| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 345,360 | 1,531,711 | +1,186,351 | 0.00 | 0.00 | +0.00 | buy |
| Divisadero Street Capital Management, LP | 0 | 497,716 | +497,716 | 0.00 | 0.47 | +0.47 | buy |
| MORGAN STANLEY | 147,332 | 509,568 | +362,236 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 298,248 | 592,865 | +294,617 | 0.00 | 0.00 | +0.00 | buy |
| Soleus Capital Management, L.P. | 0 | 285,000 | +285,000 | 0.00 | 0.28 | +0.28 | buy |
| VANGUARD GROUP INC | 1,100,963 | 1,312,173 | +211,210 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 114,236 | 323,194 | +208,958 | 0.00 | 0.00 | +0.00 | buy |
| THOMPSON SIEGEL & WALMSLEY LLC | 189,863 | 381,265 | +191,402 | 0.04 | 0.09 | +0.05 | buy |
| NORTHERN TRUST CORP | 84,450 | 262,211 | +177,761 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 82,355 | 214,552 | +132,197 | 0.00 | 0.01 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 274,000 | 405,900 | +131,900 | 0.01 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 113,113 | 242,580 | +129,467 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 95,748 | 212,484 | +116,736 | 0.00 | 0.00 | +0.00 | buy |
| APIS CAPITAL ADVISORS, LLC | 0 | 106,000 | +106,000 | 0.00 | 0.54 | +0.54 | buy |
| EcoR1 Capital, LLC | 1,939,288 | 2,030,544 | +91,256 | 1.49 | 1.71 | +0.22 | buy |
| Diametric Capital, LP | 19,597 | 84,858 | +65,261 | 0.30 | 0.65 | +0.34 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 13,247 | 77,848 | +64,601 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 0 | 58,917 | +58,917 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 74,246 | 127,344 | +53,098 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 39,317 | 87,696 | +48,379 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 53,100 | 100,900 | +47,800 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 36,921 | +36,921 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 0 | 36,594 | +36,594 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 0 | 35,850 | +35,850 | 0.00 | 0.01 | +0.01 | buy |
| Squarepoint Ops LLC | 64,795 | 93,796 | +29,001 | 0.00 | 0.00 | +0.00 | buy |
| ANCHOR CAPITAL ADVISORS LLC | 60,179 | 87,661 | +27,482 | 0.02 | 0.04 | +0.01 | buy |
| Russell Investments Group, Ltd. | 0 | 18,112 | +18,112 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 7,794 | 25,233 | +17,439 | 0.00 | 0.01 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 0 | 17,399 | +17,399 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 15,537 | +15,537 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0 | 14,038 | +14,038 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 13,889 | +13,889 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 13,750 | +13,750 | 0.00 | 0.00 | +0.00 | buy |
| Magnetar Financial LLC | 0 | 13,731 | +13,731 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 0 | 13,478 | +13,478 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 12,840 | +12,840 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 78,213 | 90,415 | +12,202 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 12,068 | +12,068 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 1 | 9,103 | +9,102 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 8,100 | +8,100 | 0.00 | 0.00 | +0.00 | buy |
| Opaleye Management Inc. | 2,852,070 | 2,860,000 | +7,930 | 8.24 | 8.25 | +0.01 | buy |
| Steward Partners Investment Advisory, LLC | 7,499 | 14,064 | +6,565 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 0 | 6,137 | +6,137 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 17,316 | 23,050 | +5,734 | 0.00 | 0.00 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 25,283 | 29,213 | +3,930 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 0 | 2,852 | +2,852 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 2,617 | +2,617 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 4,118 | 5,948 | +1,830 | 0.01 | 0.01 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 1,600 | +1,600 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 22,404 | 23,754 | +1,350 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 44,661 | 45,790 | +1,129 | 0.00 | 0.00 | -0.00 | buy |
| AMALGAMATED BANK | 0 | 876 | +876 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 0 | 455 | +455 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 77 | 433 | +356 | 0.00 | 0.00 | +0.00 | buy |
| Vermillion & White Wealth Management Group, LLC | 0 | 150 | +150 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 0 | 62 | +62 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 100 | 102 | +2 | 0.00 | 0.00 | -0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 135,270 | 135,270 | 0 | 0.04 | 0.05 | +0.00 | hold |
| Nantahala Capital Management, LLC | 1,175,951 | 1,175,951 | 0 | 1.26 | 1.19 | -0.08 | hold |
| CHICAGO TRUST Co NA | 16,700 | 16,700 | 0 | 0.04 | 0.03 | -0.00 | hold |
| Truvestments Capital LLC | 1,183 | 1,183 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Quantum Private Wealth, LLC | 11,500 | 11,500 | 0 | 0.06 | 0.05 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 54,275 | 54,275 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Hillsdale Investment Management Inc. | 18,983 | 18,903 | -80 | 0.01 | 0.01 | -0.00 | sell |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 20,419 | 20,182 | -237 | 0.06 | 0.05 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 2,971 | 2,558 | -413 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 634 | 0 | -634 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 686 | 0 | -686 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 1,500 | 0 | -1,500 | 0.00 | 0.00 | -0.00 | sell |
| Point72 (DIFC) Ltd | 1,800 | 0 | -1,800 | 0.00 | 0.00 | -0.00 | sell |
| State of Tennessee, Department of Treasury | 13,950 | 12,000 | -1,950 | 0.00 | 0.00 | -0.00 | sell |
| Y-Intercept (Hong Kong) Ltd | 13,400 | 10,991 | -2,409 | 0.01 | 0.00 | -0.01 | sell |
| BLAIR WILLIAM & CO/IL | 34,900 | 32,400 | -2,500 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 4,472 | 0 | -4,472 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 402,428 | 392,715 | -9,713 | 0.01 | 0.01 | -0.00 | sell |
| Jefferies Financial Group Inc. | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 10,189 | 0 | -10,189 | 0.00 | 0.00 | -0.00 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 232,532 | 222,083 | -10,449 | 0.01 | 0.01 | -0.00 | sell |
| Brevan Howard Capital Management LP | 10,693 | 0 | -10,693 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 10,795 | 0 | -10,795 | 0.04 | 0.00 | -0.04 | sell |
| PDT Partners, LLC | 25,755 | 14,891 | -10,864 | 0.02 | 0.01 | -0.01 | sell |
| Cannon Global Investment Management, LLC | 11,400 | 0 | -11,400 | 0.41 | 0.00 | -0.41 | sell |
| XTX Topco Ltd | 11,797 | 0 | -11,797 | 0.01 | 0.00 | -0.01 | sell |
| LMR Partners LLP | 13,574 | 0 | -13,574 | 0.00 | 0.00 | -0.00 | sell |
| State of Wyoming | 26,443 | 11,503 | -14,940 | 0.05 | 0.02 | -0.03 | sell |
| Jump Financial, LLC | 16,303 | 0 | -16,303 | 0.00 | 0.00 | -0.00 | sell |
| Quantessence Capital LLC | 16,590 | 0 | -16,590 | 0.05 | 0.00 | -0.05 | sell |
| ExodusPoint Capital Management, LP | 17,102 | 0 | -17,102 | 0.00 | 0.00 | -0.00 | sell |
| Westside Investment Management, Inc. | 493,650 | 472,790 | -20,860 | 1.36 | 1.25 | -0.12 | sell |
| Jain Global LLC | 22,401 | 0 | -22,401 | 0.01 | 0.00 | -0.01 | sell |
| Schonfeld Strategic Advisors LLC | 24,213 | 0 | -24,213 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 24,492 | 0 | -24,492 | 0.00 | 0.00 | -0.00 | sell |
| OMERS ADMINISTRATION Corp | 35,300 | 0 | -35,300 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 50,205 | 0 | -50,205 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 86,848 | 34,557 | -52,291 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 57,235 | 0 | -57,235 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 175,220 | 109,379 | -65,841 | 0.00 | 0.00 | -0.00 | sell |
| Aristides Capital LLC | 241,587 | 167,587 | -74,000 | 1.16 | 0.76 | -0.40 | sell |