| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARK Investment Management LLC | 10,182,590 | 9,786,973 | -395,617 | 3.63 | 3.78 | +0.14 | sell |
| BlackRock, Inc. | 6,066,358 | 7,050,145 | +983,787 | 0.01 | 0.01 | +0.00 | buy |
| Capital International Investors | 5,593,747 | 5,649,258 | +55,511 | 0.05 | 0.06 | +0.01 | buy |
| Orbis Allan Gray Ltd | 2,764,532 | 4,982,085 | +2,217,553 | 0.65 | 1.39 | +0.73 | buy |
| STATE STREET CORP | 3,270,596 | 4,007,233 | +736,637 | 0.01 | 0.01 | +0.00 | buy |
| T. Rowe Price Investment Management, Inc. | 3,683,026 | 3,282,584 | -400,442 | 0.11 | 0.13 | +0.02 | sell |
| VANGUARD GROUP INC | 2,298,089 | 2,364,645 | +66,556 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 2,843,577 | 2,339,056 | -504,521 | 0.03 | 0.03 | +0.00 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 2,414,838 | 2,163,675 | -251,163 | 0.07 | 0.08 | +0.01 | sell |
| Nikko Asset Management Americas, Inc. | 2,414,271 | 2,163,675 | -250,596 | 1.17 | 1.36 | +0.19 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 2,071,883 | 2,141,170 | +69,287 | 0.01 | 0.01 | +0.00 | buy |
| SR ONE CAPITAL MANAGEMENT, LP | 1,048,951 | 2,038,763 | +989,812 | 11.06 | 19.11 | +8.05 | buy |
| FMR LLC | 1,929,154 | 1,885,663 | -43,491 | 0.01 | 0.01 | +0.00 | sell |
| MORGAN STANLEY | 511,380 | 1,397,859 | +886,479 | 0.00 | 0.01 | +0.00 | buy |
| EcoR1 Capital, LLC | 1,389,276 | 1,389,276 | 0 | 4.00 | 4.32 | +0.32 | hold |
| BANK OF AMERICA CORP /DE/ | 1,448,415 | 1,124,119 | -324,296 | 0.01 | 0.01 | -0.00 | sell |
| NEA Management Company, LLC | 1,587,854 | 1,058,570 | -529,284 | 5.81 | 3.76 | -2.05 | sell |
| TWO SIGMA INVESTMENTS, LP | 1,545,966 | 1,044,689 | -501,277 | 0.14 | 0.10 | -0.03 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 933,204 | 985,770 | +52,566 | 0.01 | 0.01 | +0.00 | buy |
| LOOMIS SAYLES & CO L P | 856,887 | 909,714 | +52,827 | 0.05 | 0.07 | +0.02 | buy |
| DIMENSIONAL FUND ADVISORS LP | 917,712 | 877,029 | -40,683 | 0.01 | 0.01 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 769,945 | 814,324 | +44,379 | 0.06 | 0.08 | +0.02 | buy |
| NORTHERN TRUST CORP | 761,115 | 779,930 | +18,815 | 0.01 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 321,094 | 593,416 | +272,322 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 1,344,700 | 572,972 | -771,728 | 0.13 | 0.07 | -0.06 | sell |
| ROYAL BANK OF CANADA | 337,138 | 466,170 | +129,032 | 0.00 | 0.01 | +0.00 | buy |
| BARCLAYS PLC | 380,623 | 349,851 | -30,772 | 0.01 | 0.01 | +0.00 | sell |
| AMERIPRISE FINANCIAL INC | 262,089 | 311,863 | +49,774 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 301,959 | 304,607 | +2,648 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 235,740 | 303,178 | +67,438 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 195,602 | 283,111 | +87,509 | 0.85 | 1.24 | +0.40 | buy |
| Contrarius Group Holdings Ltd | 374,954 | 270,350 | -104,604 | 1.03 | 0.79 | -0.24 | sell |
| Vestmark Advisory Solutions, Inc. | 484,975 | 238,962 | -246,013 | 0.34 | 0.30 | -0.05 | sell |
| GOLDMAN SACHS GROUP INC | 220,600 | 233,542 | +12,942 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 194,579 | 211,061 | +16,482 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 235,920 | 192,593 | -43,327 | 0.01 | 0.01 | +0.00 | sell |
| BANK OF MONTREAL /CAN/ | 493,743 | 187,219 | -306,524 | 0.01 | 0.00 | -0.01 | sell |
| Nuveen, LLC | 184,853 | 182,841 | -2,012 | 0.00 | 0.00 | +0.00 | sell |
| TD ASSET MANAGEMENT INC | 228,416 | 174,616 | -53,800 | 0.01 | 0.01 | -0.00 | sell |
| O'Neil Global Advisors, Inc. | 0 | 168,715 | +168,715 | 0.00 | 2.01 | +2.01 | buy |
| CITADEL ADVISORS LLC | 18,878 | 167,101 | +148,223 | 0.00 | 0.01 | +0.01 | buy |
| Swiss National Bank | 156,400 | 159,100 | +2,700 | 0.00 | 0.01 | +0.00 | buy |
| Rafferty Asset Management, LLC | 114,348 | 154,295 | +39,947 | 0.02 | 0.03 | +0.01 | buy |
| Versant Venture Management, LLC | 498,558 | 148,831 | -349,727 | 29.52 | 4.54 | -24.98 | sell |
| Rockefeller Capital Management L.P. | 115,356 | 148,531 | +33,175 | 0.01 | 0.02 | +0.01 | buy |
| Woodline Partners LP | 149,267 | 143,575 | -5,692 | 0.04 | 0.04 | +0.01 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 127,500 | 131,300 | +3,800 | 0.01 | 0.01 | +0.00 | buy |
| RHUMBLINE ADVISERS | 123,893 | 123,907 | +14 | 0.01 | 0.01 | +0.00 | buy |
| Marex Group plc | 19,483 | 123,769 | +104,286 | 0.02 | 0.10 | +0.08 | buy |
| Private Advisor Group, LLC | 111,949 | 118,113 | +6,164 | 0.03 | 0.04 | +0.01 | buy |
| Reynders McVeigh Capital Management, LLC | 111,431 | 113,000 | +1,569 | 0.27 | 0.34 | +0.07 | buy |
| RAYMOND JAMES FINANCIAL INC | 97,573 | 109,830 | +12,257 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 103,628 | 109,372 | +5,744 | 0.00 | 0.00 | +0.00 | buy |
| NWAM LLC | 18,315 | 101,769 | +83,454 | 0.06 | 0.41 | +0.35 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 100,000 | +100,000 | 0.00 | 0.25 | +0.25 | buy |
| Capital International Sarl | 91,517 | 99,657 | +8,140 | 0.09 | 0.11 | +0.03 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 105,398 | 99,204 | -6,194 | 0.01 | 0.01 | +0.00 | sell |
| EverSource Wealth Advisors, LLC | 92,943 | 97,434 | +4,491 | 0.20 | 0.25 | +0.05 | buy |
| GROUP ONE TRADING LLC | 5,712 | 97,242 | +91,530 | 0.01 | 0.19 | +0.18 | buy |
| Baker Chad R | 93,205 | 93,205 | 0 | 0.84 | 1.04 | +0.20 | hold |
| Legal & General Group Plc | 129,567 | 92,479 | -37,088 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 86,620 | 86,334 | -286 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 70,093 | 86,282 | +16,189 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 82,607 | 84,016 | +1,409 | 0.01 | 0.01 | +0.00 | buy |
| VAN ECK ASSOCIATES CORP | 83,010 | 83,644 | +634 | 0.00 | 0.01 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 66,367 | 76,535 | +10,168 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 74,907 | 74,911 | +4 | 0.00 | 0.00 | +0.00 | buy |
| Slow Capital, Inc. | 75,396 | 73,287 | -2,109 | 0.45 | 0.56 | +0.11 | sell |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | 83,120 | 72,339 | -10,781 | 0.32 | 0.29 | -0.03 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 67,942 | 70,389 | +2,447 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 62,574 | 69,097 | +6,523 | 0.00 | 0.01 | +0.00 | buy |
| CONGRESS ASSET MANAGEMENT CO | 68,404 | 68,110 | -294 | 0.02 | 0.03 | +0.01 | sell |
| Invesco Ltd. | 66,648 | 65,327 | -1,321 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 22,469 | 64,946 | +42,477 | 0.03 | 0.12 | +0.09 | buy |
| DEUTSCHE BANK AG\ | 57,260 | 64,802 | +7,542 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 48,015 | 63,830 | +15,815 | 0.00 | 0.00 | +0.00 | buy |
| Del-Sette Capital Management, LLC | 63,843 | 62,494 | -1,349 | 2.16 | 2.52 | +0.36 | sell |
| CAPITAL INTERNATIONAL LTD /CA/ | 61,552 | 61,552 | 0 | 0.11 | 0.14 | +0.03 | hold |
| CITIGROUP INC | 126,892 | 60,489 | -66,403 | 0.00 | 0.00 | -0.00 | sell |
| LAZARD ASSET MANAGEMENT LLC | 59,333 | 58,326 | -1,007 | 0.00 | 0.01 | +0.00 | sell |
| GUGGENHEIM CAPITAL LLC | 58,488 | 57,461 | -1,027 | 0.02 | 0.03 | +0.00 | sell |
| OSAIC HOLDINGS, INC. | 52,035 | 55,935 | +3,900 | 0.00 | 0.00 | -0.00 | buy |
| Green Alpha Advisors, LLC | 58,463 | 55,012 | -3,451 | 2.72 | 3.44 | +0.73 | sell |
| BENJAMIN EDWARDS INC | 57,760 | 54,220 | -3,540 | 0.04 | 0.04 | +0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 51,565 | 51,667 | +102 | 0.01 | 0.01 | +0.00 | buy |
| Curi Capital, LLC | 51,417 | 51,483 | +66 | 0.05 | 0.06 | +0.01 | buy |
| PATHWAY CAPITAL MANAGEMENT, LP | 0 | 50,049 | +50,049 | 0.00 | 15.95 | +15.95 | buy |
| MetLife Investment Management, LLC | 49,339 | 48,235 | -1,104 | 0.01 | 0.02 | +0.00 | sell |
| Cambridge Investment Research Advisors, Inc. | 45,467 | 46,587 | +1,120 | 0.01 | 0.01 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 29,767 | 44,715 | +14,948 | 0.00 | 0.00 | +0.00 | buy |
| Koss-Olinger Consulting, LLC | 42,197 | 42,197 | 0 | 0.17 | 0.17 | +0.00 | hold |
| Russell Investments Group, Ltd. | 0 | 42,033 | +42,033 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 39,313 | 42,010 | +2,697 | 0.00 | 0.00 | +0.00 | buy |
| Palo Alto Investors LP | 44,625 | 41,226 | -3,399 | 0.46 | 0.49 | +0.03 | sell |
| DekaBank Deutsche Girozentrale | 40,745 | 40,745 | 0 | 0.00 | 0.00 | +0.00 | hold |
| State of New Jersey Common Pension Fund D | 50,185 | 40,270 | -9,915 | 0.01 | 0.01 | +0.00 | sell |
| Privium Fund Management B.V. | 44,700 | 40,000 | -4,700 | 0.47 | 0.47 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 42,950 | 38,550 | -4,400 | 0.00 | 0.00 | +0.00 | sell |
| Susquehanna Portfolio Strategies, LLC | 31,015 | 37,494 | +6,479 | 0.03 | 0.04 | +0.01 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 36,486 | +36,486 | 0.00 | 0.00 | +0.00 | buy |