| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 166,200 | 328,485 | +162,285 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,464,237 | 1,575,594 | +111,357 | 0.00 | 0.00 | -0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 217,006 | 327,127 | +110,121 | 0.00 | 0.00 | -0.00 | buy |
| JANUS HENDERSON GROUP PLC | 2,080,367 | 2,121,654 | +41,287 | 0.02 | 0.01 | -0.01 | buy |
| Qube Research & Technologies Ltd | 0 | 24,993 | +24,993 | 0.00 | 0.00 | +0.00 | buy |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0 | 24,800 | +24,800 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 1,031,826 | 1,053,314 | +21,488 | 0.00 | 0.00 | -0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 67,384 | 86,310 | +18,926 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 1,974,452 | 1,990,853 | +16,401 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 15,305 | +15,305 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 573,891 | 589,075 | +15,184 | 0.00 | 0.00 | -0.00 | buy |
| Creative Planning | 0 | 14,443 | +14,443 | 0.00 | 0.00 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 0 | 13,403 | +13,403 | 0.00 | 0.01 | +0.01 | buy |
| Trexquant Investment LP | 0 | 11,143 | +11,143 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 9,065 | +9,065 | 0.00 | 0.02 | +0.02 | buy |
| STRS OHIO | 32,800 | 41,800 | +9,000 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 59,710 | 67,793 | +8,083 | 0.00 | 0.00 | -0.00 | buy |
| AlphaQuest LLC | 4,046 | 11,662 | +7,616 | 0.01 | 0.01 | +0.00 | buy |
| Allspring Global Investments Holdings, LLC | 11,124 | 17,020 | +5,896 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 11,504 | 16,691 | +5,187 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3,324 | 8,234 | +4,910 | 0.00 | 0.00 | +0.00 | buy |
| WCG Wealth Advisors LLC | 24,030 | 28,830 | +4,800 | 0.03 | 0.02 | -0.01 | buy |
| MACKENZIE FINANCIAL CORP | 14,500 | 18,396 | +3,896 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 0 | 1,787 | +1,787 | 0.00 | 0.00 | +0.00 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 38,623 | 40,163 | +1,540 | 0.02 | 0.01 | -0.01 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0 | 746 | +746 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 14,175 | 14,799 | +624 | 0.00 | 0.00 | -0.00 | buy |
| US BANCORP \DE\ | 2,658 | 3,151 | +493 | 0.00 | 0.00 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 40,624 | 41,023 | +399 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 4,820 | 5,154 | +334 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 0 | 198 | +198 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 785 | 958 | +173 | 0.00 | 0.00 | -0.00 | buy |
| Daiwa Securities Group Inc. | 0 | 150 | +150 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 0 | 131 | +131 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 721 | 852 | +131 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 14,743 | 14,870 | +127 | 0.00 | 0.00 | -0.00 | buy |
| Hughes Financial Services, LLC | 0 | 49 | +49 | 0.00 | 0.00 | +0.00 | buy |
| CoreCap Advisors, LLC | 0 | 48 | +48 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 40 | +40 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 36 | +36 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 33 | +33 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 22,950 | 22,970 | +20 | 0.00 | 0.00 | -0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 0 | 20 | +20 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,246 | 1,258 | +12 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 130 | 142 | +12 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 2,417 | 2,417 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD ASSET MANAGEMENT INC | 47,788 | 47,788 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 16,222 | 16,222 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 12,770 | 12,770 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MPM ASSET MANAGEMENT LLC | 4,381,062 | 4,381,062 | 0 | 60.89 | 57.04 | -3.86 | hold |
| BAKER BROS. ADVISORS LP | 4,865,819 | 4,865,819 | 0 | 0.90 | 0.49 | -0.41 | hold |
| PRIVATE TRUST CO NA | 1,013 | 1,013 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MOORE CAPITAL MANAGEMENT, LP | 105,000 | 105,000 | 0 | 0.03 | 0.03 | -0.00 | hold |
| StepStone Group LP | 761,277 | 761,277 | 0 | 11.51 | 7.07 | -4.44 | hold |
| MetLife Investment Management, LLC | 16,329 | 16,329 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Swiss National Bank | 32,800 | 32,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KLP KAPITALFORVALTNING AS | 2,100 | 2,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Nan Fung Group Holdings Ltd | 49,082 | 49,082 | 0 | 0.73 | 0.36 | -0.36 | hold |
| 5AM Venture Management, LLC | 4,408,379 | 4,408,379 | 0 | 18.19 | 15.07 | -3.12 | hold |
| TCG Crossover Management, LLC | 584,955 | 584,955 | 0 | 0.99 | 0.72 | -0.27 | hold |
| Fortitude Family Office, LLC | 37 | 37 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 4,924 | 4,924 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Merck & Co., Inc. | 1,739,768 | 1,739,768 | 0 | 11.66 | 9.57 | -2.08 | hold |
| FRANKLIN RESOURCES INC | 16,290 | 16,290 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Legal & General Group Plc | 19,899 | 19,899 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,877 | 8,877 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EverSource Wealth Advisors, LLC | 14 | 0 | -14 | 0.00 | 0.00 | -0.00 | sell |
| Parallel Advisors, LLC | 16 | 0 | -16 | 0.00 | 0.00 | -0.00 | sell |
| IFP Advisors, Inc | 87 | 64 | -23 | 0.00 | 0.00 | -0.00 | sell |
| Amundi | 54 | 12 | -42 | 0.00 | 0.00 | -0.00 | sell |
| Smartleaf Asset Management LLC | 281 | 207 | -74 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 56,557 | 56,472 | -85 | 0.00 | 0.00 | -0.00 | sell |
| True Wealth Design, LLC | 93 | 0 | -93 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 127 | 27 | -100 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 12,276 | 12,096 | -180 | 0.00 | 0.00 | -0.00 | sell |
| C M BIDWELL & ASSOCIATES LTD | 212 | 29 | -183 | 0.00 | 0.00 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 28,032 | 27,792 | -240 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 470 | 161 | -309 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 1,546 | 1,192 | -354 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 792 | 426 | -366 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 7,931 | 7,541 | -390 | 0.01 | 0.01 | -0.01 | sell |
| RHUMBLINE ADVISERS | 36,731 | 36,113 | -618 | 0.00 | 0.00 | -0.00 | sell |
| Cornerstone Investment Partners, LLC | 11,889 | 10,943 | -946 | 0.01 | 0.00 | -0.01 | sell |
| FEDERATED HERMES, INC. | 99,814 | 98,720 | -1,094 | 0.00 | 0.00 | -0.00 | sell |
| FIRST TRUST ADVISORS LP | 73,749 | 72,489 | -1,260 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 19,878 | 18,586 | -1,292 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 101,358 | 100,060 | -1,298 | 0.00 | 0.00 | -0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 212,717 | 210,873 | -1,844 | 0.01 | 0.01 | -0.01 | sell |
| UBS Group AG | 53,091 | 51,039 | -2,052 | 0.00 | 0.00 | -0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 35,750 | 33,593 | -2,157 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 21,740 | 19,504 | -2,236 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 17,259 | 15,002 | -2,257 | 0.00 | 0.00 | -0.00 | sell |
| State of Wyoming | 6,037 | 3,280 | -2,757 | 0.01 | 0.00 | -0.01 | sell |
| VIRTUS ADVISERS, LLC | 3,924 | 0 | -3,924 | 0.03 | 0.00 | -0.03 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 197,127 | 192,717 | -4,410 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 318,177 | 310,187 | -7,990 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 504,979 | 494,388 | -10,591 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 51,365 | 39,651 | -11,714 | 0.00 | 0.00 | -0.00 | sell |