| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 15,967,656 | 16,330,103 | +362,447 | 0.00 | 0.00 | +0.00 | buy |
| SB INVESTMENT ADVISERS (UK) LTD | 16,684,041 | 13,116,977 | -3,567,064 | 0.72 | 0.79 | +0.07 | sell |
| ARCH Venture Management, LLC | 12,916,663 | 12,916,663 | 0 | 14.98 | 11.95 | -3.03 | hold |
| VANGUARD GROUP INC | 12,799,381 | 12,548,944 | -250,437 | 0.00 | 0.00 | +0.00 | sell |
| STATE STREET CORP | 5,241,293 | 6,229,555 | +988,262 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 3,637,130 | 3,158,416 | -478,714 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 2,689,118 | 2,679,145 | -9,973 | 0.00 | 0.00 | +0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 2,978,871 | 2,536,277 | -442,594 | 0.00 | 0.00 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 2,380,715 | 2,380,715 | 0 | 0.33 | 0.29 | -0.03 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 2,246,222 | 2,328,207 | +81,985 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,521,802 | 1,568,904 | +47,102 | 0.00 | 0.00 | +0.00 | buy |
| Aberdeen Group plc | 1,526,265 | 1,390,577 | -135,688 | 0.01 | 0.01 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 1,368,474 | +1,368,474 | 0.00 | 0.02 | +0.02 | buy |
| Hudson Bay Capital Management LP | 911,882 | 1,325,000 | +413,118 | 0.03 | 0.05 | +0.01 | buy |
| Candriam S.C.A. | 0 | 1,031,663 | +1,031,663 | 0.00 | 0.03 | +0.03 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,396,504 | 1,002,606 | -393,898 | 0.01 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 400,983 | 930,908 | +529,925 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,142,879 | 904,480 | -238,399 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 907,126 | 848,469 | -58,657 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 194,269 | 731,307 | +537,038 | 0.00 | 0.00 | +0.00 | buy |
| Boxer Capital Management, LLC | 0 | 625,000 | +625,000 | 0.00 | 0.82 | +0.82 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,167,100 | 614,464 | -552,636 | 0.01 | 0.01 | -0.00 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 714,561 | 609,726 | -104,835 | 0.00 | 0.00 | -0.00 | sell |
| Clarius Group, LLC | 619,312 | 608,200 | -11,112 | 0.21 | 0.21 | +0.00 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 456,292 | 598,673 | +142,381 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 176,784 | 591,648 | +414,864 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 649,300 | 589,561 | -59,739 | 0.01 | 0.01 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 504,000 | 577,700 | +73,700 | 0.01 | 0.01 | +0.00 | buy |
| Ikarian Capital, LLC | 593,374 | 575,712 | -17,662 | 0.69 | 0.45 | -0.24 | sell |
| Nuveen, LLC | 205,480 | 565,544 | +360,064 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 557,018 | 545,557 | -11,461 | 0.00 | 0.00 | +0.00 | sell |
| BAKER BROS. ADVISORS LP | 542,539 | 542,539 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Ensign Peak Advisors, Inc | 554,981 | 531,431 | -23,550 | 0.01 | 0.01 | +0.00 | sell |
| Alta Partners Management Company, L.P. | 509,917 | 509,917 | 0 | 4.85 | 2.97 | -1.88 | hold |
| CITADEL ADVISORS LLC | 799,034 | 489,226 | -309,808 | 0.00 | 0.00 | -0.00 | sell |
| Sio Capital Management, LLC | 478,343 | 478,343 | 0 | 0.69 | 0.48 | -0.21 | hold |
| PRINCIPAL FINANCIAL GROUP INC | 455,700 | 450,595 | -5,105 | 0.00 | 0.00 | +0.00 | sell |
| JPMORGAN CHASE & CO | 449,518 | 418,603 | -30,915 | 0.00 | 0.00 | +0.00 | sell |
| UBS Group AG | 214,762 | 417,965 | +203,203 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 417,956 | 405,698 | -12,258 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 277,703 | 390,058 | +112,355 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 360,417 | 371,291 | +10,874 | 0.01 | 0.01 | -0.00 | buy |
| BARCLAYS PLC | 410,406 | 365,826 | -44,580 | 0.00 | 0.00 | +0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 516,628 | 327,393 | -189,235 | 0.01 | 0.01 | -0.00 | sell |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 367,264 | 326,172 | -41,092 | 0.01 | 0.01 | -0.00 | sell |
| CITIGROUP INC | 323,525 | 311,287 | -12,238 | 0.00 | 0.00 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 296,017 | 295,391 | -626 | 0.00 | 0.00 | +0.00 | sell |
| PRUDENTIAL FINANCIAL INC | 252,334 | 281,542 | +29,208 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 19,146 | 279,676 | +260,530 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 72,240 | 264,006 | +191,766 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 259,696 | 260,702 | +1,006 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 138,830 | 256,125 | +117,295 | 0.01 | 0.01 | +0.00 | buy |
| Legal & General Group Plc | 244,971 | 240,643 | -4,328 | 0.00 | 0.00 | +0.00 | sell |
| Eagle Health Investments LP | 240,500 | 240,500 | 0 | 0.36 | 0.32 | -0.04 | hold |
| Tejara Capital Ltd | 256,939 | 231,246 | -25,693 | 0.80 | 0.58 | -0.22 | sell |
| RHUMBLINE ADVISERS | 226,799 | 208,359 | -18,440 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 203,104 | 206,222 | +3,118 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 284,227 | 205,125 | -79,102 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 0 | 195,718 | +195,718 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 57,751 | 189,306 | +131,555 | 0.01 | 0.04 | +0.03 | buy |
| AQR CAPITAL MANAGEMENT LLC | 152,138 | 186,324 | +34,186 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 170,200 | 178,000 | +7,800 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 159,867 | 177,103 | +17,236 | 0.01 | 0.01 | -0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 158,123 | 135,701 | -22,422 | 0.02 | 0.02 | -0.00 | sell |
| Rafferty Asset Management, LLC | 114,785 | 133,766 | +18,981 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 82,758 | 126,058 | +43,300 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 143,938 | 121,080 | -22,858 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 109,620 | 109,620 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 105,965 | 106,977 | +1,012 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 75,445 | 105,412 | +29,967 | 0.00 | 0.00 | +0.00 | buy |
| DIADEMA PARTNERS LP | 0 | 100,000 | +100,000 | 0.00 | 0.36 | +0.36 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 94,801 | 97,891 | +3,090 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 108,315 | 87,773 | -20,542 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 272,170 | 83,059 | -189,111 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 47,136 | 81,611 | +34,475 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 52,676 | 79,696 | +27,020 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 18,376 | 72,991 | +54,615 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 68,574 | +68,574 | 0.00 | 0.00 | +0.00 | buy |
| LMR Partners LLP | 167,800 | 67,800 | -100,000 | 0.01 | 0.00 | -0.01 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 65,741 | 65,741 | 0 | 0.00 | 0.00 | +0.00 | hold |
| THRIVENT FINANCIAL FOR LUTHERANS | 68,149 | 65,006 | -3,143 | 0.00 | 0.00 | -0.00 | sell |
| Persistent Asset Partners Ltd | 0 | 63,550 | +63,550 | 0.00 | 0.18 | +0.18 | buy |
| XTX Topco Ltd | 139,896 | 60,078 | -79,818 | 0.04 | 0.01 | -0.03 | sell |
| Campbell & CO Investment Adviser LLC | 0 | 59,784 | +59,784 | 0.00 | 0.02 | +0.02 | buy |
| SG Americas Securities, LLC | 69,028 | 59,396 | -9,632 | 0.00 | 0.00 | -0.00 | sell |
| PROFUND ADVISORS LLC | 27,660 | 56,693 | +29,033 | 0.01 | 0.01 | +0.01 | buy |
| Quinn Opportunity Partners LLC | 50,976 | 50,976 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Quadrature Capital Ltd | 0 | 49,800 | +49,800 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 33,524 | 49,792 | +16,268 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 49,623 | +49,623 | 0.00 | 0.01 | +0.01 | buy |
| Susquehanna Portfolio Strategies, LLC | 47,432 | 47,432 | 0 | 0.00 | 0.00 | +0.00 | hold |
| State of Alaska, Department of Revenue | 47,531 | 47,323 | -208 | 0.00 | 0.00 | +0.00 | sell |
| MARTINGALE ASSET MANAGEMENT L P | 47,014 | 44,802 | -2,212 | 0.01 | 0.01 | +0.00 | sell |
| Mitsubishi UFJ Asset Management Co., Ltd. | 50,009 | 43,745 | -6,264 | 0.00 | 0.00 | -0.00 | sell |
| Louisiana State Employees Retirement System | 43,400 | 43,300 | -100 | 0.00 | 0.00 | +0.00 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 40,530 | 40,124 | -406 | 0.00 | 0.00 | -0.00 | sell |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 55,968 | 40,118 | -15,850 | 0.00 | 0.00 | -0.00 | sell |
| Virtus Investment Advisers, LLC | 21,798 | 39,764 | +17,966 | 0.04 | 0.07 | +0.03 | buy |
| Quantinno Capital Management LP | 22,881 | 39,272 | +16,391 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 52,929 | 37,722 | -15,207 | 0.00 | 0.00 | -0.00 | sell |