| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 2,464,712 | 2,958,246 | +493,534 | 0.00 | 0.00 | +0.00 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 1,349,000 | 2,342,684 | +993,684 | 0.45 | 1.04 | +0.59 | buy |
| BAKER BROS. ADVISORS LP | 1,630,125 | 2,085,333 | +455,208 | 0.70 | 1.05 | +0.35 | buy |
| VANGUARD GROUP INC | 1,816,993 | 1,980,783 | +163,790 | 0.00 | 0.00 | +0.00 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 2,020,940 | 1,838,684 | -182,256 | 0.09 | 0.12 | +0.03 | sell |
| STATE STREET CORP | 1,316,977 | 1,827,523 | +510,546 | 0.00 | 0.01 | +0.00 | buy |
| MORGAN STANLEY | 923,040 | 1,511,687 | +588,647 | 0.00 | 0.01 | +0.00 | buy |
| CRCM LP | 1,842,651 | 1,072,374 | -770,277 | 31.52 | 31.01 | -0.51 | sell |
| Arbiter Partners Capital Management LLC | 1,035,897 | 1,035,597 | -300 | 41.99 | 47.70 | +5.71 | sell |
| Deep Track Capital, LP | 0 | 1,022,797 | +1,022,797 | 0.00 | 2.00 | +2.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 730,250 | 801,503 | +71,253 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 335,365 | 708,503 | +373,138 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 365,032 | 536,986 | +171,954 | 0.00 | 0.01 | +0.00 | buy |
| Alyeska Investment Group, L.P. | 0 | 442,500 | +442,500 | 0.00 | 0.11 | +0.11 | buy |
| RA CAPITAL MANAGEMENT, L.P. | 0 | 428,266 | +428,266 | 0.00 | 0.38 | +0.38 | buy |
| Sessa Capital IM, L.P. | 786,144 | 364,714 | -421,430 | 1.17 | 0.62 | -0.55 | sell |
| NORTHERN TRUST CORP | 340,482 | 341,427 | +945 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 422,655 | 326,845 | -95,810 | 0.02 | 0.01 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 251,492 | 270,827 | +19,335 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 294,835 | 267,560 | -27,275 | 0.02 | 0.03 | +0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 160,203 | 258,810 | +98,607 | 0.00 | 0.01 | +0.00 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 237,342 | +237,342 | 0.00 | 0.37 | +0.37 | buy |
| DIMENSIONAL FUND ADVISORS LP | 46,649 | 216,793 | +170,144 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 360,456 | 213,178 | -147,278 | 0.00 | 0.00 | -0.00 | sell |
| Carnegie Investment Counsel | 245,315 | 213,050 | -32,265 | 0.27 | 0.34 | +0.06 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 31,700 | 210,768 | +179,068 | 0.00 | 0.00 | +0.00 | buy |
| TCW GROUP INC | 233,213 | 197,313 | -35,900 | 0.12 | 0.12 | +0.01 | sell |
| FMR LLC | 108,792 | 163,244 | +54,452 | 0.00 | 0.00 | +0.00 | buy |
| Slow Capital, Inc. | 143,840 | 162,417 | +18,577 | 1.00 | 1.66 | +0.66 | buy |
| Douglas Lane & Associates, LLC | 168,316 | 161,624 | -6,692 | 0.14 | 0.19 | +0.05 | sell |
| BIT Capital GmbH | 0 | 156,263 | +156,263 | 0.00 | 0.58 | +0.58 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 152,626 | 152,574 | -52 | 0.03 | 0.05 | +0.02 | sell |
| Newtyn Management, LLC | 200,000 | 150,000 | -50,000 | 1.45 | 1.36 | -0.09 | sell |
| Voleon Capital Management LP | 61,575 | 147,906 | +86,331 | 0.09 | 0.27 | +0.18 | buy |
| FRANKLIN RESOURCES INC | 4,606 | 146,135 | +141,529 | 0.00 | 0.00 | +0.00 | buy |
| BRAIDWELL LP | 0 | 142,755 | +142,755 | 0.00 | 0.39 | +0.39 | buy |
| JPMORGAN CHASE & CO | 206,120 | 141,478 | -64,642 | 0.00 | 0.00 | +0.00 | sell |
| Invesco Ltd. | 136,545 | 137,967 | +1,422 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 130,907 | 135,808 | +4,901 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 94,006 | 125,658 | +31,652 | 0.00 | 0.00 | +0.00 | buy |
| Aberdeen Group plc | 269,440 | 124,928 | -144,512 | 0.03 | 0.02 | -0.01 | sell |
| 180 WEALTH ADVISORS, LLC | 118,861 | 115,047 | -3,814 | 0.86 | 1.12 | +0.26 | sell |
| CAPITAL FUND MANAGEMENT S.A. | 175,221 | 113,207 | -62,014 | 0.10 | 0.09 | -0.01 | sell |
| Reynders McVeigh Capital Management, LLC | 120,601 | 112,869 | -7,732 | 0.33 | 0.45 | +0.12 | sell |
| FIRST TRUST ADVISORS LP | 0 | 108,325 | +108,325 | 0.00 | 0.01 | +0.01 | buy |
| WIM INVESTMENT MANAGEMENT Ltd | 63,000 | 106,400 | +43,400 | 0.95 | 2.35 | +1.41 | buy |
| TWO SIGMA INVESTMENTS, LP | 147,032 | 101,449 | -45,583 | 0.01 | 0.01 | -0.00 | sell |
| Blue Water Life Science Advisors, LP | 0 | 99,000 | +99,000 | 0.00 | 5.32 | +5.32 | buy |
| T. Rowe Price Investment Management, Inc. | 0 | 86,613 | +86,613 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 103,100 | 85,300 | -17,800 | 0.01 | 0.01 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 66,408 | 81,476 | +15,068 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 59,300 | 72,300 | +13,000 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 67,634 | 70,850 | +3,216 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 58,012 | 68,577 | +10,565 | 0.01 | 0.01 | +0.00 | buy |
| Legal & General Group Plc | 67,021 | 68,349 | +1,328 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 49,691 | 67,534 | +17,843 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 67,427 | +67,427 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 54,202 | 65,336 | +11,134 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 59,145 | 61,611 | +2,466 | 0.00 | 0.00 | +0.00 | buy |
| Rafferty Asset Management, LLC | 43,009 | 61,284 | +18,275 | 0.01 | 0.02 | +0.01 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 0 | 55,855 | +55,855 | 0.00 | 0.02 | +0.02 | buy |
| ROYAL BANK OF CANADA | 61,735 | 54,335 | -7,400 | 0.00 | 0.00 | +0.00 | sell |
| Pier Capital, LLC | 105,564 | 51,836 | -53,728 | 0.98 | 0.71 | -0.27 | sell |
| Granahan Investment Management, LLC | 0 | 50,508 | +50,508 | 0.00 | 0.19 | +0.19 | buy |
| Verition Fund Management LLC | 30,975 | 47,528 | +16,553 | 0.01 | 0.02 | +0.01 | buy |
| RHUMBLINE ADVISERS | 48,540 | 47,095 | -1,445 | 0.00 | 0.00 | +0.00 | sell |
| GILDER GAGNON HOWE & CO LLC | 17,498 | 43,722 | +26,224 | 0.01 | 0.04 | +0.03 | buy |
| AMERIPRISE FINANCIAL INC | 10,493 | 41,016 | +30,523 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 3,600 | 40,926 | +37,326 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 39,480 | 40,280 | +800 | 0.00 | 0.00 | +0.00 | buy |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 0 | 38,495 | +38,495 | 0.00 | 0.01 | +0.01 | buy |
| ALLIANCEBERNSTEIN L.P. | 36,581 | 38,351 | +1,770 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 27,924 | 37,765 | +9,841 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 48,271 | 37,369 | -10,902 | 0.00 | 0.00 | +0.00 | sell |
| LPL Financial LLC | 46,058 | 36,001 | -10,057 | 0.00 | 0.00 | +0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 29,612 | 34,774 | +5,162 | 0.00 | 0.00 | +0.00 | buy |
| Legal Advantage Investments, Inc. | 21,000 | 33,500 | +12,500 | 0.56 | 1.33 | +0.77 | buy |
| Jackson Hole Capital Partners, LLC | 33,000 | 33,000 | 0 | 0.33 | 0.48 | +0.15 | hold |
| GABELLI FUNDS LLC | 34,473 | 31,650 | -2,823 | 0.01 | 0.02 | +0.00 | sell |
| Baird Financial Group, Inc. | 0 | 31,074 | +31,074 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 30,552 | 30,918 | +366 | 0.00 | 0.00 | +0.00 | buy |
| Catalio Capital Management, LP | 137,928 | 30,313 | -107,615 | 1.51 | 0.46 | -1.05 | sell |
| Informed Momentum Co LLC | 0 | 29,692 | +29,692 | 0.00 | 0.28 | +0.28 | buy |
| OSAIC HOLDINGS, INC. | 30,325 | 29,266 | -1,059 | 0.00 | 0.00 | +0.00 | sell |
| Mutual Advisors, LLC | 29,577 | 29,136 | -441 | 0.05 | 0.05 | -0.00 | sell |
| IEQ CAPITAL, LLC | 29,492 | 28,522 | -970 | 0.01 | 0.01 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 26,840 | 28,509 | +1,669 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 47,200 | 28,450 | -18,750 | 0.02 | 0.01 | -0.00 | sell |
| VAN ECK ASSOCIATES CORP | 26,773 | 27,533 | +760 | 0.00 | 0.00 | +0.00 | buy |
| COMMERCE BANK | 28,460 | 26,867 | -1,593 | 0.01 | 0.01 | +0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 4,310 | 25,095 | +20,785 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 67,021 | 25,013 | -42,008 | 0.02 | 0.01 | -0.01 | sell |
| GAMCO INVESTORS, INC. ET AL | 24,207 | 24,658 | +451 | 0.01 | 0.02 | +0.01 | buy |
| Gotham Asset Management, LLC | 32,395 | 23,282 | -9,113 | 0.01 | 0.01 | -0.00 | sell |
| Blackstone Inc. | 0 | 23,036 | +23,036 | 0.00 | 0.01 | +0.01 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 17,955 | 23,002 | +5,047 | 0.00 | 0.00 | +0.00 | buy |
| Banque Transatlantique SA | 0 | 23,000 | +23,000 | 0.00 | 0.05 | +0.05 | buy |
| PROFUND ADVISORS LLC | 9,442 | 22,776 | +13,334 | 0.02 | 0.06 | +0.04 | buy |
| NWF Advisory Services Inc. | 20,506 | 22,070 | +1,564 | 0.13 | 0.21 | +0.08 | buy |
| Mariner, LLC | 15,503 | 21,759 | +6,256 | 0.00 | 0.00 | +0.00 | buy |