| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 1,040,054 | +1,040,054 | 0.00 | 0.02 | +0.02 | buy |
| VR Adviser, LLC | 0 | 1,009,500 | +1,009,500 | 0.00 | 0.43 | +0.43 | buy |
| Lynx1 Capital Management LP | 677,915 | 1,538,296 | +860,381 | 1.10 | 2.75 | +1.65 | buy |
| Affinity Asset Advisors, LLC | 0 | 706,904 | +706,904 | 0.00 | 0.47 | +0.47 | buy |
| ADAR1 Capital Management, LLC | 0 | 540,054 | +540,054 | 0.00 | 0.37 | +0.37 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 450,045 | +450,045 | 0.00 | 0.04 | +0.04 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 228,400 | +228,400 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 40,647 | 267,755 | +227,108 | 0.00 | 0.00 | +0.00 | buy |
| NEA Management Company, LLC | 1,090,793 | 1,297,893 | +207,100 | 0.45 | 0.84 | +0.39 | buy |
| TWO SIGMA INVESTMENTS, LP | 78,984 | 165,472 | +86,488 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 68,500 | +68,500 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 74,900 | 136,227 | +61,327 | 0.00 | 0.00 | +0.00 | buy |
| Nantahala Capital Management, LLC | 600,000 | 660,036 | +60,036 | 0.29 | 0.47 | +0.18 | buy |
| Trexquant Investment LP | 0 | 56,208 | +56,208 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 42,000 | +42,000 | 0.00 | 0.01 | +0.01 | buy |
| Mariner, LLC | 0 | 25,819 | +25,819 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 23,031 | 42,838 | +19,807 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 19,125 | +19,125 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 19,772 | 34,343 | +14,571 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 0 | 12,777 | +12,777 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 162,760 | 173,643 | +10,883 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 10,790 | +10,790 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 9,772 | +9,772 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 27,597 | 35,978 | +8,381 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 33,790 | 41,825 | +8,035 | 0.00 | 0.00 | +0.00 | buy |
| GUGGENHEIM CAPITAL LLC | 10,439 | 14,097 | +3,658 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 57,067 | 60,472 | +3,405 | 0.01 | 0.01 | -0.00 | buy |
| Bank of New York Mellon Corp | 18,855 | 21,730 | +2,875 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 457,399 | 460,006 | +2,607 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 55,640 | 57,702 | +2,062 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 37,857 | 38,900 | +1,043 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 1,487 | 2,354 | +867 | 0.00 | 0.00 | +0.00 | buy |
| Versant Capital Management, Inc | 0 | 691 | +691 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 102 | 737 | +635 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 5 | 606 | +601 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 379 | +379 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 1 | 291 | +290 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,391 | 1,644 | +253 | 0.00 | 0.00 | +0.00 | buy |
| Advisory Services Network, LLC | 0 | 245 | +245 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 1,930 | 2,115 | +185 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 91 | 225 | +134 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 99 | +99 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 86 | +86 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 3,146 | 3,214 | +68 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 6 | 72 | +66 | 0.00 | 0.00 | +0.00 | buy |
| Root Financial Partners, LLC | 0 | 63 | +63 | 0.00 | 0.00 | +0.00 | buy |
| Wealth Preservation Advisors, LLC | 0 | 44 | +44 | 0.00 | 0.00 | +0.00 | buy |
| Bare Financial Services, Inc | 0 | 44 | +44 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 40 | +40 | 0.00 | 0.00 | +0.00 | buy |
| Fortitude Family Office, LLC | 0 | 39 | +39 | 0.00 | 0.00 | +0.00 | buy |
| SJS Investment Consulting Inc. | 0 | 22 | +22 | 0.00 | 0.00 | +0.00 | buy |
| Sunbelt Securities, Inc. | 1 | 17 | +16 | 0.00 | 0.00 | +0.00 | buy |
| FIFTH THIRD BANCORP | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| TD Waterhouse Canada Inc. | 800 | 808 | +8 | 0.00 | 0.00 | -0.00 | buy |
| IFP Advisors, Inc | 40 | 45 | +5 | 0.00 | 0.00 | +0.00 | buy |
| JPL Wealth Management, LLC | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| DUNCKER STREETT & CO INC | 437 | 437 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ameritas Investment Partners, Inc. | 598 | 598 | 0 | 0.00 | 0.00 | +0.00 | hold |
| North Star Investment Management Corp. | 1,800 | 1,800 | 0 | 0.00 | 0.00 | +0.00 | hold |
| 72 Investment Holdings, LLC | 276,831 | 276,831 | 0 | 4.38 | 6.32 | +1.93 | hold |
| TCG Crossover Management, LLC | 416,301 | 416,301 | 0 | 0.11 | 0.13 | +0.02 | hold |
| SBI Securities Co., Ltd. | 1 | 1 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Atlas Venture Life Science Advisors, LLC | 1,137,149 | 1,137,149 | 0 | 1.05 | 1.63 | +0.58 | hold |
| Siren, L.L.C. | 347,718 | 347,718 | 0 | 0.08 | 0.11 | +0.03 | hold |
| Police & Firemen's Retirement System of New Jersey | 1,373 | 1,373 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 526 | 526 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 3,000 | 3,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 2 | 0 | -2 | 0.00 | 0.00 | -0.00 | sell |
| Optiver Holding B.V. | 116 | 60 | -56 | 0.00 | 0.00 | +0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 110 | 0 | -110 | 0.00 | 0.00 | -0.00 | sell |
| AMALGAMATED BANK | 208 | 0 | -208 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 458 | 220 | -238 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 607 | 308 | -299 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 302 | 0 | -302 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 10,250 | 9,850 | -400 | 0.00 | 0.00 | +0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 408 | 0 | -408 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 51,950 | 50,541 | -1,409 | 0.00 | 0.00 | +0.00 | sell |
| Steward Partners Investment Advisory, LLC | 1,500 | 0 | -1,500 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 12,758 | 10,544 | -2,214 | 0.00 | 0.00 | +0.00 | sell |
| EMERALD MUTUAL FUND ADVISERS TRUST | 65,548 | 62,855 | -2,693 | 0.03 | 0.03 | +0.01 | sell |
| F/m Investments LLC | 65,548 | 62,855 | -2,693 | 0.02 | 0.05 | +0.03 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 16,329 | 13,394 | -2,935 | 0.00 | 0.00 | +0.00 | sell |
| Engineers Gate Manager LP | 26,885 | 23,702 | -3,183 | 0.00 | 0.00 | +0.00 | sell |
| GROUP ONE TRADING LLC | 4,000 | 0 | -4,000 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 146,221 | 140,341 | -5,880 | 0.00 | 0.00 | +0.00 | sell |
| Quadrature Capital Ltd | 27,064 | 20,356 | -6,708 | 0.00 | 0.00 | +0.00 | sell |
| AlphaQuest LLC | 7,703 | 0 | -7,703 | 0.00 | 0.00 | -0.00 | sell |
| ALGERT GLOBAL LLC | 27,065 | 19,185 | -7,880 | 0.00 | 0.00 | -0.00 | sell |
| Jain Global LLC | 10,574 | 0 | -10,574 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 10,590 | 0 | -10,590 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 11,237 | 0 | -11,237 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 58,329 | 30,914 | -27,415 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 28,247 | 0 | -28,247 | 0.01 | 0.00 | -0.01 | sell |
| Graham Capital Management, L.P. | 40,766 | 0 | -40,766 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 161,092 | 63,606 | -97,486 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 288,457 | 115,704 | -172,753 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 196,827 | 0 | -196,827 | 0.00 | 0.00 | -0.00 | sell |