| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 275,675 | +275,675 | 0.00 | 0.17 | +0.17 | buy |
| BlackRock, Inc. | 2,470,845 | 2,734,305 | +263,460 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 363,799 | 576,456 | +212,657 | 0.00 | 0.00 | +0.00 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 195,486 | +195,486 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 136,966 | 259,219 | +122,253 | 0.00 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 108,307 | 227,485 | +119,178 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 504,373 | 602,028 | +97,655 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 518,228 | 612,793 | +94,565 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 0 | 91,656 | +91,656 | 0.00 | 0.00 | +0.00 | buy |
| Eversept Partners, LP | 100,198 | 183,663 | +83,465 | 0.16 | 0.32 | +0.16 | buy |
| Longbow Finance SA | 0 | 82,336 | +82,336 | 0.00 | 0.34 | +0.34 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 4,052 | 86,371 | +82,319 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 1,427,568 | 1,497,293 | +69,725 | 0.00 | 0.00 | +0.00 | buy |
| ALERUS FINANCIAL NA | 0 | 54,891 | +54,891 | 0.00 | 0.08 | +0.08 | buy |
| MORGAN STANLEY | 0 | 51,207 | +51,207 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 47,006 | +47,006 | 0.00 | 0.02 | +0.02 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 39,413 | +39,413 | 0.00 | 0.03 | +0.03 | buy |
| HighVista Strategies LLC | 173,595 | 211,511 | +37,916 | 1.18 | 1.57 | +0.38 | buy |
| TWO SIGMA INVESTMENTS, LP | 12,720 | 48,652 | +35,932 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 154,398 | 186,037 | +31,639 | 0.00 | 0.00 | +0.00 | buy |
| GREAT LAKES ADVISORS, LLC | 0 | 30,410 | +30,410 | 0.00 | 0.01 | +0.01 | buy |
| Swiss National Bank | 0 | 30,200 | +30,200 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 22,966 | 52,142 | +29,176 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 29,102 | +29,102 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 27,600 | +27,600 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 0 | 22,925 | +22,925 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 17,325 | +17,325 | 0.00 | 0.00 | +0.00 | buy |
| GREAT POINT PARTNERS LLC | 300,000 | 317,221 | +17,221 | 1.81 | 2.43 | +0.61 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 1,041 | 16,378 | +15,337 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 9,931 | 23,955 | +14,024 | 0.00 | 0.01 | +0.00 | buy |
| HOLLENCREST CAPITAL MANAGEMENT | 0 | 13,722 | +13,722 | 0.00 | 0.03 | +0.03 | buy |
| D. E. Shaw & Co., Inc. | 0 | 13,518 | +13,518 | 0.00 | 0.00 | +0.00 | buy |
| Knott David M Jr | 0 | 12,965 | +12,965 | 0.00 | 0.22 | +0.22 | buy |
| SEI INVESTMENTS CO | 0 | 12,611 | +12,611 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 12,260 | +12,260 | 0.00 | 0.01 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 0 | 11,513 | +11,513 | 0.00 | 0.09 | +0.09 | buy |
| WELLS FARGO & COMPANY/MN | 8,623 | 19,537 | +10,914 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 17,103 | 27,789 | +10,686 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 5,569 | 15,719 | +10,150 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 16,618 | 26,540 | +9,922 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 45,457 | 54,979 | +9,522 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 186,095 | 195,486 | +9,391 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 1,723 | 9,838 | +8,115 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 7,018 | +7,018 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 15,359 | 21,972 | +6,613 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 6,252 | +6,252 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 52,640 | 58,891 | +6,251 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 0 | 5,956 | +5,956 | 0.00 | 0.01 | +0.01 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 13,229 | 18,622 | +5,393 | 0.00 | 0.00 | +0.00 | buy |
| Persistent Asset Partners Ltd | 0 | 4,926 | +4,926 | 0.00 | 0.05 | +0.05 | buy |
| BARCLAYS PLC | 4,530 | 8,928 | +4,398 | 0.00 | 0.00 | +0.00 | buy |
| KLP KAPITALFORVALTNING AS | 0 | 3,400 | +3,400 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 6,100 | 9,400 | +3,300 | 0.00 | 0.00 | +0.00 | buy |
| JENNISON ASSOCIATES LLC | 538,216 | 540,902 | +2,686 | 0.01 | 0.01 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 2,630 | +2,630 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 11,104 | 13,469 | +2,365 | 0.00 | 0.00 | +0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0 | 1,400 | +1,400 | 0.00 | 0.00 | +0.00 | buy |
| Pinnacle Wealth Planning Services, Inc. | 0 | 1,314 | +1,314 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 10,729 | 12,001 | +1,272 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 9,170 | 10,306 | +1,136 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 660 | +660 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 1,562 | 2,031 | +469 | 0.00 | 0.00 | +0.00 | buy |
| FIFTH THIRD BANCORP | 0 | 390 | +390 | 0.00 | 0.00 | +0.00 | buy |
| State of Wyoming | 0 | 198 | +198 | 0.00 | 0.00 | +0.00 | buy |
| Global Retirement Partners, LLC | 0 | 189 | +189 | 0.00 | 0.00 | +0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 0 | 65 | +65 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 162 | 196 | +34 | 0.00 | 0.00 | +0.00 | buy |
| WPG Advisers, LLC | 0 | 18 | +18 | 0.00 | 0.00 | +0.00 | buy |
| Rossby Financial, LCC | 0 | 14 | +14 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 1 | 2 | +1 | 0.00 | 0.00 | +0.00 | buy |
| MassMutual Private Wealth & Trust, FSB | 54 | 54 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BAKER BROS. ADVISORS LP | 200,000 | 200,000 | 0 | 0.03 | 0.03 | +0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 2,208,604 | 2,208,604 | 0 | 0.58 | 0.62 | +0.05 | hold |
| Alyeska Investment Group, L.P. | 863,947 | 863,947 | 0 | 0.06 | 0.07 | +0.01 | hold |
| Nantahala Capital Management, LLC | 1,052,894 | 1,052,894 | 0 | 1.62 | 2.06 | +0.44 | hold |
| ACUTA CAPITAL PARTNERS, LLC | 28,919 | 28,919 | 0 | 0.51 | 0.65 | +0.15 | hold |
| Vivo Capital, LLC | 800,000 | 800,000 | 0 | 1.64 | 2.37 | +0.73 | hold |
| Caligan Partners LP | 1,438,070 | 1,438,070 | 0 | 2.45 | 2.25 | -0.20 | hold |
| Integral Health Asset Management, LLC | 150,000 | 150,000 | 0 | 0.20 | 0.20 | +0.00 | hold |
| Nan Fung Group Holdings Ltd | 630,657 | 630,657 | 0 | 12.82 | 15.57 | +2.74 | hold |
| Commodore Capital LP | 1,500,000 | 1,500,000 | 0 | 2.14 | 2.90 | +0.76 | hold |
| Deep Track Capital, LP | 3,352,804 | 3,352,804 | 0 | 1.71 | 1.60 | -0.10 | hold |
| Boxer Capital Management, LLC | 70,000 | 70,000 | 0 | 0.23 | 0.17 | -0.06 | hold |
| Police & Firemen's Retirement System of New Jersey | 6,041 | 6,041 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MEYER HANDELMAN CO | 15,094 | 15,094 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Sterling Capital Management LLC | 368 | 274 | -94 | 0.00 | 0.00 | -0.00 | sell |
| Focus Partners Wealth | 19,815 | 19,573 | -242 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 1,661 | 762 | -899 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 923,694 | 921,471 | -2,223 | 0.04 | 0.05 | +0.01 | sell |
| FEDERATED HERMES, INC. | 5,000 | 2,500 | -2,500 | 0.00 | 0.00 | -0.00 | sell |
| Calamos Advisors LLC | 24,063 | 19,198 | -4,865 | 0.00 | 0.00 | -0.00 | sell |
| STRS OHIO | 5,100 | 0 | -5,100 | 0.00 | 0.00 | -0.00 | sell |
| Soleus Capital Management, L.P. | 10,000 | 0 | -10,000 | 0.01 | 0.00 | -0.01 | sell |
| Opaleye Management Inc. | 14,506 | 0 | -14,506 | 0.05 | 0.00 | -0.05 | sell |
| STEMPOINT CAPITAL LP | 50,000 | 31,785 | -18,215 | 0.24 | 0.18 | -0.06 | sell |
| FMR LLC | 222,508 | 188,907 | -33,601 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 72,067 | 33,893 | -38,174 | 0.00 | 0.00 | -0.00 | sell |