| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| SUVRETTA CAPITAL MANAGEMENT, LLC | 3,338,466 | 5,067,394 | +1,728,928 | 0.58 | 0.59 | +0.01 | buy |
| Exome Asset Management LLC | 283,599 | 689,137 | +405,538 | 1.00 | 1.78 | +0.77 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 401,100 | +401,100 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 35,707 | 344,561 | +308,854 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 196,248 | 490,532 | +294,284 | 0.19 | 0.27 | +0.08 | buy |
| Catalio Capital Management, LP | 0 | 202,139 | +202,139 | 0.00 | 0.14 | +0.14 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 147,654 | +147,654 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 79,120 | 209,893 | +130,773 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 117,816 | +117,816 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 86,085 | 192,207 | +106,122 | 0.03 | 0.06 | +0.02 | buy |
| Cubist Systematic Strategies, LLC | 0 | 57,070 | +57,070 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 29,976 | 85,767 | +55,791 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 49,878 | +49,878 | 0.00 | 0.01 | +0.01 | buy |
| Nantahala Capital Management, LLC | 4,779,708 | 4,822,693 | +42,985 | 1.57 | 1.15 | -0.42 | buy |
| CITADEL ADVISORS LLC | 333,323 | 374,256 | +40,933 | 0.00 | 0.00 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 32,086 | +32,086 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 144,942 | 166,243 | +21,301 | 0.02 | 0.02 | -0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 52,368 | 70,168 | +17,800 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 30,499 | 45,689 | +15,190 | 0.00 | 0.00 | -0.00 | buy |
| Virtu Financial LLC | 0 | 13,564 | +13,564 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 12,519 | +12,519 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 11,949 | +11,949 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 10,550 | +10,550 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 10,266 | +10,266 | 0.00 | 0.00 | +0.00 | buy |
| SHERBROOKE PARK ADVISERS LLC | 45,157 | 55,342 | +10,185 | 0.07 | 0.07 | +0.01 | buy |
| Brooklyn Investment Group | 3,936 | 12,190 | +8,254 | 0.01 | 0.01 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 8,014 | 15,586 | +7,572 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 1,245,319 | 1,252,440 | +7,121 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 3,975 | 8,332 | +4,357 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 120,611 | 123,711 | +3,100 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 1,667 | 4,015 | +2,348 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 0 | 2,100 | +2,100 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 34,117 | 36,147 | +2,030 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 2,021 | +2,021 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 141,873 | 143,588 | +1,715 | 0.00 | 0.00 | -0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 460 | 1,960 | +1,500 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 145 | 1,507 | +1,362 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 703 | +703 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 2,294 | 2,812 | +518 | 0.00 | 0.00 | -0.00 | buy |
| Simplify Asset Management Inc. | 80,714 | 81,134 | +420 | 0.03 | 0.01 | -0.02 | buy |
| RHUMBLINE ADVISERS | 88,607 | 88,993 | +386 | 0.00 | 0.00 | -0.00 | buy |
| Rialto Wealth Management, LLC | 0 | 159 | +159 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 105 | +105 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 22,675 | 22,725 | +50 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| BESSEMER GROUP INC | 286,988 | 286,988 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 6,079 | 6,079 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4,496 | 4,496 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ZACKS INVESTMENT MANAGEMENT | 20,999 | 20,999 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 65,590 | 65,590 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RBF Capital, LLC | 80,506 | 80,506 | 0 | 0.02 | 0.01 | -0.01 | hold |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,000,000 | 3,000,000 | 0 | 0.02 | 0.02 | -0.01 | hold |
| COUNTRY TRUST BANK | 30,186 | 30,186 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 10,229,099 | 10,229,099 | 0 | 0.64 | 0.49 | -0.15 | hold |
| J. Goldman & Co LP | 20,250 | 20,250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DekaBank Deutsche Girozentrale | 60,000 | 60,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 59,533 | 59,533 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Alphabet Inc. | 14,262 | 14,262 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Steward Partners Investment Advisory, LLC | 790 | 790 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PrairieView Partners, LLC | 5,000 | 5,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ikarian Capital, LLC | 200,096 | 200,096 | 0 | 0.27 | 0.19 | -0.08 | hold |
| TCG Crossover Management, LLC | 5,250,000 | 5,250,000 | 0 | 2.41 | 2.06 | -0.35 | hold |
| SBI Securities Co., Ltd. | 26 | 26 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 12,475 | 12,475 | 0 | 0.00 | 0.00 | -0.00 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 83,428 | 83,428 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FIDUCIARY TRUST CO | 136,555 | 136,555 | 0 | 0.01 | 0.01 | -0.00 | hold |
| FRANKLIN RESOURCES INC | 24,821 | 24,821 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 13,100 | 13,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 91,200 | 91,200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 2,147 | 2,147 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 3 | 0 | -3 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 10 | 0 | -10 | 0.00 | 0.00 | 0.00 | sell |
| Larson Financial Group LLC | 15 | 0 | -15 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 314 | 216 | -98 | 0.00 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| C M BIDWELL & ASSOCIATES LTD | 117 | 0 | -117 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 1,239 | 561 | -678 | 0.00 | 0.00 | -0.00 | sell |
| Belvedere Trading LLC | 758 | 0 | -758 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 75,959 | 74,961 | -998 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 23,470 | 22,411 | -1,059 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 6,520 | 5,288 | -1,232 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 19,888 | 18,548 | -1,340 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 67,043 | 65,388 | -1,655 | 0.00 | 0.00 | -0.00 | sell |
| Jain Global LLC | 15,409 | 13,051 | -2,358 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 583,203 | 580,661 | -2,542 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 34,264 | 30,520 | -3,744 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 35,601 | 31,592 | -4,009 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 30,850 | 26,381 | -4,469 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 30,442 | 25,375 | -5,067 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 285,491 | 279,812 | -5,679 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 17,475 | 11,657 | -5,818 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 10,455 | 3,026 | -7,429 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 1,418,690 | 1,407,049 | -11,641 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 49,722 | 37,829 | -11,893 | 0.00 | 0.00 | -0.00 | sell |
| WINTON GROUP Ltd | 12,997 | 0 | -12,997 | 0.00 | 0.00 | -0.00 | sell |
| Mariner, LLC | 16,516 | 0 | -16,516 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 68,069 | 50,490 | -17,579 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 169,542 | 150,274 | -19,268 | 0.00 | 0.00 | -0.00 | sell |
| CANTOR FITZGERALD, L. P. | 20,000 | 0 | -20,000 | 0.00 | 0.00 | -0.00 | sell |