| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| GEODE CAPITAL MANAGEMENT, LLC | 481,128 | 524,869 | +43,741 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 55,051 | 92,939 | +37,888 | 0.00 | 0.00 | +0.00 | buy |
| MACKENZIE FINANCIAL CORP | 187,559 | 209,031 | +21,472 | 0.00 | 0.00 | +0.00 | buy |
| EP Wealth Advisors, LLC | 0 | 16,500 | +16,500 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 86,447 | 100,924 | +14,477 | 0.00 | 0.00 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 49,200 | 56,000 | +6,800 | 0.00 | 0.00 | -0.00 | buy |
| DLK Investment Management, LLC | 28,955 | 29,825 | +870 | 0.01 | 0.01 | -0.00 | buy |
| FMR LLC | 4,289 | 5,056 | +767 | 0.00 | 0.00 | -0.00 | buy |
| Banque Transatlantique SA | 0 | 400 | +400 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,763,620 | 1,763,620 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 12 | 12 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Texas Yale Capital Corp. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DAFNA Capital Management LLC | 125,000 | 125,000 | 0 | 0.03 | 0.03 | -0.01 | hold |
| NewEdge Advisors, LLC | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Alphabet Inc. | 889,979 | 889,979 | 0 | 0.05 | 0.04 | -0.01 | hold |
| Murchinson Ltd. | 873,910 | 873,910 | 0 | 0.40 | 0.09 | -0.32 | hold |
| MONIMUS CAPITAL MANAGEMENT, LP | 310,908 | 310,908 | 0 | 0.30 | 0.19 | -0.11 | hold |
| CoreCap Advisors, LLC | 50 | 50 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Atlas Venture Life Science Advisors, LLC | 305,255 | 305,255 | 0 | 0.04 | 0.04 | +0.00 | hold |
| ADAR1 Capital Management, LLC | 801,277 | 801,277 | 0 | 0.17 | 0.11 | -0.06 | hold |
| Three Seasons Wealth, LLC | 30,000 | 30,000 | 0 | 0.02 | 0.01 | -0.00 | hold |
| CULLEN/FROST BANKERS, INC. | 2,000 | 2,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PFIZER INC | 2,362,348 | 2,362,348 | 0 | 0.09 | 0.34 | +0.25 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 28,565 | 28,565 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 148,911 | 148,911 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 5,110 | 5,098 | -12 | 0.00 | 0.00 | -0.00 | sell |
| Federation des caisses Desjardins du Quebec | 30 | 0 | -30 | 0.00 | 0.00 | -0.00 | sell |
| RICHARDS, MERRILL & PETERSON, INC. | 150 | 0 | -150 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 213 | 60 | -153 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 485,352 | 482,082 | -3,270 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 5,151 | 151 | -5,000 | 0.00 | 0.00 | -0.00 | sell |
| NATIONAL BANK OF CANADA /FI/ | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 10,003 | 0 | -10,003 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 14,692 | 0 | -14,692 | 0.00 | 0.00 | -0.00 | sell |
| PFG Investments, LLC | 24,534 | 0 | -24,534 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 184,800 | 154,800 | -30,000 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 30,138 | 0 | -30,138 | 0.00 | 0.00 | -0.00 | sell |
| Anson Funds Management LP | 3,839,886 | 3,798,932 | -40,954 | 0.49 | 0.65 | +0.16 | sell |
| Virtu Financial LLC | 46,046 | 0 | -46,046 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 61,624 | 0 | -61,624 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 1,105,591 | 970,907 | -134,684 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 1,039,922 | 871,212 | -168,710 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 172,872 | 0 | -172,872 | 0.00 | 0.00 | -0.00 | sell |