| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAILLIE GIFFORD & CO | 44,655,817 | 43,449,041 | -1,206,776 | 3.70 | 4.02 | +0.32 | sell |
| VANGUARD GROUP INC | 39,036,872 | 39,562,796 | +525,924 | 0.08 | 0.09 | +0.01 | buy |
| FMR LLC | 13,599,837 | 21,161,285 | +7,561,448 | 0.10 | 0.16 | +0.06 | buy |
| STATE STREET CORP | 14,452,035 | 15,023,936 | +571,901 | 0.07 | 0.08 | +0.01 | buy |
| Theleme Partners LLP | 7,321,797 | 7,226,861 | -94,936 | 42.87 | 42.68 | -0.19 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 6,750,479 | 6,891,465 | +140,986 | 0.07 | 0.07 | +0.01 | buy |
| MORGAN STANLEY | 5,493,965 | 5,006,520 | -487,445 | 0.05 | 0.05 | -0.00 | sell |
| Flagship Pioneering Inc. | 9,666,038 | 4,632,149 | -5,033,889 | 67.56 | 65.22 | -2.34 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 5,604,703 | 4,318,571 | -1,286,132 | 0.11 | 0.09 | -0.01 | sell |
| GOLDMAN SACHS GROUP INC | 3,929,912 | 4,185,558 | +255,646 | 0.09 | 0.10 | +0.01 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 3,673,043 | 3,870,993 | +197,950 | 0.14 | 0.13 | -0.01 | buy |
| Capital World Investors | 3,648,117 | 3,667,171 | +19,054 | 0.06 | 0.07 | +0.01 | buy |
| NORGES BANK | 3,794,877 | 3,350,793 | -444,084 | 0.06 | 0.06 | -0.00 | sell |
| BANQUE PICTET & CIE SA | 3,161,729 | 3,154,429 | -7,300 | 3.54 | 3.84 | +0.30 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 3,478,412 | 2,894,995 | -583,417 | 0.34 | 0.32 | -0.02 | sell |
| NORTHERN TRUST CORP | 2,868,954 | 2,839,267 | -29,687 | 0.05 | 0.06 | +0.00 | sell |
| Invesco Ltd. | 2,769,922 | 2,540,271 | -229,651 | 0.06 | 0.06 | +0.00 | sell |
| Bank of New York Mellon Corp | 2,305,976 | 2,270,748 | -35,228 | 0.05 | 0.05 | +0.00 | sell |
| Legal & General Group Plc | 2,337,715 | 2,077,591 | -260,124 | 0.07 | 0.07 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,967,589 | 2,049,695 | +82,106 | 0.05 | 0.05 | -0.00 | buy |
| Mawer Investment Management Ltd. | 1,916,570 | 1,903,326 | -13,244 | 0.95 | 1.07 | +0.12 | sell |
| JPMORGAN CHASE & CO | 1,441,440 | 1,750,475 | +309,035 | 0.01 | 0.02 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,019,197 | 1,599,728 | +580,531 | 0.01 | 0.02 | +0.01 | buy |
| Bellevue Group AG | 1,711,089 | 1,563,735 | -147,354 | 2.78 | 3.02 | +0.24 | sell |
| Sumitomo Mitsui Trust Group, Inc. | 1,545,829 | 1,446,717 | -99,112 | 0.11 | 0.13 | +0.01 | sell |
| DIMENSIONAL FUND ADVISORS LP | 1,397,734 | 1,427,300 | +29,566 | 0.04 | 0.04 | +0.00 | buy |
| BARCLAYS PLC | 1,192,897 | 1,339,753 | +146,856 | 0.06 | 0.07 | +0.02 | buy |
| JANE STREET GROUP, LLC | 493,590 | 1,314,499 | +820,909 | 0.07 | 0.17 | +0.10 | buy |
| Pictet Asset Management Holding SA | 2,621,637 | 1,114,162 | -1,507,475 | 0.31 | 0.15 | -0.15 | sell |
| UBS Group AG | 1,017,188 | 1,081,761 | +64,573 | 0.04 | 0.04 | +0.00 | buy |
| ARK Investment Management LLC | 1,217,383 | 1,054,094 | -163,289 | 0.90 | 1.11 | +0.21 | sell |
| DEUTSCHE BANK AG\ | 972,202 | 1,044,391 | +72,189 | 0.05 | 0.06 | +0.01 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 1,129,939 | 1,003,122 | -126,817 | 0.08 | 0.09 | +0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 917,835 | 987,850 | +70,015 | 0.01 | 0.01 | +0.00 | buy |
| Swiss National Bank | 970,600 | 963,600 | -7,000 | 0.07 | 0.08 | +0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 746,892 | 738,116 | -8,776 | 0.10 | 0.09 | -0.00 | sell |
| National Pension Service | 751,739 | 738,076 | -13,663 | 0.10 | 0.10 | +0.00 | sell |
| Amundi | 647,589 | 735,429 | +87,840 | 0.03 | 0.03 | +0.00 | buy |
| Nikko Asset Management Americas, Inc. | 741,783 | 701,049 | -40,734 | 0.78 | 0.96 | +0.18 | sell |
| Mitsubishi UFJ Trust & Banking Corp | 763,976 | 675,927 | -88,049 | 0.19 | 0.19 | +0.00 | sell |
| ROYAL BANK OF CANADA | 662,017 | 640,546 | -21,471 | 0.02 | 0.02 | +0.00 | sell |
| RHUMBLINE ADVISERS | 588,892 | 585,992 | -2,900 | 0.06 | 0.07 | +0.01 | sell |
| Bank Pictet & Cie (Europe) AG | 523,626 | 522,626 | -1,000 | 1.46 | 1.52 | +0.06 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 521,204 | 520,535 | -669 | 0.07 | 0.08 | +0.01 | sell |
| FIRST TRUST ADVISORS LP | 604,346 | 508,832 | -95,514 | 0.07 | 0.06 | -0.00 | sell |
| Candriam S.C.A. | 442,045 | 482,052 | +40,007 | 0.30 | 0.35 | +0.05 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 446,473 | 477,941 | +31,468 | 0.07 | 0.07 | +0.00 | buy |
| HSBC HOLDINGS PLC | 530,137 | 463,443 | -66,694 | 0.04 | 0.04 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 488,110 | 461,985 | -26,125 | 0.02 | 0.02 | +0.01 | sell |
| CITADEL ADVISORS LLC | 272,337 | 460,456 | +188,119 | 0.03 | 0.05 | +0.03 | buy |
| CITIGROUP INC | 428,197 | 453,532 | +25,335 | 0.05 | 0.05 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 433,847 | 420,762 | -13,085 | 0.06 | 0.07 | +0.00 | sell |
| WELLS FARGO & COMPANY/MN | 273,500 | 416,480 | +142,980 | 0.01 | 0.01 | +0.01 | buy |
| ALLIANCEBERNSTEIN L.P. | 385,362 | 405,705 | +20,343 | 0.01 | 0.02 | +0.00 | buy |
| Douglas Lane & Associates, LLC | 393,039 | 404,200 | +11,161 | 0.59 | 0.68 | +0.09 | buy |
| ProShare Advisors LLC | 444,621 | 401,548 | -43,073 | 0.13 | 0.13 | +0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 363,905 | 364,233 | +328 | 0.02 | 0.03 | +0.00 | buy |
| Lingotto Investment Management LLP | 303,095 | 348,095 | +45,000 | 1.35 | 1.39 | +0.04 | buy |
| ROYAL LONDON ASSET MANAGEMENT LTD | 386,528 | 335,309 | -51,219 | 0.10 | 0.10 | -0.00 | sell |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 385,736 | 334,826 | -50,910 | 0.14 | 0.08 | -0.06 | sell |
| LETKO, BROSSEAU & ASSOCIATES INC | 320,050 | 315,400 | -4,650 | 0.59 | 0.71 | +0.12 | sell |
| Aberdeen Group plc | 463,114 | 292,662 | -170,452 | 0.10 | 0.07 | -0.03 | sell |
| AMERIPRISE FINANCIAL INC | 298,657 | 289,364 | -9,293 | 0.01 | 0.01 | +0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 299,510 | 284,337 | -15,173 | 0.03 | 0.03 | +0.00 | sell |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 301,837 | 283,933 | -17,904 | 0.07 | 0.07 | +0.00 | sell |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 272,081 | 283,909 | +11,828 | 0.26 | 0.30 | +0.04 | buy |
| STATE OF MICHIGAN RETIREMENT SYSTEM | 90,841 | 274,248 | +183,407 | 0.05 | 0.17 | +0.12 | buy |
| Korea Investment CORP | 264,476 | 273,498 | +9,022 | 0.07 | 0.08 | +0.01 | buy |
| Rafferty Asset Management, LLC | 243,162 | 261,760 | +18,598 | 0.10 | 0.12 | +0.02 | buy |
| Man Group plc | 23,062 | 255,735 | +232,673 | 0.01 | 0.08 | +0.07 | buy |
| Neuberger Berman Group LLC | 188,554 | 254,821 | +66,267 | 0.02 | 0.02 | +0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 252,453 | +252,453 | 0.00 | 0.06 | +0.06 | buy |
| Telemark Asset Management, LLC | 250,000 | 250,000 | 0 | 2.75 | 2.68 | -0.07 | hold |
| NATIXIS | 0 | 246,806 | +246,806 | 0.00 | 0.18 | +0.18 | buy |
| TWINBEECH CAPITAL LP | 0 | 246,518 | +246,518 | 0.00 | 0.58 | +0.58 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 244,981 | 245,687 | +706 | 0.13 | 0.14 | +0.01 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 236,438 | 233,946 | -2,492 | 0.03 | 0.03 | +0.00 | sell |
| APG Asset Management N.V. | 196,333 | 222,633 | +26,300 | 0.03 | 0.04 | +0.01 | buy |
| DekaBank Deutsche Girozentrale | 221,718 | 221,213 | -505 | 0.05 | 0.05 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 214,631 | 218,814 | +4,183 | 0.03 | 0.05 | +0.01 | buy |
| South Dakota Investment Council | 213,163 | 212,257 | -906 | 0.47 | 0.52 | +0.04 | sell |
| PRUDENTIAL FINANCIAL INC | 238,209 | 211,023 | -27,186 | 0.04 | 0.04 | +0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 248,419 | 210,682 | -37,737 | 0.03 | 0.02 | -0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 198,126 | 209,155 | +11,029 | 0.06 | 0.07 | +0.01 | buy |
| AXA S.A. | 203,042 | 204,989 | +1,947 | 0.06 | 0.07 | +0.01 | buy |
| Bank Julius Baer & Co. Ltd, Zurich | 233,824 | 199,692 | -34,132 | 0.10 | 0.10 | +0.00 | sell |
| CANADA LIFE ASSURANCE Co | 182,635 | 195,976 | +13,341 | 0.04 | 0.04 | +0.00 | buy |
| Motley Fool Wealth Management, LLC | 200,046 | 195,935 | -4,111 | 1.10 | 1.18 | +0.08 | sell |
| Treasurer of the State of North Carolina | 216,293 | 194,594 | -21,699 | 0.10 | 0.10 | -0.00 | sell |
| NZS Capital, LLC | 155,143 | 191,374 | +36,231 | 0.69 | 0.93 | +0.25 | buy |
| Chevy Chase Trust Holdings, LLC | 184,291 | 182,644 | -1,647 | 0.06 | 0.07 | +0.00 | sell |
| Rockefeller Capital Management L.P. | 174,523 | 176,721 | +2,198 | 0.05 | 0.06 | +0.01 | buy |
| CWM, LLC | 121,133 | 169,274 | +48,141 | 0.06 | 0.09 | +0.03 | buy |
| AVIVA PLC | 112,131 | 166,897 | +54,766 | 0.04 | 0.05 | +0.02 | buy |
| Qube Research & Technologies Ltd | 14,542 | 164,803 | +150,261 | 0.00 | 0.04 | +0.03 | buy |
| FIDUCIARY TRUST CO | 219,045 | 163,045 | -56,000 | 0.36 | 0.29 | -0.07 | sell |
| TD ASSET MANAGEMENT INC | 142,538 | 162,137 | +19,599 | 0.01 | 0.02 | +0.00 | buy |
| Squarepoint Ops LLC | 8,996 | 153,876 | +144,880 | 0.00 | 0.07 | +0.06 | buy |
| VAN ECK ASSOCIATES CORP | 233,246 | 152,160 | -81,086 | 0.04 | 0.03 | -0.01 | sell |
| WASHINGTON UNIVERSITY | 150,000 | 150,000 | 0 | 5.91 | 8.11 | +2.20 | hold |