| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 13,834,956 | 12,053,345 | -1,781,611 | 0.00 | 0.00 | -0.00 | sell |
| BAILLIE GIFFORD & CO | 12,090,040 | 11,955,323 | -134,717 | 0.14 | 0.12 | -0.02 | sell |
| VANGUARD GROUP INC | 11,799,757 | 11,810,735 | +10,978 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 7,413,354 | 7,538,468 | +125,114 | 0.01 | 0.01 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 4,367,234 | 6,582,295 | +2,215,061 | 0.01 | 0.01 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 6,766,916 | 6,262,277 | -504,639 | 0.02 | 0.02 | -0.01 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 11,409,598 | 5,664,733 | -5,744,865 | 0.03 | 0.01 | -0.02 | sell |
| Temasek Holdings (Private) Ltd | 5,355,832 | 5,355,832 | 0 | 0.29 | 0.29 | -0.00 | hold |
| Capital Research Global Investors | 4,765,137 | 4,750,579 | -14,558 | 0.01 | 0.01 | -0.00 | sell |
| STATE STREET CORP | 4,460,757 | 4,517,994 | +57,237 | 0.00 | 0.00 | -0.00 | buy |
| NORGES BANK | 3,047,606 | 3,947,387 | +899,781 | 0.01 | 0.01 | +0.00 | buy |
| Crestline Management, LP | 4,160,732 | 3,860,732 | -300,000 | 89.45 | 86.33 | -3.12 | sell |
| BAKER BROS. ADVISORS LP | 3,731,695 | 3,731,695 | 0 | 0.56 | 0.51 | -0.05 | hold |
| T. Rowe Price Investment Management, Inc. | 0 | 3,246,934 | +3,246,934 | 0.00 | 0.03 | +0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,037,176 | 3,172,305 | +135,129 | 0.00 | 0.00 | -0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 3,154,387 | 3,137,140 | -17,247 | 0.02 | 0.01 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 2,100,856 | 2,412,928 | +312,072 | 0.01 | 0.01 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 2,213,947 | +2,213,947 | 0.00 | 0.07 | +0.07 | buy |
| GOLDMAN SACHS GROUP INC | 1,672,078 | 1,865,324 | +193,246 | 0.00 | 0.00 | -0.00 | buy |
| Fisher Asset Management, LLC | 1,364,959 | 1,515,991 | +151,032 | 0.01 | 0.01 | +0.00 | buy |
| MARSHALL WACE, LLP | 2,188,422 | 1,405,250 | -783,172 | 0.04 | 0.02 | -0.02 | sell |
| MORGAN STANLEY | 1,253,603 | 1,312,016 | +58,413 | 0.00 | 0.00 | -0.00 | buy |
| CITADEL ADVISORS LLC | 1,169,683 | 1,248,953 | +79,270 | 0.02 | 0.02 | -0.00 | buy |
| NORTHERN TRUST CORP | 1,132,173 | 1,201,709 | +69,536 | 0.00 | 0.00 | +0.00 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 1,081,578 | 1,072,983 | -8,595 | 0.01 | 0.01 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,009,896 | 1,056,019 | +46,123 | 0.00 | 0.00 | -0.00 | buy |
| UBS Group AG | 788,429 | 950,764 | +162,335 | 0.00 | 0.00 | +0.00 | buy |
| Aberdeen Group plc | 759,815 | 902,751 | +142,936 | 0.02 | 0.02 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,493,068 | 900,501 | -592,567 | 0.02 | 0.01 | -0.01 | sell |
| Casdin Capital, LLC | 990,000 | 890,000 | -100,000 | 1.10 | 1.13 | +0.03 | sell |
| Candriam S.C.A. | 858,162 | 844,249 | -13,913 | 0.07 | 0.07 | -0.00 | sell |
| Siren, L.L.C. | 821,513 | 821,513 | 0 | 0.63 | 0.59 | -0.04 | hold |
| Bank of New York Mellon Corp | 1,103,892 | 790,756 | -313,136 | 0.00 | 0.00 | -0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 301,973 | 770,527 | +468,554 | 0.02 | 0.04 | +0.02 | buy |
| STEMPOINT CAPITAL LP | 667,078 | 707,915 | +40,837 | 2.90 | 3.19 | +0.29 | buy |
| BANK OF AMERICA CORP /DE/ | 447,757 | 650,222 | +202,465 | 0.00 | 0.00 | +0.00 | buy |
| Cercano Management LLC | 625,000 | 625,000 | 0 | 0.25 | 0.25 | -0.00 | hold |
| MASTERS CAPITAL MANAGEMENT LLC | 0 | 600,000 | +600,000 | 0.00 | 1.62 | +1.62 | buy |
| Nuveen, LLC | 322,945 | 595,217 | +272,272 | 0.00 | 0.00 | +0.00 | buy |
| SEGALL BRYANT & HAMILL, LLC | 281,139 | 500,559 | +219,420 | 0.06 | 0.10 | +0.04 | buy |
| TD ASSET MANAGEMENT INC | 308,580 | 496,290 | +187,710 | 0.00 | 0.01 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 587,785 | 473,695 | -114,090 | 0.02 | 0.01 | -0.00 | sell |
| Yiheng Capital Management, L.P. | 469,981 | 469,981 | 0 | 2.25 | 2.38 | +0.14 | hold |
| BARCLAYS PLC | 240,648 | 425,981 | +185,333 | 0.00 | 0.00 | +0.00 | buy |
| Pictet Asset Management Holding SA | 343,959 | 415,112 | +71,153 | 0.01 | 0.01 | +0.00 | buy |
| Holocene Advisors, LP | 0 | 403,172 | +403,172 | 0.00 | 0.01 | +0.01 | buy |
| Camber Capital Management LP | 1,250,000 | 400,000 | -850,000 | 1.06 | 0.78 | -0.28 | sell |
| Cubist Systematic Strategies, LLC | 0 | 396,586 | +396,586 | 0.00 | 0.06 | +0.06 | buy |
| ROYAL BANK OF CANADA | 14,436 | 390,155 | +375,719 | 0.00 | 0.00 | +0.00 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 291,795 | 386,539 | +94,744 | 0.00 | 0.00 | +0.00 | buy |
| Clarius Group, LLC | 368,995 | 368,995 | 0 | 0.32 | 0.30 | -0.01 | hold |
| Edgestream Partners, L.P. | 0 | 342,923 | +342,923 | 0.00 | 0.13 | +0.13 | buy |
| AMERICAN CENTURY COMPANIES INC | 349,420 | 318,193 | -31,227 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 258,132 | 315,102 | +56,970 | 0.00 | 0.00 | +0.00 | buy |
| Pier Capital, LLC | 335,504 | 314,796 | -20,708 | 0.76 | 0.67 | -0.09 | sell |
| AXA S.A. | 293,381 | 293,853 | +472 | 0.01 | 0.01 | -0.00 | buy |
| Hudson Bay Capital Management LP | 250,000 | 290,000 | +40,000 | 0.02 | 0.03 | +0.01 | buy |
| Marex Group plc | 0 | 262,000 | +262,000 | 0.00 | 0.07 | +0.07 | buy |
| Swiss National Bank | 250,900 | 250,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Palo Alto Investors LP | 0 | 239,809 | +239,809 | 0.00 | 0.71 | +0.71 | buy |
| Invesco Ltd. | 189,427 | 219,795 | +30,368 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 190,256 | 212,503 | +22,247 | 0.00 | 0.00 | +0.00 | buy |
| TWINBEECH CAPITAL LP | 72,022 | 210,370 | +138,348 | 0.02 | 0.07 | +0.05 | buy |
| EDMOND DE ROTHSCHILD HOLDING S.A. | 205,680 | 205,680 | 0 | 0.05 | 0.05 | -0.00 | hold |
| SCS Capital Management LLC | 197,998 | 197,998 | 0 | 0.03 | 0.03 | -0.00 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 173,100 | 195,700 | +22,600 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 188,403 | 191,613 | +3,210 | 0.00 | 0.00 | -0.00 | buy |
| Soleus Capital Management, L.P. | 135,000 | 182,110 | +47,110 | 0.14 | 0.18 | +0.03 | buy |
| GROUPAMA ASSET MANAGMENT | 144,488 | 175,531 | +31,043 | 0.04 | 0.04 | -0.00 | buy |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 183,392 | 171,553 | -11,839 | 0.02 | 0.02 | -0.00 | sell |
| DAFNA Capital Management LLC | 127,900 | 168,500 | +40,600 | 0.49 | 0.65 | +0.16 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 167,197 | 161,136 | -6,061 | 0.00 | 0.00 | -0.00 | sell |
| Campbell & CO Investment Adviser LLC | 68,185 | 142,708 | +74,523 | 0.07 | 0.13 | +0.05 | buy |
| State of New Jersey Common Pension Fund D | 93,590 | 137,880 | +44,290 | 0.01 | 0.01 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 156,252 | 135,969 | -20,283 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 88,507 | 134,703 | +46,196 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 151,962 | 131,755 | -20,207 | 0.00 | 0.00 | -0.00 | sell |
| Rafferty Asset Management, LLC | 129,135 | 122,262 | -6,873 | 0.01 | 0.01 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 117,535 | 119,327 | +1,792 | 0.00 | 0.00 | -0.00 | buy |
| Engineers Gate Manager LP | 17,198 | 116,101 | +98,903 | 0.00 | 0.02 | +0.02 | buy |
| Woodline Partners LP | 113,517 | 113,517 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Trexquant Investment LP | 113,224 | 109,242 | -3,982 | 0.02 | 0.02 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 0 | 102,033 | +102,033 | 0.00 | 0.00 | +0.00 | buy |
| Rhenman & Partners Asset Management AB | 100,000 | 100,000 | 0 | 0.16 | 0.18 | +0.02 | hold |
| Savvy Advisors, Inc. | 0 | 97,793 | +97,793 | 0.00 | 0.09 | +0.09 | buy |
| Integrated Wealth Concepts LLC | 0 | 96,046 | +96,046 | 0.00 | 0.01 | +0.01 | buy |
| Polar Asset Management Partners Inc. | 20,952 | 91,600 | +70,648 | 0.01 | 0.03 | +0.02 | buy |
| WELLS FARGO & COMPANY/MN | 77,282 | 89,639 | +12,357 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 0 | 85,840 | +85,840 | 0.00 | 0.03 | +0.03 | buy |
| JANE STREET GROUP, LLC | 213,673 | 85,332 | -128,341 | 0.01 | 0.00 | -0.00 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 79,891 | 79,627 | -264 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 74,765 | 79,075 | +4,310 | 0.01 | 0.01 | +0.00 | buy |
| ALPS ADVISORS INC | 111,375 | 78,356 | -33,019 | 0.01 | 0.01 | -0.00 | sell |
| CITIGROUP INC | 194,004 | 76,315 | -117,689 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 77,590 | 71,866 | -5,724 | 0.01 | 0.01 | -0.00 | sell |
| Man Group plc | 169,385 | 70,028 | -99,357 | 0.01 | 0.00 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 67,917 | 67,917 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TT International Asset Management LTD | 0 | 65,000 | +65,000 | 0.00 | 0.17 | +0.17 | buy |
| Graham Capital Management, L.P. | 43,005 | 64,799 | +21,794 | 0.02 | 0.03 | +0.01 | buy |
| FRANKLIN RESOURCES INC | 83,248 | 64,525 | -18,723 | 0.00 | 0.00 | -0.00 | sell |