| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,650,000 | 9,328,739 | +6,678,739 | 0.01 | 0.06 | +0.05 | buy |
| JANUS HENDERSON GROUP PLC | 0 | 5,120,573 | +5,120,573 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 175,628 | 1,619,627 | +1,443,999 | 0.00 | 0.01 | +0.01 | buy |
| MORGAN STANLEY | 0 | 1,382,689 | +1,382,689 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 991,971 | +991,971 | 0.00 | 0.00 | +0.00 | buy |
| Integral Health Asset Management, LLC | 0 | 950,000 | +950,000 | 0.00 | 0.31 | +0.31 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,410,317 | 2,179,135 | +768,818 | 0.00 | 0.01 | +0.00 | buy |
| Verition Fund Management LLC | 0 | 485,436 | +485,436 | 0.00 | 0.02 | +0.02 | buy |
| Artia Global Partners LP | 0 | 421,359 | +421,359 | 0.00 | 0.34 | +0.34 | buy |
| ACUTA CAPITAL PARTNERS, LLC | 0 | 397,884 | +397,884 | 0.00 | 0.85 | +0.85 | buy |
| NEOS Investment Management LLC | 351,905 | 623,430 | +271,525 | 0.08 | 0.13 | +0.05 | buy |
| GOLDMAN SACHS GROUP INC | 2,023,672 | 2,243,814 | +220,142 | 0.00 | 0.00 | +0.00 | buy |
| Global IMC LLC | 0 | 195,087 | +195,087 | 0.00 | 0.15 | +0.15 | buy |
| Rock Springs Capital Management LP | 7,983,851 | 8,142,109 | +158,258 | 0.46 | 0.68 | +0.23 | buy |
| TD ASSET MANAGEMENT INC | 0 | 148,000 | +148,000 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 126,500 | +126,500 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 118,978 | +118,978 | 0.00 | 0.00 | +0.00 | buy |
| J. Goldman & Co LP | 162,000 | 278,588 | +116,588 | 0.02 | 0.04 | +0.02 | buy |
| Knoll Capital Management, LLC | 160,470 | 260,470 | +100,000 | 0.31 | 0.53 | +0.23 | buy |
| FRED ALGER MANAGEMENT, LLC | 102,531 | 194,879 | +92,348 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 86,873 | +86,873 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 78,718 | +78,718 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 32,160 | 109,327 | +77,167 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 75,787 | +75,787 | 0.00 | 0.02 | +0.02 | buy |
| Squarepoint Ops LLC | 0 | 47,687 | +47,687 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 311,060 | 351,729 | +40,669 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 38,122 | +38,122 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 14,686 | 47,030 | +32,344 | 0.00 | 0.00 | +0.00 | buy |
| Index Fund Advisors, Inc. | 0 | 30,000 | +30,000 | 0.00 | 0.01 | +0.01 | buy |
| Knott David M Jr | 0 | 30,000 | +30,000 | 0.00 | 0.04 | +0.04 | buy |
| SIMPLEX TRADING, LLC | 0 | 29,242 | +29,242 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 26,179 | +26,179 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3 | 17,435 | +17,432 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 16,221 | +16,221 | 0.00 | 0.00 | +0.00 | buy |
| GTS SECURITIES LLC | 0 | 15,664 | +15,664 | 0.00 | 0.00 | +0.00 | buy |
| Total Clarity Wealth Management, Inc. | 0 | 11,860 | +11,860 | 0.00 | 0.01 | +0.01 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 47,169 | 55,903 | +8,734 | 0.00 | 0.00 | +0.00 | buy |
| Advisors Preferred, LLC | 0 | 8,262 | +8,262 | 0.00 | 0.00 | +0.00 | buy |
| Forefront Analytics, LLC | 36,124 | 43,817 | +7,693 | 0.04 | 0.07 | +0.03 | buy |
| Tower Research Capital LLC (TRC) | 0 | 7,145 | +7,145 | 0.00 | 0.00 | +0.00 | buy |
| Newbridge Financial Services Group, Inc. | 9,500 | 11,700 | +2,200 | 0.01 | 0.02 | +0.01 | buy |
| Point72 Asset Management, L.P. | 0 | 1,900 | +1,900 | 0.00 | 0.00 | +0.00 | buy |
| GAMMA Investing LLC | 4,612 | 5,987 | +1,375 | 0.00 | 0.00 | -0.00 | buy |
| PFG Investments, LLC | 30,000 | 31,200 | +1,200 | 0.01 | 0.01 | -0.01 | buy |
| BFSG, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATUREFD, LLC | 0 | 820 | +820 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 0 | 739 | +739 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 13 | 413 | +400 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 3,909 | 4,071 | +162 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 96,630 | 96,630 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ALKEON CAPITAL MANAGEMENT LLC | 4,238,100 | 4,238,100 | 0 | 0.06 | 0.08 | +0.01 | hold |
| Plante Moran Financial Advisors, LLC | 48 | 48 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MANGROVE PARTNERS IM, LLC | 8,752,893 | 8,752,893 | 0 | 1.37 | 2.02 | +0.65 | hold |
| Allworth Financial LP | 1,500 | 1,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Arax Advisory Partners | 4,000 | 4,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Clearline Capital LP | 3,326,718 | 3,326,718 | 0 | 0.86 | 1.08 | +0.23 | hold |
| Rubric Capital Management LP | 13,552,997 | 13,552,997 | 0 | 1.17 | 1.32 | +0.15 | hold |
| Centiva Capital, LP | 25,000 | 25,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| LEVEL FOUR ADVISORY SERVICES, LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| New England Capital Financial Advisors LLC | 300 | 300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BARCLAYS PLC | 38 | 38 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRIMECAP MANAGEMENT CO/CA/ | 54,000 | 54,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIT INVESTMENT ASSOCIATES INC | 970 | 970 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Spire Wealth Management | 250 | 0 | -250 | 0.00 | 0.00 | -0.00 | sell |
| OneDigital Investment Advisors LLC | 18,902 | 18,513 | -389 | 0.00 | 0.00 | +0.00 | sell |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1,800 | 0 | -1,800 | 0.00 | 0.00 | -0.00 | sell |
| Clear Harbor Asset Management, LLC | 59,754 | 46,000 | -13,754 | 0.01 | 0.01 | +0.00 | sell |
| Scientech Research LLC | 13,955 | 0 | -13,955 | 0.03 | 0.00 | -0.03 | sell |
| MARSHALL WACE, LLP | 14,883 | 0 | -14,883 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 20,322 | 0 | -20,322 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 58,217 | 28,577 | -29,640 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 50,100 | 0 | -50,100 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 62,843 | 0 | -62,843 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 1,798,009 | 1,672,309 | -125,700 | 0.01 | 0.01 | +0.00 | sell |
| Monaco Asset Management SAM | 676,494 | 405,000 | -271,494 | 0.60 | 0.59 | -0.01 | sell |
| CITADEL ADVISORS LLC | 324,819 | 43,907 | -280,912 | 0.00 | 0.00 | -0.00 | sell |
| Tidal Investments LLC | 319,390 | 0 | -319,390 | 0.02 | 0.00 | -0.02 | sell |
| 683 Capital Management, LLC | 6,200,000 | 5,750,000 | -450,000 | 1.43 | 1.94 | +0.50 | sell |
| Aberdeen Group plc | 1,551,082 | 817,309 | -733,773 | 0.01 | 0.01 | -0.00 | sell |
| DAFNA Capital Management LLC | 778,813 | 0 | -778,813 | 0.43 | 0.00 | -0.43 | sell |
| Tejara Capital Ltd | 3,713,129 | 2,470,184 | -1,242,945 | 3.59 | 3.02 | -0.57 | sell |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 7,370,838 | 3,653,494 | -3,717,344 | 0.78 | 0.51 | -0.27 | sell |
| Soleus Capital Management, L.P. | 9,777,419 | 2,616,953 | -7,160,466 | 2.51 | 0.76 | -1.75 | sell |