Management LP | 0 | 300,000 | +300,000 | 0.00 | 0.70 | +0.70 | buy |
| Squarepoint Ops LLC | 153,575 | 286,789 | +133,214 | 0.02 | 0.03 | +0.01 | buy |
| Jump Financial, LLC | 107,439 | 277,952 | +170,513 | 0.08 | 0.14 | +0.06 | buy |
| DIMENSIONAL FUND ADVISORS LP | 494,218 | 275,375 | -218,843 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 414,220 | 272,372 | -141,848 | 0.00 | 0.00 | -0.00 | sell |
| NORGES BANK | 0 | 270,756 | +270,756 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 280,709 | 263,169 | -17,540 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 286,839 | 250,614 | -36,225 | 0.00 | 0.00 | -0.00 | sell |
| Vestmark Advisory Solutions, Inc. | 256,779 | 242,266 | -14,513 | 0.14 | 0.12 | -0.01 | sell |
| RAYMOND JAMES FINANCIAL INC | 220,274 | 231,988 | +11,714 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 190,766 | 203,089 | +12,323 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 163,720 | 173,045 | +9,325 | 0.00 | 0.00 | +0.00 | buy |
| Marex Group plc | 134,097 | 170,584 | +36,487 | 0.07 | 0.07 | +0.00 | buy |
| Swiss National Bank | 169,700 | 169,200 | -500 | 0.00 | 0.00 | +0.00 | sell |
| Susquehanna Portfolio Strategies, LLC | 105,373 | 164,026 | +58,653 | 0.07 | 0.14 | +0.07 | buy |
| Legal & General Group Plc | 75,640 | 163,810 | +88,170 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 152,042 | 153,581 | +1,539 | 0.00 | 0.00 | -0.00 | buy |
| Versant Venture Management, LLC | 148,831 | 148,831 | 0 | 5.01 | 4.99 | -0.01 | hold |
| TD ASSET MANAGEMENT INC | 158,416 | 142,602 | -15,814 | 0.01 | 0.01 | +0.00 | sell |
| Pictet Asset Management Holding SA | 154,007 | 142,213 | -11,794 | 0.01 | 0.01 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 120,488 | 139,462 | +18,974 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 70,532 | 134,664 | +64,132 | 0.01 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 105,000 | 128,583 | +23,583 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 94,716 | 122,658 | +27,942 | 0.01 | 0.01 | +0.00 | buy |
| RHUMBLINE ADVISERS | 114,822 | 121,511 | +6,689 | 0.00 | 0.00 | +0.00 | buy |
| KBC Group NV | 116,847 | 116,847 | 0 | 0.01 | 0.01 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 96,357 | 114,337 | +17,980 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 21,970 | 114,316 | +92,346 | 0.00 | 0.00 | +0.00 | buy |
| Private Advisor Group, LLC | 106,662 | 111,129 | +4,467 | 0.02 | 0.03 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 89,683 | 110,689 | +21,006 | 0.13 | 0.20 | +0.07 | buy |
| CONGRESS ASSET MANAGEMENT CO | 108,371 | 109,453 | +1,082 | 0.04 | 0.04 | -0.00 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 107,529 | +107,529 | 0.00 | 0.31 | +0.31 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 116,107 | 102,669 | -13,438 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 83,356 | 101,854 | +18,498 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 73,325 | 101,649 | +28,324 | 0.01 | 0.01 | +0.00 | buy |
| Capital International Sarl | 102,278 | 101,238 | -1,040 | 0.08 | 0.08 | -0.00 | sell |
| Affinity Asset Advisors, LLC | 150,000 | 100,000 | -50,000 | 0.42 | 0.27 | -0.15 | sell |
| CLOUGH CAPITAL PARTNERS L P | 24,685 | 98,337 | +73,652 | 0.11 | 0.44 | +0.32 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 101,232 | 98,168 | -3,064 | 0.01 | 0.00 | -0.00 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 86,029 | 94,838 | +8,809 | 0.01 | 0.01 | +0.00 | buy |
| Slow Capital, Inc. | 91,223 | 92,894 | +1,671 | 0.56 | 0.59 | +0.03 | buy |
| Concurrent Investment Advisors, LLC | 62,423 | 90,537 | +28,114 | 0.03 | 0.04 | +0.01 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 95,770 | 89,242 | -6,528 | 0.04 | 0.03 | -0.01 | sell |
| GROUP ONE TRADING LLC | 96,001 | 85,040 | -10,961 | 0.15 | 0.13 | -0.02 | sell |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | 92,481 | 83,897 | -8,584 | 0.34 | 0.28 | -0.06 | sell |
| STATE OF MICHIGAN RETIREMENT SYSTEM | 0 | 82,547 | +82,547 | 0.00 | 0.02 | +0.02 | buy |
| OSAIC HOLDINGS, INC. | 60,056 | 79,501 | +19,445 | 0.00 | 0.01 | +0.00 | buy |
| Fisher Asset Management, LLC | 0 | 77,960 | +77,960 | 0.00 | 0.00 | +0.00 | buy |
| Trexquant Investment LP | 127,181 | 77,471 | -49,710 | 0.04 | 0.03 | -0.02 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 78,488 | 76,900 | -1,588 | 0.01 | 0.01 | +0.00 | sell |
| JONES FINANCIAL COMPANIES LLLP | 63,666 | 73,847 | +10,181 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 90,061 | 73,194 | -16,867 | 0.01 | 0.01 | -0.00 | sell |
| Russell Investments Group, Ltd. | 47,448 | 73,044 | +25,596 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 82,206 | 70,081 | -12,125 | 0.00 | 0.00 | -0.00 | sell |
| ALGERT GLOBAL LLC | 96,820 | 65,880 | -30,940 | 0.07 | 0.04 | -0.03 | sell |
| Invesco Ltd. | 64,117 | 64,989 | +872 | 0.00 | 0.00 | -0.00 | buy |
| Curi Capital, LLC | 49,706 | 59,032 | +9,326 | 0.04 | 0.05 | +0.01 | buy |
| CAPITAL INTERNATIONAL LTD /CA/ | 56,066 | 56,066 | 0 | 0.10 | 0.10 | +0.00 | hold |
| NOMURA HOLDINGS INC | 5,273 | 56,027 | +50,754 | 0.00 | 0.01 | +0.01 | buy |
| Rafferty Asset Management, LLC | 90,336 | 55,833 | -34,503 | 0.02 | 0.01 | -0.01 | sell |
| Green Alpha Advisors, LLC | 57,022 | 55,804 | -1,218 | 2.67 | 2.04 | -0.63 | sell |
| BENJAMIN EDWARDS INC | 55,506 | 54,488 | -1,018 | 0.03 | 0.03 | +0.00 | sell |
| MetLife Investment Management, LLC | 49,636 | 54,243 | +4,607 | 0.01 | 0.01 | +0.00 | buy |
| Quantinno Capital Management LP | 47,989 | 52,610 | +4,621 | 0.00 | 0.00 | -0.00 | buy |
| Cetera Investment Advisers | 59,245 | 52,368 | -6,877 | 0.00 | 0.00 | -0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 52,546 | 51,128 | -1,418 | 0.01 | 0.01 | -0.00 | sell |
| Cambridge Investment Research Advisors, Inc. | 37,992 | 46,210 | +8,218 | 0.00 | 0.01 | +0.00 | buy |
| Privium Fund Management B.V. | 42,874 | 44,974 | +2,100 | 0.42 | 0.45 | +0.03 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 16,400 | 43,900 | +27,500 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 43,411 | 42,512 | -899 | 0.01 | 0.01 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 47,065 | 42,389 | -4,676 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 32,254 | 40,879 | +8,625 | 0.00 | 0.00 | +0.00 | buy |