| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Invesco Ltd. | 61,397 | 537,548 | +476,151 | 0.00 | 0.01 | +0.01 | buy |
| NORGES BANK | 0 | 346,969 | +346,969 | 0.00 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 630,852 | 942,999 | +312,147 | 0.02 | 0.03 | +0.01 | buy |
| Polar Capital Holdings Plc | 0 | 279,131 | +279,131 | 0.00 | 0.26 | +0.26 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 220,008 | +220,008 | 0.00 | 0.01 | +0.01 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 662 | 218,898 | +218,236 | 0.00 | 0.24 | +0.24 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 815,739 | 1,015,480 | +199,741 | 0.41 | 0.48 | +0.07 | buy |
| FMR LLC | 2,160,943 | 2,316,907 | +155,964 | 0.04 | 0.03 | -0.00 | buy |
| STATE STREET CORP | 884,238 | 1,026,443 | +142,205 | 0.01 | 0.01 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 128,254 | 237,315 | +109,061 | 0.02 | 0.04 | +0.01 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 7,388 | 107,409 | +100,021 | 0.00 | 0.01 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 650,904 | 748,039 | +97,135 | 0.01 | 0.01 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 28,134 | 122,227 | +94,093 | 0.01 | 0.04 | +0.03 | buy |
| MARSHALL WACE, LLP | 45,149 | 137,008 | +91,859 | 0.02 | 0.04 | +0.02 | buy |
| ADAR1 Capital Management, LLC | 1,500 | 74,253 | +72,753 | 0.03 | 1.17 | +1.14 | buy |
| Hood River Capital Management LLC | 358,618 | 425,167 | +66,549 | 1.16 | 1.03 | -0.13 | buy |
| Neuberger Berman Group LLC | 25,960 | 89,468 | +63,508 | 0.01 | 0.02 | +0.01 | buy |
| ORBIMED ADVISORS LLC | 172,500 | 230,100 | +57,600 | 1.21 | 1.46 | +0.25 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 56,840 | +56,840 | 0.00 | 0.03 | +0.03 | buy |
| RAYMOND JAMES FINANCIAL INC | 5,320 | 61,980 | +56,660 | 0.00 | 0.01 | +0.01 | buy |
| FRANKLIN RESOURCES INC | 276,123 | 327,124 | +51,001 | 0.02 | 0.02 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 143,082 | 188,409 | +45,327 | 0.03 | 0.03 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 27,700 | 71,518 | +43,818 | 0.00 | 0.01 | +0.00 | buy |
| First Turn Management, LLC | 42,441 | 83,528 | +41,087 | 1.53 | 2.99 | +1.46 | buy |
| Squarepoint Ops LLC | 2,010 | 42,501 | +40,491 | 0.00 | 0.03 | +0.03 | buy |
| Nuveen, LLC | 72,043 | 108,032 | +35,989 | 0.01 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 31,220 | 64,295 | +33,075 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 0 | 27,981 | +27,981 | 0.00 | 0.01 | +0.01 | buy |
| Russell Investments Group, Ltd. | 23,112 | 50,944 | +27,832 | 0.01 | 0.01 | +0.01 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 0 | 27,058 | +27,058 | 0.00 | 0.06 | +0.06 | buy |
| PEREGRINE CAPITAL MANAGEMENT LLC | 0 | 25,790 | +25,790 | 0.00 | 0.28 | +0.28 | buy |
| WCM INVESTMENT MANAGEMENT, LLC | 0 | 24,739 | +24,739 | 0.00 | 0.02 | +0.02 | buy |
| CASTLEARK MANAGEMENT LLC | 0 | 24,390 | +24,390 | 0.00 | 0.22 | +0.22 | buy |
| Qube Research & Technologies Ltd | 128,228 | 152,475 | +24,247 | 0.06 | 0.06 | -0.00 | buy |
| UBS Group AG | 108,446 | 131,046 | +22,600 | 0.01 | 0.01 | +0.00 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 53,365 | 74,207 | +20,842 | 0.18 | 0.23 | +0.05 | buy |
| MORGAN STANLEY | 833,491 | 854,112 | +20,621 | 0.02 | 0.02 | -0.00 | buy |
| Man Group plc | 3,173 | 21,164 | +17,991 | 0.00 | 0.01 | +0.01 | buy |
| CITIGROUP INC | 5,646 | 23,599 | +17,953 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 11,614 | 27,889 | +16,275 | 0.00 | 0.00 | +0.00 | buy |
| Affinity Asset Advisors, LLC | 170,000 | 185,000 | +15,000 | 3.21 | 3.03 | -0.18 | buy |
| NORTHERN TRUST CORP | 227,934 | 240,887 | +12,953 | 0.01 | 0.01 | -0.00 | buy |
| Atika Capital Management LLC | 0 | 12,900 | +12,900 | 0.00 | 0.43 | +0.43 | buy |
| BANK OF AMERICA CORP /DE/ | 534,604 | 546,930 | +12,326 | 0.01 | 0.01 | -0.00 | buy |
| Allianz Asset Management GmbH | 14,030 | 25,744 | +11,714 | 0.01 | 0.01 | +0.00 | buy |
| SEI INVESTMENTS CO | 29,525 | 40,117 | +10,592 | 0.01 | 0.01 | +0.00 | buy |
| READYSTATE ASSET MANAGEMENT LP | 0 | 10,548 | +10,548 | 0.00 | 0.14 | +0.14 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 10,306 | +10,306 | 0.00 | 0.02 | +0.02 | buy |
| Handelsbanken Fonder AB | 0 | 9,840 | +9,840 | 0.00 | 0.01 | +0.01 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 949,225 | 959,048 | +9,823 | 2.25 | 1.86 | -0.39 | buy |
| MetLife Investment Management, LLC | 80,930 | 90,543 | +9,613 | 0.13 | 0.14 | +0.00 | buy |
| University of Wisconsin Foundation | 25,215 | 34,730 | +9,515 | 7.21 | 9.21 | +1.99 | buy |
| Nicholas Investment Partners, LP | 3,948 | 13,113 | +9,165 | 0.09 | 0.25 | +0.16 | buy |
| Alyeska Investment Group, L.P. | 72,178 | 80,846 | +8,668 | 0.07 | 0.07 | +0.00 | buy |
| Cinctive Capital Management LP | 0 | 8,300 | +8,300 | 0.00 | 0.11 | +0.11 | buy |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 0 | 8,020 | +8,020 | 0.00 | 0.06 | +0.06 | buy |
| CITADEL ADVISORS LLC | 0 | 7,331 | +7,331 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 0 | 7,093 | +7,093 | 0.00 | 0.00 | +0.00 | buy |
| ROYCE & ASSOCIATES LP | 0 | 6,544 | +6,544 | 0.00 | 0.02 | +0.02 | buy |
| DEUTSCHE BANK AG\ | 57,779 | 64,263 | +6,484 | 0.01 | 0.01 | +0.00 | buy |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 1,800 | 8,060 | +6,260 | 0.00 | 0.02 | +0.01 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 4,049 | 9,280 | +5,231 | 0.00 | 0.01 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 0 | 5,140 | +5,140 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 286,644 | 291,689 | +5,045 | 0.10 | 0.09 | -0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 7,194 | 12,046 | +4,852 | 0.01 | 0.01 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 68,383 | 72,952 | +4,569 | 0.04 | 0.04 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 215,447 | 220,008 | +4,561 | 0.01 | 0.01 | -0.00 | buy |
| Carl P. Sherr & Co., LLC | 972 | 4,889 | +3,917 | 0.15 | 0.69 | +0.54 | buy |
| HighVista Strategies LLC | 26,323 | 30,210 | +3,887 | 2.34 | 2.31 | -0.04 | buy |
| SG Americas Securities, LLC | 852 | 4,321 | +3,469 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 42,163 | 45,370 | +3,207 | 0.01 | 0.01 | +0.00 | buy |
| HOMESTEAD ADVISERS CORP | 3,300 | 6,500 | +3,200 | 0.03 | 0.05 | +0.03 | buy |
| NEW YORK LIFE INVESTMENT MANAGEMENT LLC | 0 | 3,137 | +3,137 | 0.00 | 0.01 | +0.01 | buy |
| PFM Health Sciences, LP | 35,438 | 38,575 | +3,137 | 1.20 | 1.12 | -0.08 | buy |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 12,473 | 15,432 | +2,959 | 0.05 | 0.05 | +0.00 | buy |
| FIFTH THIRD BANCORP | 3,589 | 6,359 | +2,770 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 2,768 | +2,768 | 0.00 | 0.09 | +0.09 | buy |
| Scientech Research LLC | 669 | 3,378 | +2,709 | 0.18 | 0.92 | +0.74 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 8,749 | 11,441 | +2,692 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 2,621 | +2,621 | 0.00 | 0.01 | +0.01 | buy |
| Legato Capital Management LLC | 670 | 3,171 | +2,501 | 0.02 | 0.09 | +0.07 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 2,183 | +2,183 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 0 | 2,170 | +2,170 | 0.00 | 0.01 | +0.01 | buy |
| CAPTRUST FINANCIAL ADVISORS | 0 | 2,153 | +2,153 | 0.00 | 0.00 | +0.00 | buy |
| WEXFORD CAPITAL LP | 0 | 2,000 | +2,000 | 0.00 | 0.09 | +0.09 | buy |
| Polymer Capital Management (US) LLC | 0 | 1,940 | +1,940 | 0.00 | 0.10 | +0.10 | buy |
| ROYAL BANK OF CANADA | 4,133 | 6,065 | +1,932 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Quantitative Investments LLC | 1,253 | 3,173 | +1,920 | 0.07 | 0.17 | +0.10 | buy |
| Magnetar Financial LLC | 0 | 1,911 | +1,911 | 0.00 | 0.01 | +0.01 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 1,880 | +1,880 | 0.00 | 0.00 | +0.00 | buy |
| Federation des caisses Desjardins du Quebec | 0 | 1,831 | +1,831 | 0.00 | 0.00 | +0.00 | buy |
| Erste Asset Management GmbH | 10,500 | 12,200 | +1,700 | 0.03 | 0.03 | +0.01 | buy |
| GROUP ONE TRADING LLC | 129 | 1,666 | +1,537 | 0.00 | 0.02 | +0.01 | buy |
| UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO | 0 | 1,525 | +1,525 | 0.00 | 0.06 | +0.06 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 0 | 1,331 | +1,331 | 0.00 | 0.03 | +0.03 | buy |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | 0 | 1,327 | +1,327 | 0.00 | 0.03 | +0.03 | buy |
| Mitsubishi UFJ Trust & Banking Corp | 0 | 1,317 | +1,317 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 16,168 | 17,478 | +1,310 | 0.08 | 0.07 | -0.01 | buy |
| Ikarian Capital, LLC | 71,581 | 72,842 | +1,261 | 3.30 | 3.99 | +0.69 | buy |
| GUGGENHEIM CAPITAL LLC | 2,670 | 3,846 | +1,176 | 0.01 | 0.01 | +0.00 | buy |