| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| EVENTIDE ASSET MANAGEMENT, LLC | 0 | 4,928,019 | +4,928,019 | 0.00 | 1.20 | +1.20 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 3,901,599 | +3,901,599 | 0.00 | 0.01 | +0.01 | buy |
| Soleus Capital Management, L.P. | 0 | 3,395,341 | +3,395,341 | 0.00 | 3.26 | +3.26 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 0 | 3,332,220 | +3,332,220 | 0.00 | 0.22 | +0.22 | buy |
| RTW INVESTMENTS, LP | 0 | 3,299,870 | +3,299,870 | 0.00 | 0.62 | +0.62 | buy |
| Sands Capital Alternatives, LLC | 0 | 3,103,782 | +3,103,782 | 0.00 | 9.29 | +9.29 | buy |
| Omega Fund Management, LLC | 0 | 1,988,287 | +1,988,287 | 0.00 | 14.36 | +14.36 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 1,593,608 | +1,593,608 | 0.00 | 0.69 | +0.69 | buy |
| BlackRock, Inc. | 0 | 1,427,150 | +1,427,150 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 0 | 1,401,653 | +1,401,653 | 0.00 | 0.00 | +0.00 | buy |
| Holocene Advisors, LP | 0 | 1,107,812 | +1,107,812 | 0.00 | 0.04 | +0.04 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 1,097,263 | +1,097,263 | 0.00 | 0.00 | +0.00 | buy |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 0 | 1,016,000 | +1,016,000 | 0.00 | 0.25 | +0.25 | buy |
| CITADEL ADVISORS LLC | 0 | 946,350 | +946,350 | 0.00 | 0.01 | +0.01 | buy |
| ArrowMark Colorado Holdings LLC | 0 | 932,128 | +932,128 | 0.00 | 0.16 | +0.16 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 882,277 | +882,277 | 0.00 | 0.10 | +0.10 | buy |
| VANGUARD GROUP INC | 0 | 709,255 | +709,255 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 673,658 | +673,658 | 0.00 | 0.01 | +0.01 | buy |
| JANUS HENDERSON GROUP PLC | 0 | 665,653 | +665,653 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 636,204 | +636,204 | 0.00 | 0.00 | +0.00 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 0 | 500,000 | +500,000 | 0.00 | 0.10 | +0.10 | buy |
| PURA VIDA INVESTMENTS, LLC | 0 | 429,120 | +429,120 | 0.00 | 38.36 | +38.36 | buy |
| Clearbridge Investments, LLC | 0 | 369,225 | +369,225 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 364,329 | +364,329 | 0.00 | 0.01 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 306,017 | +306,017 | 0.00 | 0.00 | +0.00 | buy |
| LORD, ABBETT & CO. LLC | 0 | 228,160 | +228,160 | 0.00 | 0.01 | +0.01 | buy |
| Jain Global LLC | 0 | 148,512 | +148,512 | 0.00 | 0.04 | +0.04 | buy |
| Walleye Capital LLC | 0 | 148,105 | +148,105 | 0.00 | 0.02 | +0.02 | buy |
| BRAIDWELL LP | 0 | 140,000 | +140,000 | 0.00 | 0.06 | +0.06 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 137,322 | +137,322 | 0.00 | 0.01 | +0.01 | buy |
| Woodline Partners LP | 0 | 125,000 | +125,000 | 0.00 | 0.01 | +0.01 | buy |
| UBS Group AG | 0 | 124,340 | +124,340 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 0 | 111,487 | +111,487 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 105,972 | +105,972 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0 | 101,614 | +101,614 | 0.00 | 0.00 | +0.00 | buy |
| Alyeska Investment Group, L.P. | 0 | 75,000 | +75,000 | 0.00 | 0.00 | +0.00 | buy |
| JENNISON ASSOCIATES LLC | 0 | 67,611 | +67,611 | 0.00 | 0.00 | +0.00 | buy |
| Bellevue Group AG | 0 | 66,825 | +66,825 | 0.00 | 0.02 | +0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 61,558 | +61,558 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 58,422 | +58,422 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 57,158 | +57,158 | 0.00 | 0.07 | +0.07 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 54,025 | +54,025 | 0.00 | 0.00 | +0.00 | buy |
| Ghisallo Capital Management LLC | 0 | 50,000 | +50,000 | 0.00 | 0.05 | +0.05 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 49,878 | +49,878 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 0 | 39,876 | +39,876 | 0.00 | 0.00 | +0.00 | buy |
| Evanson Asset Management, LLC | 0 | 38,772 | +38,772 | 0.00 | 0.03 | +0.03 | buy |
| Values First Advisors, Inc. | 0 | 37,585 | +37,585 | 0.00 | 0.27 | +0.27 | buy |
| DAVIDSON KEMPNER CAPITAL MANAGEMENT LP | 0 | 31,000 | +31,000 | 0.00 | 0.01 | +0.01 | buy |
| Verition Fund Management LLC | 0 | 27,217 | +27,217 | 0.00 | 0.00 | +0.00 | buy |
| SOROS FUND MANAGEMENT LLC | 0 | 25,968 | +25,968 | 0.00 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 0 | 25,793 | +25,793 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 21,353 | +21,353 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 20,751 | +20,751 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 0 | 20,131 | +20,131 | 0.00 | 0.01 | +0.01 | buy |
| BARCLAYS PLC | 0 | 17,425 | +17,425 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 0 | 16,464 | +16,464 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 15,820 | +15,820 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 0 | 12,880 | +12,880 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 12,500 | +12,500 | 0.00 | 0.07 | +0.07 | buy |
| DEUTSCHE BANK AG\ | 0 | 12,079 | +12,079 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 11,976 | +11,976 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 0 | 11,817 | +11,817 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 9,339 | +9,339 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 8,370 | +8,370 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0 | 7,772 | +7,772 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 0 | 6,883 | +6,883 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 0 | 6,485 | +6,485 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 6,260 | +6,260 | 0.00 | 0.00 | +0.00 | buy |
| Sandia Investment Management LP | 0 | 6,000 | +6,000 | 0.00 | 0.21 | +0.21 | buy |
| Police & Firemen's Retirement System of New Jersey | 0 | 2,751 | +2,751 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 0 | 2,400 | +2,400 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 1,700 | +1,700 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 1,339 | +1,339 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 1,337 | +1,337 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 1,115 | +1,115 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 1,097 | +1,097 | 0.00 | 0.00 | +0.00 | buy |
| Zimmer Partners, LP | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| GPS Wealth Strategies Group, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Stonebridge Financial Group, LLC | 0 | 911 | +911 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 830 | +830 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 720 | +720 | 0.00 | 0.00 | +0.00 | buy |
| PSI Advisors, LLC | 0 | 682 | +682 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 667 | +667 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 644 | +644 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 625 | +625 | 0.00 | 0.00 | +0.00 | buy |
| CoreCap Advisors, LLC | 0 | 560 | +560 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 0 | 456 | +456 | 0.00 | 0.00 | +0.00 | buy |
| Banque Transatlantique SA | 0 | 365 | +365 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 237 | +237 | 0.00 | 0.00 | +0.00 | buy |
| PRIVATE TRUST CO NA | 0 | 150 | +150 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 0 | 90 | +90 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 0 | 85 | +85 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 0 | 74 | +74 | 0.00 | 0.00 | +0.00 | buy |
| WPG Advisers, LLC | 0 | 28 | +28 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 15 | +15 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |