| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAR1 Capital Management, LLC | 52,116 | 1,871,455 | +1,819,339 | 0.06 | 2.16 | +2.10 | buy |
| Vestal Point Capital, LP | 465,000 | 1,773,326 | +1,308,326 | 0.28 | 0.95 | +0.67 | buy |
| T. Rowe Price Investment Management, Inc. | 7,254,132 | 8,519,192 | +1,265,060 | 0.08 | 0.11 | +0.04 | buy |
| Pictet Asset Management Holding SA | 1,329,108 | 2,558,865 | +1,229,757 | 0.02 | 0.05 | +0.03 | buy |
| Artisan Partners Limited Partnership | 0 | 1,099,719 | +1,099,719 | 0.00 | 0.03 | +0.03 | buy |
| Alyeska Investment Group, L.P. | 859,108 | 1,941,123 | +1,082,015 | 0.04 | 0.11 | +0.07 | buy |
| MILLENNIUM MANAGEMENT LLC | 369,767 | 1,257,950 | +888,183 | 0.00 | 0.02 | +0.01 | buy |
| Clearstead Advisors, LLC | 0 | 737,990 | +737,990 | 0.00 | 0.13 | +0.13 | buy |
| GOLDMAN SACHS GROUP INC | 3,835,803 | 4,407,255 | +571,452 | 0.01 | 0.01 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 379,051 | 935,692 | +556,641 | 0.00 | 0.01 | +0.01 | buy |
| BlackRock, Inc. | 12,715,201 | 13,034,434 | +319,233 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 2,374,303 | 2,692,175 | +317,872 | 0.01 | 0.01 | +0.00 | buy |
| BRAIDWELL LP | 0 | 296,324 | +296,324 | 0.00 | 0.19 | +0.19 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,458,131 | 3,727,114 | +268,983 | 0.00 | 0.00 | +0.00 | buy |
| Privium Fund Management B.V. | 0 | 254,857 | +254,857 | 0.00 | 1.02 | +1.02 | buy |
| Woodline Partners LP | 114,082 | 364,082 | +250,000 | 0.01 | 0.03 | +0.02 | buy |
| MARSHALL WACE, LLP | 763,892 | 991,268 | +227,376 | 0.01 | 0.02 | +0.01 | buy |
| GREAT LAKES ADVISORS, LLC | 0 | 227,110 | +227,110 | 0.00 | 0.04 | +0.04 | buy |
| Foresite Capital Management VI LLC | 1,000,000 | 1,209,971 | +209,971 | 4.99 | 5.05 | +0.06 | buy |
| BANK OF AMERICA CORP /DE/ | 932,144 | 1,134,183 | +202,039 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 195,108 | +195,108 | 0.00 | 0.01 | +0.01 | buy |
| UBS Group AG | 2,404,704 | 2,571,344 | +166,640 | 0.01 | 0.01 | +0.00 | buy |
| SECTOR GAMMA AS | 0 | 162,710 | +162,710 | 0.00 | 0.74 | +0.74 | buy |
| JPMORGAN CHASE & CO | 171,948 | 323,989 | +152,041 | 0.00 | 0.00 | +0.00 | buy |
| Lynx1 Capital Management LP | 1,738,750 | 1,880,303 | +141,553 | 5.81 | 5.71 | -0.11 | buy |
| NORTHERN TRUST CORP | 1,199,744 | 1,310,656 | +110,912 | 0.00 | 0.00 | +0.00 | buy |
| Rhenman & Partners Asset Management AB | 100,000 | 199,000 | +99,000 | 0.15 | 0.47 | +0.32 | buy |
| Lumbard & Kellner, LLC | 0 | 94,782 | +94,782 | 0.00 | 0.63 | +0.63 | buy |
| Man Group plc | 48,994 | 139,045 | +90,051 | 0.00 | 0.01 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 38,478 | 128,119 | +89,641 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 78,567 | +78,567 | 0.00 | 0.03 | +0.03 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 47,459 | 111,694 | +64,235 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 38,438 | 102,579 | +64,141 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 12,700 | 71,179 | +58,479 | 0.01 | 0.05 | +0.04 | buy |
| GROUPAMA ASSET MANAGMENT | 151,591 | 207,130 | +55,539 | 0.04 | 0.06 | +0.02 | buy |
| SEI INVESTMENTS CO | 0 | 52,235 | +52,235 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 43,362 | +43,362 | 0.00 | 0.03 | +0.03 | buy |
| Holocene Advisors, LP | 3,152,734 | 3,195,429 | +42,695 | 0.11 | 0.15 | +0.04 | buy |
| POLEN CAPITAL MANAGEMENT LLC | 26,900 | 65,301 | +38,401 | 0.00 | 0.01 | +0.01 | buy |
| NOMURA ASSET MANAGEMENT CO LTD | 0 | 36,732 | +36,732 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 0 | 34,425 | +34,425 | 0.00 | 0.01 | +0.01 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 129,409 | 162,576 | +33,167 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 30,570 | +30,570 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 70,830 | 99,503 | +28,673 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 1,265 | 25,935 | +24,670 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 15,497 | 39,893 | +24,396 | 0.00 | 0.00 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 23,000 | +23,000 | 0.00 | 0.05 | +0.05 | buy |
| Nuveen, LLC | 275,508 | 295,586 | +20,078 | 0.00 | 0.00 | +0.00 | buy |
| Amundi | 0 | 18,604 | +18,604 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 291,936 | 310,196 | +18,260 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 18,131 | +18,131 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 23,898 | 40,643 | +16,745 | 0.03 | 0.06 | +0.03 | buy |
| OSAIC HOLDINGS, INC. | 0 | 16,413 | +16,413 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 16,110 | +16,110 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 15,861 | +15,861 | 0.00 | 0.06 | +0.06 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 34,768 | 50,475 | +15,707 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 105,086 | 120,368 | +15,282 | 0.00 | 0.00 | +0.00 | buy |
| CONTRAVISORY INVESTMENT MANAGEMENT, INC. | 0 | 14,451 | +14,451 | 0.00 | 0.06 | +0.06 | buy |
| Creative Planning | 60,766 | 74,069 | +13,303 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 12,658 | +12,658 | 0.00 | 0.00 | +0.00 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 153,781 | 166,181 | +12,400 | 0.02 | 0.02 | +0.01 | buy |
| SIMPLEX TRADING, LLC | 0 | 12,315 | +12,315 | 0.00 | 0.01 | +0.01 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 38,669 | 50,900 | +12,231 | 0.00 | 0.00 | +0.00 | buy |
| B. Riley Wealth Advisors, Inc. | 0 | 12,213 | +12,213 | 0.00 | 0.01 | +0.01 | buy |
| Atria Investments, Inc | 0 | 12,112 | +12,112 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 0 | 11,059 | +11,059 | 0.00 | 0.00 | +0.00 | buy |
| DnB Asset Management AS | 0 | 10,959 | +10,959 | 0.00 | 0.00 | +0.00 | buy |
| Gilbert & Cook, Inc. | 0 | 10,871 | +10,871 | 0.00 | 0.03 | +0.03 | buy |
| Bellevue Group AG | 7,138 | 17,766 | +10,628 | 0.00 | 0.01 | +0.01 | buy |
| RAYMOND JAMES FINANCIAL INC | 25,592 | 34,383 | +8,791 | 0.00 | 0.00 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 73,581 | 82,357 | +8,776 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 6,263,371 | 6,272,001 | +8,630 | 0.00 | 0.00 | +0.00 | buy |
| Pinnacle Wealth Planning Services, Inc. | 2,957 | 11,406 | +8,449 | 0.01 | 0.02 | +0.02 | buy |
| ALPS ADVISORS INC | 120,718 | 129,105 | +8,387 | 0.01 | 0.01 | +0.00 | buy |
| CITIGROUP INC | 30,945 | 39,278 | +8,333 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 12,941 | 20,978 | +8,037 | 0.01 | 0.01 | +0.01 | buy |
| STEMPOINT CAPITAL LP | 419,058 | 426,561 | +7,503 | 1.19 | 1.57 | +0.39 | buy |
| Knights of Columbus Asset Advisors LLC | 49,007 | 56,329 | +7,322 | 0.05 | 0.06 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,200,475 | 1,207,399 | +6,924 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 762,087 | 768,039 | +5,952 | 0.00 | 0.00 | +0.00 | buy |
| E Fund Management Co., Ltd. | 13,612 | 18,942 | +5,330 | 0.01 | 0.01 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 94,582 | 99,554 | +4,972 | 0.02 | 0.02 | -0.00 | buy |
| Pathstone Holdings, LLC | 51,424 | 56,325 | +4,901 | 0.00 | 0.00 | +0.00 | buy |
| Empowered Funds, LLC | 11,325 | 15,787 | +4,462 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 26,313 | 30,170 | +3,857 | 0.00 | 0.00 | +0.00 | buy |
| D.A. DAVIDSON & CO. | 106,933 | 110,235 | +3,302 | 0.01 | 0.01 | +0.00 | buy |
| INTRUST BANK NA | 11,164 | 14,339 | +3,175 | 0.02 | 0.02 | +0.01 | buy |
| FIFTH THIRD BANCORP | 0 | 2,847 | +2,847 | 0.00 | 0.00 | +0.00 | buy |
| XPONANCE, INC. | 10,497 | 13,240 | +2,743 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 75,164 | 77,558 | +2,394 | 0.01 | 0.01 | +0.00 | buy |
| CWM, LLC | 2,606 | 4,651 | +2,045 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 36,607 | 38,545 | +1,938 | 0.01 | 0.01 | +0.00 | buy |
| GUGGENHEIM CAPITAL LLC | 12,468 | 13,825 | +1,357 | 0.00 | 0.00 | +0.00 | buy |
| Dana Investment Advisors, Inc. | 50,582 | 51,922 | +1,340 | 0.02 | 0.03 | +0.01 | buy |
| RHUMBLINE ADVISERS | 183,000 | 184,248 | +1,248 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 7,127 | 8,272 | +1,145 | 0.00 | 0.00 | +0.00 | buy |
| Kemnay Advisory Services Inc. | 0 | 1,134 | +1,134 | 0.00 | 0.00 | +0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 15,064 | 16,194 | +1,130 | 0.00 | 0.00 | +0.00 | buy |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 50,933 | 52,062 | +1,129 | 0.35 | 0.42 | +0.06 | buy |
| NBC SECURITIES, INC. | 6,536 | 7,617 | +1,081 | 0.01 | 0.01 | +0.00 | buy |