| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 2,143,083 | 2,565,399 | +422,316 | 0.69 | 0.69 | +0.00 | buy |
| CITADEL ADVISORS LLC | 551,939 | 865,970 | +314,031 | 0.32 | 0.41 | +0.09 | buy |
| MILLENNIUM MANAGEMENT LLC | 268,604 | 429,844 | +161,240 | 0.15 | 0.21 | +0.06 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 138,637 | 297,113 | +158,476 | 0.15 | 0.28 | +0.12 | buy |
| FRANKLIN RESOURCES INC | 137,197 | 279,803 | +142,606 | 0.02 | 0.04 | +0.02 | buy |
| Clearbridge Investments, LLC | 664,368 | 772,866 | +108,498 | 0.34 | 0.35 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 9,637 | 89,296 | +79,659 | 0.01 | 0.11 | +0.10 | buy |
| Hudson Bay Capital Management LP | 0 | 67,923 | +67,923 | 0.00 | 0.25 | +0.25 | buy |
| Artia Global Partners LP | 11,311 | 78,311 | +67,000 | 1.96 | 11.10 | +9.14 | buy |
| BNP Paribas Asset Management Holding S.A. | 25,370 | 87,414 | +62,044 | 0.04 | 0.12 | +0.08 | buy |
| LAZARD ASSET MANAGEMENT LLC | 70,250 | 127,488 | +57,238 | 0.06 | 0.10 | +0.03 | buy |
| AMERICAN CENTURY COMPANIES INC | 148,852 | 205,906 | +57,054 | 0.05 | 0.06 | +0.01 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,407 | 53,835 | +52,428 | 0.00 | 0.01 | +0.01 | buy |
| MARSHALL WACE, LLP | 126,774 | 177,724 | +50,950 | 0.10 | 0.12 | +0.02 | buy |
| Ensign Peak Advisors, Inc | 45,952 | 93,336 | +47,384 | 0.05 | 0.09 | +0.04 | buy |
| AMERIPRISE FINANCIAL INC | 68,876 | 111,195 | +42,319 | 0.01 | 0.02 | +0.00 | buy |
| Checkpoint Capital L.P. | 115,000 | 149,977 | +34,977 | 37.34 | 38.52 | +1.18 | buy |
| BRAIDWELL LP | 160,849 | 194,491 | +33,642 | 3.35 | 3.67 | +0.32 | buy |
| Tri Locum Partners LP | 17,844 | 47,793 | +29,949 | 5.42 | 7.99 | +2.58 | buy |
| Patient Square Capital LP | 0 | 29,000 | +29,000 | 0.00 | 5.76 | +5.76 | buy |
| CAISSE DE DEPOT ET PLACEMENT DU QUEBEC | 62,074 | 90,895 | +28,821 | 0.08 | 0.11 | +0.03 | buy |
| PGGM Investments | 48,799 | 76,699 | +27,900 | 0.39 | 0.73 | +0.34 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 570 | 24,419 | +23,849 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 0 | 23,628 | +23,628 | 0.00 | 0.01 | +0.01 | buy |
| MOORE CAPITAL MANAGEMENT, LP | 25,000 | 47,000 | +22,000 | 0.49 | 0.52 | +0.02 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,873 | 23,790 | +21,917 | 0.00 | 0.02 | +0.02 | buy |
| Quadrature Capital Ltd | 0 | 20,501 | +20,501 | 0.00 | 0.19 | +0.19 | buy |
| Aberdeen Group plc | 54,590 | 70,293 | +15,703 | 0.06 | 0.07 | +0.00 | buy |
| JENNISON ASSOCIATES LLC | 249,461 | 264,647 | +15,186 | 0.10 | 0.09 | -0.02 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 0 | 14,993 | +14,993 | 0.00 | 0.09 | +0.09 | buy |
| FEDERATED HERMES, INC. | 108,945 | 123,659 | +14,714 | 0.14 | 0.13 | -0.01 | buy |
| Soleus Capital Management, L.P. | 28,940 | 42,876 | +13,936 | 1.34 | 1.63 | +0.29 | buy |
| Tower Research Capital LLC (TRC) | 5,404 | 19,339 | +13,935 | 0.10 | 0.29 | +0.19 | buy |
| Optiver Holding B.V. | 3,795 | 17,394 | +13,599 | 0.09 | 0.26 | +0.17 | buy |
| Capital World Investors | 1,937,992 | 1,951,082 | +13,090 | 0.19 | 0.16 | -0.03 | buy |
| Legal & General Group Plc | 114,094 | 125,809 | +11,715 | 0.02 | 0.02 | -0.00 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 113,743 | 125,383 | +11,640 | 1.34 | 1.21 | -0.13 | buy |
| Thematics Asset Management | 0 | 11,576 | +11,576 | 0.00 | 0.29 | +0.29 | buy |
| NORTHERN TRUST CORP | 52,426 | 62,932 | +10,506 | 0.00 | 0.00 | +0.00 | buy |
| SIH Partners, LLLP | 2,006 | 11,481 | +9,475 | 0.10 | 0.60 | +0.50 | buy |
| Allspring Global Investments Holdings, LLC | 176,450 | 184,987 | +8,537 | 0.17 | 0.17 | -0.01 | buy |
| Prosight Management, LP | 13,700 | 22,000 | +8,300 | 2.66 | 2.96 | +0.29 | buy |
| TimesSquare Capital Management, LLC | 125,295 | 133,580 | +8,285 | 1.19 | 1.06 | -0.13 | buy |
| LMR Partners LLP | 13,130 | 20,800 | +7,670 | 0.16 | 0.18 | +0.02 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 79,468 | 86,861 | +7,393 | 0.02 | 0.01 | -0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 66,873 | 72,588 | +5,715 | 0.01 | 0.01 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 4,933 | +4,933 | 0.00 | 0.07 | +0.07 | buy |
| NOMURA HOLDINGS INC | 0 | 4,629 | +4,629 | 0.00 | 0.02 | +0.02 | buy |
| Candriam S.C.A. | 41,280 | 45,567 | +4,287 | 0.15 | 0.14 | -0.01 | buy |
| Fiera Capital Corp | 154,416 | 158,474 | +4,058 | 0.33 | 0.30 | -0.03 | buy |
| Engineers Gate Manager LP | 17,339 | 21,104 | +3,765 | 0.17 | 0.14 | -0.03 | buy |
| DIMENSIONAL FUND ADVISORS LP | 32,241 | 35,993 | +3,752 | 0.00 | 0.00 | -0.00 | buy |
| PineBridge Investments, L.P. | 73,175 | 76,741 | +3,566 | 0.34 | 0.34 | -0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 59,694 | 63,243 | +3,549 | 0.03 | 0.03 | -0.00 | buy |
| Independent Advisor Alliance | 4,477 | 7,986 | +3,509 | 0.09 | 0.13 | +0.04 | buy |
| SWS Partners | 0 | 3,270 | +3,270 | 0.00 | 0.49 | +0.49 | buy |
| Campbell & CO Investment Adviser LLC | 2,328 | 5,535 | +3,207 | 0.11 | 0.19 | +0.09 | buy |
| Federation des caisses Desjardins du Quebec | 2,921 | 6,015 | +3,094 | 0.01 | 0.01 | +0.01 | buy |
| ROYAL BANK OF CANADA | 38,306 | 41,314 | +3,008 | 0.01 | 0.00 | -0.00 | buy |
| Trexquant Investment LP | 6,059 | 9,008 | +2,949 | 0.04 | 0.06 | +0.01 | buy |
| MML INVESTORS SERVICES, LLC | 12,506 | 15,380 | +2,874 | 0.02 | 0.02 | -0.00 | buy |
| Sivik Global Healthcare LLC | 0 | 2,500 | +2,500 | 0.00 | 0.62 | +0.62 | buy |
| Eagle Health Investments LP | 74,990 | 77,430 | +2,440 | 11.53 | 10.53 | -0.99 | buy |
| PANAGORA ASSET MANAGEMENT INC | 0 | 2,427 | +2,427 | 0.00 | 0.01 | +0.01 | buy |
| XY Capital Ltd | 0 | 2,276 | +2,276 | 0.00 | 0.86 | +0.86 | buy |
| Cambridge Investment Research Advisors, Inc. | 985 | 3,214 | +2,229 | 0.00 | 0.01 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0 | 2,191 | +2,191 | 0.00 | 0.03 | +0.03 | buy |
| First Turn Management, LLC | 41,911 | 43,953 | +2,042 | 5.00 | 4.52 | -0.48 | buy |
| Alyeska Investment Group, L.P. | 0 | 1,836 | +1,836 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 38,050 | 39,753 | +1,703 | 0.09 | 0.08 | -0.02 | buy |
| Assenagon Asset Management S.A. | 110,390 | 112,057 | +1,667 | 0.12 | 0.10 | -0.02 | buy |
| AXA S.A. | 29,483 | 31,133 | +1,650 | 0.06 | 0.05 | -0.01 | buy |
| Orion Porfolio Solutions, LLC | 8,736 | 10,294 | +1,558 | 0.05 | 0.05 | -0.00 | buy |
| Varma Mutual Pension Insurance Co | 1,500 | 3,000 | +1,500 | 0.01 | 0.01 | +0.00 | buy |
| WESPAC Advisors SoCal, LLC | 0 | 1,495 | +1,495 | 0.00 | 0.18 | +0.18 | buy |
| Amundi | 6,351 | 7,766 | +1,415 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 3,283 | 4,611 | +1,328 | 0.01 | 0.01 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 206,700 | 208,000 | +1,300 | 2.94 | 2.88 | -0.06 | buy |
| D.A. DAVIDSON & CO. | 0 | 1,196 | +1,196 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 20,880 | 22,054 | +1,174 | 0.00 | 0.00 | -0.00 | buy |
| ADAR1 Capital Management, LLC | 600 | 1,759 | +1,159 | 0.07 | 0.16 | +0.09 | buy |
| SIMPLEX TRADING, LLC | 0 | 1,138 | +1,138 | 0.00 | 0.02 | +0.02 | buy |
| LEVEL FOUR ADVISORY SERVICES, LLC | 0 | 1,134 | +1,134 | 0.00 | 0.02 | +0.02 | buy |
| Callan Family Office, LLC | 362 | 1,452 | +1,090 | 0.02 | 0.03 | +0.01 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 1,198 | 2,251 | +1,053 | 0.02 | 0.03 | +0.01 | buy |
| SECTORAL ASSET MANAGEMENT INC | 3,103 | 4,085 | +982 | 1.43 | 1.49 | +0.06 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 14,905 | 15,855 | +950 | 0.01 | 0.01 | -0.00 | buy |
| STATE STREET CORP | 4,094 | 4,980 | +886 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 30,421 | 31,296 | +875 | 0.04 | 0.04 | -0.01 | buy |
| Valeo Financial Advisors, LLC | 429 | 1,303 | +874 | 0.01 | 0.02 | +0.01 | buy |
| MOODY ALDRICH PARTNERS LLC | 0 | 869 | +869 | 0.00 | 0.09 | +0.09 | buy |
| Pacer Advisors, Inc. | 0 | 857 | +857 | 0.00 | 0.00 | +0.00 | buy |
| TANDEM CAPITAL MANAGEMENT CORP /ADV | 0 | 817 | +817 | 0.00 | 0.23 | +0.23 | buy |
| Naviter Wealth, LLC | 0 | 800 | +800 | 0.00 | 0.05 | +0.05 | buy |
| Virtu Financial LLC | 0 | 795 | +795 | 0.00 | 0.02 | +0.02 | buy |
| BAROMETER CAPITAL MANAGEMENT INC. | 0 | 750 | +750 | 0.00 | 0.11 | +0.11 | buy |
| SteelPeak Wealth, LLC | 0 | 712 | +712 | 0.00 | 0.02 | +0.02 | buy |
| Erste Asset Management GmbH | 13,800 | 14,496 | +696 | 0.10 | 0.07 | -0.04 | buy |
| Vestmark Advisory Solutions, Inc. | 0 | 666 | +666 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 4,732 | 5,363 | +631 | 0.00 | 0.00 | -0.00 | buy |