| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| EVENTIDE ASSET MANAGEMENT, LLC | 5,945,488 | 6,253,673 | +308,185 | 0.99 | 1.31 | +0.33 | buy |
| Bruce & Co., Inc. | 550,700 | 665,700 | +115,000 | 1.58 | 2.82 | +1.25 | buy |
| Granahan Investment Management, LLC | 248,449 | 299,632 | +51,183 | 0.12 | 0.17 | +0.05 | buy |
| PURA VIDA INVESTMENTS, LLC | 281,250 | 281,164 | -86 | 18.94 | 26.68 | +7.74 | sell |
| PERCEPTIVE ADVISORS LLC | 842,944 | 832,944 | -10,000 | 0.17 | 0.20 | +0.03 | sell |
| Eversept Partners, LP | 1,414,838 | 1,249,441 | -165,397 | 0.75 | 1.02 | +0.27 | sell |
| RTW INVESTMENTS, LP | 2,000,000 | 1,500,000 | -500,000 | 0.20 | 0.20 | +0.00 | sell |