| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Mirae Asset Global Investments Co., Ltd. | 4,603 | 2,132,201 | +2,127,598 | 0.00 | 0.00 | +0.00 | buy |
| Clearbridge Investments, LLC | 1,862,842 | 3,279,567 | +1,416,725 | 0.04 | 0.10 | +0.06 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 1,762,954 | 2,884,810 | +1,121,856 | 0.03 | 0.06 | +0.03 | buy |
| FMR LLC | 5,475,505 | 6,378,128 | +902,623 | 0.01 | 0.01 | +0.01 | buy |
| JENNISON ASSOCIATES LLC | 0 | 712,300 | +712,300 | 0.00 | 0.02 | +0.02 | buy |
| RTW INVESTMENTS, LP | 2,509,119 | 3,136,680 | +627,561 | 0.99 | 1.73 | +0.74 | buy |
| Allianz Asset Management GmbH | 1,505,866 | 1,884,411 | +378,545 | 0.06 | 0.10 | +0.04 | buy |
| Frazier Life Sciences Management, L.P. | 0 | 350,000 | +350,000 | 0.00 | 0.58 | +0.58 | buy |
| XY Capital Ltd | 0 | 305,397 | +305,397 | 0.00 | 7.27 | +7.27 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 23,508 | 296,278 | +272,770 | 0.00 | 0.03 | +0.03 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 0 | 262,500 | +262,500 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 160,378 | 401,082 | +240,704 | 0.00 | 0.01 | +0.01 | buy |
| MY.Alpha Management HK Advisors Ltd | 0 | 239,146 | +239,146 | 0.00 | 4.30 | +4.30 | buy |
| D. E. Shaw & Co., Inc. | 73,412 | 307,955 | +234,543 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 180,052 | 382,469 | +202,417 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 62,114 | 232,503 | +170,389 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 841,735 | 1,009,020 | +167,285 | 0.10 | 0.16 | +0.06 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 166,063 | +166,063 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 37,278 | 178,714 | +141,436 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 49,365 | 162,698 | +113,333 | 0.00 | 0.00 | +0.00 | buy |
| OLD MISSION CAPITAL LLC | 0 | 107,997 | +107,997 | 0.00 | 0.08 | +0.08 | buy |
| WELLS FARGO & COMPANY/MN | 40,954 | 138,830 | +97,876 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 39,420 | 125,967 | +86,547 | 0.00 | 0.00 | +0.00 | buy |
| Penserra Capital Management LLC | 0 | 67,159 | +67,159 | 0.00 | 0.04 | +0.04 | buy |
| NEOS Investment Management LLC | 0 | 64,262 | +64,262 | 0.00 | 0.04 | +0.04 | buy |
| TEMA ETFS LLC | 0 | 64,262 | +64,262 | 0.00 | 0.69 | +0.69 | buy |
| NINE MASTS CAPITAL Ltd | 0 | 50,500 | +50,500 | 0.00 | 1.40 | +1.40 | buy |
| LMR Partners LLP | 19,840 | 62,479 | +42,639 | 0.01 | 0.05 | +0.04 | buy |
| MPM BioImpact LLC | 800,000 | 833,659 | +33,659 | 2.97 | 5.18 | +2.20 | buy |
| Man Group plc | 0 | 31,170 | +31,170 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 29,693 | +29,693 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 29,520 | +29,520 | 0.00 | 0.04 | +0.04 | buy |
| MML INVESTORS SERVICES, LLC | 0 | 27,807 | +27,807 | 0.00 | 0.00 | +0.00 | buy |
| STEMPOINT CAPITAL LP | 0 | 26,421 | +26,421 | 0.00 | 0.30 | +0.30 | buy |
| TWO SIGMA INVESTMENTS, LP | 29,757 | 55,843 | +26,086 | 0.00 | 0.00 | +0.00 | buy |
| DCF Advisers, LLC | 64,750 | 90,000 | +25,250 | 0.86 | 1.75 | +0.89 | buy |
| Tower Research Capital LLC (TRC) | 366 | 24,863 | +24,497 | 0.00 | 0.03 | +0.03 | buy |
| LPL Financial LLC | 0 | 24,309 | +24,309 | 0.00 | 0.00 | +0.00 | buy |
| Orion Porfolio Solutions, LLC | 11,956 | 36,259 | +24,303 | 0.00 | 0.01 | +0.01 | buy |
| Legacy Wealth Asset Management, LLC | 0 | 22,285 | +22,285 | 0.00 | 0.22 | +0.22 | buy |
| Walleye Capital LLC | 438 | 22,276 | +21,838 | 0.00 | 0.01 | +0.01 | buy |
| Cubist Systematic Strategies, LLC | 72,619 | 93,645 | +21,026 | 0.03 | 0.04 | +0.01 | buy |
| TOWNSQUARE CAPITAL LLC | 9,290 | 29,636 | +20,346 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA ADVISERS, LP | 18,200 | 38,200 | +20,000 | 0.00 | 0.00 | +0.00 | buy |
| MISSION WEALTH MANAGEMENT, LP | 0 | 20,000 | +20,000 | 0.00 | 0.02 | +0.02 | buy |
| Nan Fung Group Holdings Ltd | 235,000 | 253,675 | +18,675 | 5.26 | 7.48 | +2.21 | buy |
| OPPENHEIMER ASSET MANAGEMENT INC. | 0 | 16,689 | +16,689 | 0.00 | 0.01 | +0.01 | buy |
| Virtus Investment Advisers, LLC | 0 | 13,435 | +13,435 | 0.00 | 0.13 | +0.13 | buy |
| US BANCORP \DE\ | 5,865 | 18,365 | +12,500 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 11,617 | +11,617 | 0.00 | 0.00 | +0.00 | buy |
| GTS SECURITIES LLC | 0 | 10,880 | +10,880 | 0.00 | 0.02 | +0.02 | buy |
| Marks Group Wealth Management, Inc | 0 | 10,331 | +10,331 | 0.00 | 0.04 | +0.04 | buy |
| Invesco Ltd. | 44,340 | 54,544 | +10,204 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 4,381 | 13,771 | +9,390 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 9,359 | +9,359 | 0.00 | 0.02 | +0.02 | buy |
| MACKENZIE FINANCIAL CORP | 0 | 8,402 | +8,402 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 0 | 8,230 | +8,230 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 0 | 8,138 | +8,138 | 0.00 | 0.00 | +0.00 | buy |
| PEAK6 LLC | 0 | 7,500 | +7,500 | 0.00 | 0.01 | +0.01 | buy |
| Bellevue Group AG | 13,000 | 20,000 | +7,000 | 0.01 | 0.02 | +0.01 | buy |
| Atria Investments, Inc | 0 | 6,865 | +6,865 | 0.00 | 0.00 | +0.00 | buy |
| TRUIST FINANCIAL CORP | 0 | 6,607 | +6,607 | 0.00 | 0.00 | +0.00 | buy |
| ABC ARBITRAGE SA | 0 | 6,239 | +6,239 | 0.00 | 0.04 | +0.04 | buy |
| AVANTAX ADVISORY SERVICES, INC. | 0 | 6,234 | +6,234 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 18,840 | 25,000 | +6,160 | 0.00 | 0.00 | +0.00 | buy |
| RWC Asset Management LLP | 0 | 6,144 | +6,144 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF MONTREAL /CAN/ | 16,893 | 22,991 | +6,098 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 0 | 5,868 | +5,868 | 0.00 | 0.01 | +0.01 | buy |
| Palumbo Wealth Management LLC | 0 | 5,612 | +5,612 | 0.00 | 0.07 | +0.07 | buy |
| Hennion & Walsh Asset Management, Inc. | 183,317 | 187,747 | +4,430 | 0.22 | 0.30 | +0.08 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 18,480 | 22,098 | +3,618 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 55,520 | 58,492 | +2,972 | 0.00 | 0.00 | +0.00 | buy |
| Advisors Preferred, LLC | 0 | 2,948 | +2,948 | 0.00 | 0.01 | +0.01 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 2,081 | +2,081 | 0.00 | 0.06 | +0.06 | buy |
| China Universal Asset Management Co., Ltd. | 11,061 | 12,544 | +1,483 | 0.03 | 0.04 | +0.02 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 1,305 | +1,305 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 3,702 | 4,702 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Kingsview Wealth Management, LLC | 8,794 | 9,323 | +529 | 0.00 | 0.01 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,095 | 1,336 | +241 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 19,502 | 19,693 | +191 | 0.00 | 0.00 | +0.00 | buy |
| WHITTIER TRUST CO OF NEVADA INC | 80 | 256 | +176 | 0.00 | 0.00 | +0.00 | buy |
| PRIVATE TRUST CO NA | 13 | 177 | +164 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Private Wealth Group LLC | 0 | 155 | +155 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 98 | 151 | +53 | 0.00 | 0.00 | +0.00 | buy |
| BARTLETT & CO. WEALTH MANAGEMENT LLC | 0 | 35 | +35 | 0.00 | 0.00 | +0.00 | buy |
| Marshall & Sterling Wealth Advisors Inc. | 0 | 34 | +34 | 0.00 | 0.00 | +0.00 | buy |
| CREATIVE FINANCIAL DESIGNS INC /ADV | 0 | 29 | +29 | 0.00 | 0.00 | +0.00 | buy |
| Cornerstone Planning Group LLC | 0 | 22 | +22 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 15,555 | 15,572 | +17 | 0.00 | 0.00 | +0.00 | buy |
| Retirement Wealth Solutions LLC | 38 | 53 | +15 | 0.00 | 0.00 | +0.00 | buy |
| Farther Finance Advisors, LLC | 181 | 195 | +14 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| HUNTINGTON NATIONAL BANK | 0 | 7 | +7 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 91,504 | 91,504 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRINCIPAL SECURITIES, INC. | 290 | 290 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 1,295,040 | 1,295,040 | 0 | 0.45 | 0.78 | +0.33 | hold |
| Robeco Institutional Asset Management B.V. | 52,035 | 52,035 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Jasper Ridge Partners, L.P. | 8,024 | 8,024 | 0 | 0.01 | 0.01 | +0.00 | hold |
| DekaBank Deutsche Girozentrale | 36,648 | 36,648 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NJ State Employees Deferred Compensation Plan | 11,300 | 11,300 | 0 | 0.04 | 0.05 | +0.02 | hold |