| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Boxer Capital Management, LLC | 1,708,187 | 2,108,014 | +399,827 | 0.19 | 0.49 | +0.30 | buy |
| Marex Group plc | 0 | 56,270 | +56,270 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 485,381 | 529,327 | +43,946 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 83,387 | 116,907 | +33,520 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 18,814 | 41,846 | +23,032 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 634,500 | 656,700 | +22,200 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 12,493 | 33,823 | +21,330 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 17,251 | +17,251 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 8,502 | 20,238 | +11,736 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 148,326 | 155,215 | +6,889 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 10,376 | 13,586 | +3,210 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 402,336 | 404,955 | +2,619 | 0.00 | 0.00 | -0.00 | buy |
| Cerity Partners LLC | 32,877 | 34,565 | +1,688 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 1,899 | 3,346 | +1,447 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 7,575 | 7,887 | +312 | 0.00 | 0.00 | -0.00 | buy |
| Sterling Capital Management LLC | 42 | 227 | +185 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 10,909,256 | 10,909,256 | 0 | 0.29 | 0.20 | -0.09 | hold |
| Ameritas Investment Partners, Inc. | 819 | 819 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD ASSET MANAGEMENT INC | 160,652 | 160,652 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 955 | 955 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 10,123,824 | 10,123,824 | 0 | 0.14 | 0.09 | -0.05 | hold |
| Bank of New York Mellon Corp | 28,613 | 28,613 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Militia Capital Partners, LP | 4,300 | 4,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 2,741 | 2,741 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 962 | 962 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 3,622 | 3,622 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 334 | 334 | 0 | 0.00 | 0.00 | 0.00 | hold |
| GROUP ONE TRADING LLC | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HSBC HOLDINGS PLC | 20,640 | 20,630 | -10 | 0.00 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 50 | 0 | -50 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 6,554 | 6,458 | -96 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 508 | 400 | -108 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 70,045 | 69,252 | -793 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 20,572 | 19,668 | -904 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 10,215 | 9,300 | -915 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,010,392 | 1,009,204 | -1,188 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 117,200 | 114,050 | -3,150 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 29,773 | 23,145 | -6,628 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 293,396 | 286,046 | -7,350 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 10,981 | 0 | -10,981 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 11,925 | 0 | -11,925 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 38,339 | 24,700 | -13,639 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 1,069,773 | 1,047,725 | -22,048 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 111,000 | 88,500 | -22,500 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 300,000 | 260,400 | -39,600 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 123,899 | 80,723 | -43,176 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 231,839 | 183,667 | -48,172 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,029,199 | 976,147 | -53,052 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 61,149 | 0 | -61,149 | 0.00 | 0.00 | -0.00 | sell |
| EXCHANGE TRADED CONCEPTS, LLC | 64,409 | 0 | -64,409 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 166,830 | 15,499 | -151,331 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 462,555 | 146,770 | -315,785 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 392,155 | 0 | -392,155 | 0.00 | 0.00 | -0.00 | sell |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 494,497 | 0 | -494,497 | 0.00 | 0.00 | -0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 666,574 | 0 | -666,574 | 0.00 | 0.00 | -0.00 | sell |