| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 27,525,640 | 27,525,640 | 0 | 1.00 | 0.55 | -0.45 | hold |
| Capital World Investors | 13,361,096 | 13,361,096 | 0 | 0.01 | 0.01 | -0.00 | hold |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 7,876,629 | +7,876,629 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 5,175,142 | 5,810,985 | +635,843 | 0.04 | 0.03 | -0.01 | buy |
| TWO SIGMA ADVISERS, LP | 4,799,900 | 4,878,000 | +78,100 | 0.05 | 0.03 | -0.02 | buy |
| GOLDMAN SACHS GROUP INC | 250,217 | 4,344,485 | +4,094,268 | 0.00 | 0.00 | +0.00 | buy |
| ArrowMark Colorado Holdings LLC | 4,105,095 | 4,105,095 | 0 | 0.38 | 0.31 | -0.07 | hold |
| BlackRock, Inc. | 3,641,779 | 3,865,896 | +224,117 | 0.00 | 0.00 | -0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 1,726,941 | 3,771,999 | +2,045,058 | 0.06 | 0.09 | +0.03 | buy |
| MORGAN STANLEY | 2,792,142 | 3,001,850 | +209,708 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 2,418,304 | 2,632,872 | +214,568 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 3,360,729 | 2,389,229 | -971,500 | 0.02 | 0.01 | -0.01 | sell |
| UBS Group AG | 2,489,200 | 1,939,409 | -549,791 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 1,008,615 | 1,834,508 | +825,893 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 730,122 | 1,796,010 | +1,065,888 | 0.02 | 0.03 | +0.01 | buy |
| Guardian Partners Inc. | 1,786,414 | 1,786,414 | 0 | 0.90 | 0.47 | -0.43 | hold |
| MILLENNIUM MANAGEMENT LLC | 2,429,736 | 1,773,539 | -656,197 | 0.01 | 0.00 | -0.01 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,418,533 | 1,524,563 | +106,030 | 0.01 | 0.01 | -0.00 | buy |
| JANE STREET GROUP, LLC | 397,144 | 1,397,088 | +999,944 | 0.00 | 0.01 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 976,507 | +976,507 | 0.00 | 0.01 | +0.01 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 257,735 | 695,796 | +438,061 | 0.00 | 0.01 | +0.00 | buy |
| STATE STREET CORP | 671,017 | 694,114 | +23,097 | 0.00 | 0.00 | -0.00 | buy |
| HRT FINANCIAL LP | 436,575 | 548,431 | +111,856 | 0.01 | 0.01 | -0.00 | buy |
| Intellectus Partners, LLC | 543,133 | 523,383 | -19,750 | 0.53 | 0.35 | -0.18 | sell |
| STATE OF MICHIGAN RETIREMENT SYSTEM | 400,000 | 400,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| ROYAL BANK OF CANADA | 503,964 | 373,856 | -130,108 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 0 | 363,251 | +363,251 | 0.00 | 0.03 | +0.03 | buy |
| OSAIC HOLDINGS, INC. | 343,075 | 347,321 | +4,246 | 0.00 | 0.00 | -0.00 | buy |
| SOFTBANK GROUP CORP. | 0 | 345,161 | +345,161 | 0.00 | 0.01 | +0.01 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 340,267 | 340,267 | 0 | 0.01 | 0.00 | -0.00 | hold |
| LAZARD ASSET MANAGEMENT LLC | 652,096 | 328,717 | -323,379 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 329,223 | 313,467 | -15,756 | 0.00 | 0.00 | -0.00 | sell |
| Voleon Capital Management LP | 11,200 | 265,325 | +254,125 | 0.00 | 0.02 | +0.02 | buy |
| CITIZENS FINANCIAL GROUP INC/RI | 261,890 | 261,890 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Graham Capital Management, L.P. | 26,113 | 257,838 | +231,725 | 0.00 | 0.03 | +0.03 | buy |
| Walleye Capital LLC | 0 | 249,050 | +249,050 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 38,418 | 247,050 | +208,632 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 245,963 | 245,963 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 146,777 | 211,281 | +64,504 | 0.00 | 0.00 | -0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 736,945 | 209,925 | -527,020 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 218,028 | 208,072 | -9,956 | 0.00 | 0.00 | -0.00 | sell |
| Quadrature Capital Ltd | 0 | 205,095 | +205,095 | 0.00 | 0.01 | +0.01 | buy |
| Headlands Technologies LLC | 119,591 | 188,787 | +69,196 | 0.05 | 0.05 | +0.01 | buy |
| Virtu Financial LLC | 0 | 181,031 | +181,031 | 0.00 | 0.02 | +0.02 | buy |
| NORGES BANK | 0 | 176,386 | +176,386 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 65,508 | 146,359 | +80,851 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 159,415 | 141,885 | -17,530 | 0.01 | 0.01 | -0.00 | sell |
| Squarepoint Ops LLC | 102,471 | 133,069 | +30,598 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 121,023 | 128,999 | +7,976 | 0.02 | 0.01 | -0.01 | buy |
| Qube Research & Technologies Ltd | 0 | 122,592 | +122,592 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 24,617 | 117,031 | +92,414 | 0.00 | 0.00 | +0.00 | buy |
| ArchPoint Investors | 115,055 | 115,055 | 0 | 0.16 | 0.09 | -0.07 | hold |
| AMERICAN CENTURY COMPANIES INC | 113,760 | 113,760 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ExodusPoint Capital Management, LP | 0 | 113,068 | +113,068 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 0 | 109,000 | +109,000 | 0.00 | 0.03 | +0.03 | buy |
| PIER 88 INVESTMENT PARTNERS LLC | 108,870 | 105,730 | -3,140 | 0.10 | 0.08 | -0.02 | sell |
| POLEN CAPITAL MANAGEMENT LLC | 269,248 | 102,508 | -166,740 | 0.00 | 0.00 | -0.00 | sell |
| DekaBank Deutsche Girozentrale | 87,000 | 87,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STIFEL FINANCIAL CORP | 102,778 | 85,169 | -17,609 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 675,600 | 81,271 | -594,329 | 0.05 | 0.00 | -0.05 | sell |
| HighTower Advisors, LLC | 30,213 | 79,963 | +49,750 | 0.00 | 0.00 | +0.00 | buy |
| Handelsbanken Fonder AB | 0 | 79,300 | +79,300 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 76,483 | 77,776 | +1,293 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 130,664 | 77,614 | -53,050 | 0.00 | 0.00 | -0.00 | sell |
| Virtus Investment Advisers, LLC | 36,123 | 73,488 | +37,365 | 0.05 | 0.07 | +0.02 | buy |
| TWO SIGMA SECURITIES, LLC | 13,045 | 68,284 | +55,239 | 0.01 | 0.03 | +0.02 | buy |
| Erste Asset Management GmbH | 62,000 | 62,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Resolute Advisors LLC | 57,526 | 57,526 | 0 | 0.07 | 0.06 | -0.01 | hold |
| Invesco Ltd. | 42,689 | 54,603 | +11,914 | 0.00 | 0.00 | -0.00 | buy |
| Cerity Partners LLC | 53,057 | 52,057 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 52,381 | 48,777 | -3,604 | 0.02 | 0.01 | -0.01 | sell |
| Tradition Wealth Management, LLC | 36,138 | 47,110 | +10,972 | 0.01 | 0.01 | -0.00 | buy |
| XML Financial, LLC | 42,025 | 42,025 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Creative Planning | 47,733 | 41,844 | -5,889 | 0.00 | 0.00 | -0.00 | sell |
| Federation des caisses Desjardins du Quebec | 43,656 | 39,862 | -3,794 | 0.00 | 0.00 | -0.00 | sell |
| SIGNATURE ESTATE & INVESTMENT ADVISORS LLC | 38,668 | 35,668 | -3,000 | 0.00 | 0.00 | -0.00 | sell |
| nVerses Capital, LLC | 0 | 35,446 | +35,446 | 0.00 | 0.27 | +0.27 | buy |
| BARCLAYS PLC | 30,898 | 33,547 | +2,649 | 0.00 | 0.00 | -0.00 | buy |
| Advisory Services Network, LLC | 26,278 | 29,664 | +3,386 | 0.00 | 0.00 | -0.00 | buy |
| BRANDYWINE MANAGERS, LLC | 28,488 | 28,488 | 0 | 0.14 | 0.05 | -0.09 | hold |
| Green Alpha Advisors, LLC | 22,775 | 27,592 | +4,817 | 0.11 | 0.09 | -0.02 | buy |
| HBK Sorce Advisory LLC | 0 | 24,956 | +24,956 | 0.00 | 0.00 | +0.00 | buy |
| OneDigital Investment Advisors LLC | 10,250 | 24,000 | +13,750 | 0.00 | 0.00 | +0.00 | buy |
| Stratos Wealth Advisors, LLC | 19,000 | 23,000 | +4,000 | 0.00 | 0.00 | -0.00 | buy |
| TD Waterhouse Canada Inc. | 24,538 | 22,412 | -2,126 | 0.00 | 0.00 | -0.00 | sell |
| CIBC WORLD MARKET INC. | 16,365 | 20,706 | +4,341 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 5,174 | 20,075 | +14,901 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 19,580 | +19,580 | 0.00 | 0.00 | +0.00 | buy |
| Scientech Research LLC | 0 | 18,988 | +18,988 | 0.00 | 0.04 | +0.04 | buy |
| HB Wealth Management, LLC | 28,981 | 18,981 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Ballentine Partners, LLC | 25,011 | 18,603 | -6,408 | 0.00 | 0.00 | -0.00 | sell |
| Farther Finance Advisors, LLC | 16,645 | 16,645 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SCOTIA CAPITAL INC. | 26,666 | 15,943 | -10,723 | 0.00 | 0.00 | -0.00 | sell |
| OXFORD ASSET MANAGEMENT LLP | 0 | 14,875 | +14,875 | 0.00 | 0.02 | +0.02 | buy |
| Mirae Asset Global Investments Co., Ltd. | 11,553 | 14,546 | +2,993 | 0.00 | 0.00 | -0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 15,815 | 14,495 | -1,320 | 0.00 | 0.00 | -0.00 | sell |
| Magnetar Financial LLC | 0 | 14,264 | +14,264 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 10,646 | 13,240 | +2,594 | 0.00 | 0.00 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 12,702 | 12,878 | +176 | 0.00 | 0.00 | -0.00 | buy |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 11,800 | 12,700 | +900 | 0.00 | 0.00 | -0.00 | buy |