| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 0 | 1,084,539 | +1,084,539 | 0.00 | 0.09 | +0.09 | buy |
| Sio Capital Management, LLC | 0 | 1,054,651 | +1,054,651 | 0.00 | 2.18 | +2.18 | buy |
| Artisan Partners Limited Partnership | 0 | 918,529 | +918,529 | 0.00 | 0.01 | +0.01 | buy |
| Ikarian Capital, LLC | 0 | 897,862 | +897,862 | 0.00 | 1.88 | +1.88 | buy |
| Point72 Asset Management, L.P. | 5,215 | 848,454 | +843,239 | 0.00 | 0.02 | +0.02 | buy |
| JPMORGAN CHASE & CO | 1,086,327 | 1,807,017 | +720,690 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,212,105 | 1,915,465 | +703,360 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,104,716 | 1,715,083 | +610,367 | 0.01 | 0.01 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 93,329 | 581,829 | +488,500 | 0.11 | 0.79 | +0.67 | buy |
| Walleye Capital LLC | 23,776 | 434,460 | +410,684 | 0.00 | 0.03 | +0.03 | buy |
| Aberdeen Group plc | 0 | 363,161 | +363,161 | 0.00 | 0.01 | +0.01 | buy |
| Hudson Bay Capital Management LP | 528,242 | 849,873 | +321,631 | 0.03 | 0.04 | +0.01 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 260,371 | +260,371 | 0.00 | 0.06 | +0.06 | buy |
| ExodusPoint Capital Management, LP | 0 | 246,833 | +246,833 | 0.00 | 0.02 | +0.02 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 15,200 | 201,185 | +185,985 | 0.00 | 0.02 | +0.02 | buy |
| GROUP ONE TRADING LLC | 0 | 179,262 | +179,262 | 0.00 | 0.04 | +0.04 | buy |
| Stonepine Capital Management, LLC | 0 | 164,106 | +164,106 | 0.00 | 0.97 | +0.97 | buy |
| Woodline Partners LP | 0 | 135,036 | +135,036 | 0.00 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,134,276 | 1,252,655 | +118,379 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 4,273 | 116,627 | +112,354 | 0.00 | 0.02 | +0.02 | buy |
| ALPS ADVISORS INC | 0 | 111,360 | +111,360 | 0.00 | 0.01 | +0.01 | buy |
| Squarepoint Ops LLC | 103,700 | 214,263 | +110,563 | 0.00 | 0.00 | +0.00 | buy |
| DAFNA Capital Management LLC | 0 | 100,000 | +100,000 | 0.00 | 0.19 | +0.19 | buy |
| Allianz Asset Management GmbH | 72,356 | 171,949 | +99,593 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 52,794 | 145,873 | +93,079 | 0.00 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 88,608 | 178,138 | +89,530 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 16,375,806 | 16,462,717 | +86,911 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 114,418 | 184,317 | +69,899 | 0.00 | 0.00 | +0.00 | buy |
| Quinn Opportunity Partners LLC | 0 | 65,976 | +65,976 | 0.00 | 0.03 | +0.03 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,182,300 | 1,237,600 | +55,300 | 0.01 | 0.01 | +0.00 | buy |
| Tejara Capital Ltd | 0 | 51,967 | +51,967 | 0.00 | 0.25 | +0.25 | buy |
| NORTHERN TRUST CORP | 878,924 | 930,454 | +51,530 | 0.00 | 0.00 | -0.00 | buy |
| State of Alaska, Department of Revenue | 152,242 | 202,441 | +50,199 | 0.01 | 0.02 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 49,651 | +49,651 | 0.00 | 0.07 | +0.07 | buy |
| Tower Research Capital LLC (TRC) | 15,013 | 61,391 | +46,378 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 35,915 | 81,250 | +45,335 | 0.01 | 0.02 | +0.01 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 140,371 | 181,325 | +40,954 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 24,606 | 64,906 | +40,300 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 194,208 | 229,294 | +35,086 | 0.01 | 0.01 | -0.00 | buy |
| HRT FINANCIAL LP | 49,022 | 84,049 | +35,027 | 0.00 | 0.00 | +0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 178 | 34,380 | +34,202 | 0.00 | 0.10 | +0.10 | buy |
| Amundi | 14,373 | 46,614 | +32,241 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 42,800 | 74,800 | +32,000 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 26,433 | 56,784 | +30,351 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 189,219 | 216,734 | +27,515 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 26,309 | +26,309 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 24,085 | +24,085 | 0.00 | 0.01 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 206,889 | 230,724 | +23,835 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 23,557 | +23,557 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 23,406 | +23,406 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 11,448 | 32,432 | +20,984 | 0.01 | 0.02 | +0.01 | buy |
| Brevan Howard Capital Management LP | 0 | 20,633 | +20,633 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 17,240 | +17,240 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 431,411 | 447,313 | +15,902 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 0 | 14,188 | +14,188 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 12,836 | +12,836 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 130,347 | 143,077 | +12,730 | 0.00 | 0.00 | +0.00 | buy |
| FIRST TRUST ADVISORS LP | 0 | 12,656 | +12,656 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 12,490 | +12,490 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 25,522 | 37,008 | +11,486 | 0.00 | 0.00 | +0.00 | buy |
| Nebula Research & Development LLC | 0 | 11,445 | +11,445 | 0.00 | 0.01 | +0.01 | buy |
| SYON CAPITAL LLC | 0 | 10,534 | +10,534 | 0.00 | 0.01 | +0.01 | buy |
| CIBC Asset Management Inc | 0 | 10,132 | +10,132 | 0.00 | 0.00 | +0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 25,770 | 35,081 | +9,311 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,188,774 | 2,196,601 | +7,827 | 0.00 | 0.00 | -0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 81,269 | 88,776 | +7,507 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 189,670 | 196,780 | +7,110 | 0.00 | 0.00 | -0.00 | buy |
| ProShare Advisors LLC | 26,796 | 33,563 | +6,767 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 1,234 | 7,116 | +5,882 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 5,690 | +5,690 | 0.00 | 0.01 | +0.01 | buy |
| KBC Group NV | 3,793 | 8,970 | +5,177 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 50,735 | 55,493 | +4,758 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 15,820 | 20,503 | +4,683 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 25,231 | 29,879 | +4,648 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 67,826 | 71,332 | +3,506 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 12,451 | 15,886 | +3,435 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 26,280 | 29,202 | +2,922 | 0.02 | 0.02 | -0.00 | buy |
| Invesco Ltd. | 396,198 | 398,772 | +2,574 | 0.00 | 0.00 | -0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 23,884 | 26,440 | +2,556 | 0.00 | 0.00 | -0.00 | buy |
| Sterling Capital Management LLC | 319 | 2,868 | +2,549 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 268,972 | 271,264 | +2,292 | 0.00 | 0.00 | -0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 6,289 | 8,288 | +1,999 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 235,393 | 236,681 | +1,288 | 0.00 | 0.00 | -0.00 | buy |
| State of Tennessee, Department of Treasury | 38,041 | 39,268 | +1,227 | 0.00 | 0.00 | +0.00 | buy |
| BFSG, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 8,894 | 9,568 | +674 | 0.03 | 0.03 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 410 | 781 | +371 | 0.00 | 0.00 | +0.00 | buy |
| Louisiana State Employees Retirement System | 44,300 | 44,600 | +300 | 0.01 | 0.01 | +0.00 | buy |
| Allworth Financial LP | 3,642 | 3,909 | +267 | 0.00 | 0.00 | +0.00 | buy |
| UMB Bank, n.a. | 42 | 264 | +222 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 27,547 | 27,755 | +208 | 0.00 | 0.00 | +0.00 | buy |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 13,769 | 13,977 | +208 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 19,568 | 19,699 | +131 | 0.00 | 0.00 | -0.00 | buy |
| OREGON PUBLIC EMPLOYEES RETIREMENT FUND | 21,568 | 21,668 | +100 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 170 | 241 | +71 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 80 | 120 | +40 | 0.00 | 0.00 | +0.00 | buy |
| Hexagon Capital Partners LLC | 130 | 163 | +33 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 200 | 219 | +19 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL SECURITIES, INC. | 0 | 16 | +16 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 11 | 27 | +16 | 0.00 | 0.00 | 0.00 | buy |