| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Acuitas Investments, LLC | 219,000 | 492,054 | +273,054 | 0.54 | 1.13 | +0.59 | buy |
| Opaleye Management Inc. | 2,430,270 | 2,529,887 | +99,617 | 3.30 | 2.95 | -0.35 | buy |
| VANGUARD GROUP INC | 976,436 | 1,027,688 | +51,252 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 4,757 | 50,443 | +45,686 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 97,264 | 137,488 | +40,224 | 0.00 | 0.00 | +0.00 | buy |
| Westside Investment Management, Inc. | 528,310 | 563,110 | +34,800 | 0.63 | 0.63 | -0.00 | buy |
| Parkman Healthcare Partners LLC | 165,000 | 199,168 | +34,168 | 0.13 | 0.12 | -0.00 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 29,900 | +29,900 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 0 | 27,979 | +27,979 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 37,507 | 64,590 | +27,083 | 0.00 | 0.00 | +0.00 | buy |
| BAILARD, INC. | 0 | 22,639 | +22,639 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 44,642 | 63,424 | +18,782 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 43,600 | 58,310 | +14,710 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 12,958 | +12,958 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 11,914 | 22,858 | +10,944 | 0.01 | 0.02 | +0.01 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 10,900 | +10,900 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 10,688 | +10,688 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 0 | 10,564 | +10,564 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 217,629 | 227,256 | +9,627 | 0.00 | 0.00 | -0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 38,305 | 43,078 | +4,773 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,172 | 4,062 | +2,890 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 2,230 | +2,230 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 1,092 | +1,092 | 0.00 | 0.00 | +0.00 | buy |
| Heron Bay Capital Management | 11,030 | 11,515 | +485 | 0.01 | 0.01 | -0.00 | buy |
| NewEdge Advisors, LLC | 175 | 252 | +77 | 0.00 | 0.00 | +0.00 | buy |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 300,000 | 300,000 | 0 | 0.07 | 0.07 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 350 | 350 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bank of New York Mellon Corp | 79,402 | 79,402 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Plante Moran Financial Advisors, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NewSquare Capital LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHICAGO TRUST Co NA | 16,700 | 16,700 | 0 | 0.02 | 0.02 | -0.00 | hold |
| Stratos Wealth Partners, LTD. | 26,878 | 26,878 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Financial Advisors Network, Inc. | 10,633 | 10,633 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Truvestments Capital LLC | 1,848 | 1,848 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Quantum Private Wealth, LLC | 11,500 | 11,500 | 0 | 0.02 | 0.02 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 13,239 | 13,239 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BLAIR WILLIAM & CO/IL | 36,979 | 36,979 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 81,403 | 81,403 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 43,200 | 42,700 | -500 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 805 | 0 | -805 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 11,523 | 0 | -11,523 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 14,672 | 0 | -14,672 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 271,462 | 253,362 | -18,100 | 0.03 | 0.02 | -0.00 | sell |
| Jump Financial, LLC | 21,100 | 0 | -21,100 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 186,562 | 161,928 | -24,634 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 25,650 | 0 | -25,650 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 79,552 | 52,500 | -27,052 | 0.00 | 0.00 | -0.00 | sell |
| Hillsdale Investment Management Inc. | 28,800 | 0 | -28,800 | 0.01 | 0.00 | -0.01 | sell |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 110,016 | 78,613 | -31,403 | 0.07 | 0.07 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 80,320 | 20,393 | -59,927 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 65,210 | 0 | -65,210 | 0.00 | 0.00 | -0.00 | sell |
| Informed Momentum Co LLC | 256,623 | 0 | -256,623 | 0.21 | 0.00 | -0.21 | sell |