| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MANGROVE PARTNERS IM, LLC | 5,531,547 | 8,752,893 | +3,221,346 | 0.54 | 1.37 | +0.83 | buy |
| Rubric Capital Management LP | 11,616,120 | 13,552,997 | +1,936,877 | 0.63 | 1.17 | +0.54 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 800,000 | 2,650,000 | +1,850,000 | 0.00 | 0.01 | +0.01 | buy |
| Aberdeen Group plc | 0 | 1,551,082 | +1,551,082 | 0.00 | 0.01 | +0.01 | buy |
| ALKEON CAPITAL MANAGEMENT LLC | 3,738,100 | 4,238,100 | +500,000 | 0.03 | 0.06 | +0.03 | buy |
| Tejara Capital Ltd | 3,215,001 | 3,713,129 | +498,128 | 2.36 | 3.59 | +1.23 | buy |
| NEOS Investment Management LLC | 41,328 | 351,905 | +310,577 | 0.01 | 0.08 | +0.07 | buy |
| Rock Springs Capital Management LP | 7,676,481 | 7,983,851 | +307,370 | 0.27 | 0.46 | +0.19 | buy |
| Clearline Capital LP | 3,102,723 | 3,326,718 | +223,995 | 0.40 | 0.86 | +0.46 | buy |
| 683 Capital Management, LLC | 6,000,000 | 6,200,000 | +200,000 | 0.78 | 1.43 | +0.65 | buy |
| TWO SIGMA INVESTMENTS, LP | 142,602 | 311,060 | +168,458 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,243,585 | 1,410,317 | +166,732 | 0.00 | 0.00 | +0.00 | buy |
| Knoll Capital Management, LLC | 0 | 160,470 | +160,470 | 0.00 | 0.31 | +0.31 | buy |
| FRED ALGER MANAGEMENT, LLC | 0 | 102,531 | +102,531 | 0.00 | 0.00 | +0.00 | buy |
| Soleus Capital Management, L.P. | 9,677,419 | 9,777,419 | +100,000 | 1.26 | 2.51 | +1.25 | buy |
| Monaco Asset Management SAM | 595,729 | 676,494 | +80,765 | 0.38 | 0.60 | +0.22 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 103,270 | 175,628 | +72,358 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 1,727,570 | 1,798,009 | +70,439 | 0.00 | 0.01 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 62,843 | +62,843 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 0 | 47,169 | +47,169 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 32,160 | +32,160 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 14,883 | +14,883 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 14,686 | +14,686 | 0.00 | 0.00 | +0.00 | buy |
| Newbridge Financial Services Group, Inc. | 0 | 9,500 | +9,500 | 0.00 | 0.01 | +0.01 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 7,364,438 | 7,370,838 | +6,400 | 0.51 | 0.78 | +0.26 | buy |
| Golden State Equity Partners | 14,400 | 20,300 | +5,900 | 0.01 | 0.01 | +0.01 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 1,800 | +1,800 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 3,598 | 3,909 | +311 | 0.00 | 0.00 | +0.00 | buy |
| Spire Wealth Management | 0 | 250 | +250 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 96,630 | 96,630 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Plante Moran Financial Advisors, LLC | 48 | 48 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Allworth Financial LP | 1,500 | 1,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Arax Advisory Partners | 4,000 | 4,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Centiva Capital, LP | 25,000 | 25,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| LEVEL FOUR ADVISORY SERVICES, LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| New England Capital Financial Advisors LLC | 300 | 300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PFG Investments, LLC | 30,000 | 30,000 | 0 | 0.01 | 0.01 | +0.01 | hold |
| US BANCORP \DE\ | 13 | 13 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIT INVESTMENT ASSOCIATES INC | 970 | 970 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HSBC HOLDINGS PLC | 58,217 | 58,217 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GOLDMAN SACHS GROUP INC | 2,023,672 | 2,023,672 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BARCLAYS PLC | 76 | 38 | -38 | 0.00 | 0.00 | -0.00 | sell |
| Clear Harbor Asset Management, LLC | 63,754 | 59,754 | -4,000 | 0.01 | 0.01 | +0.00 | sell |
| OneDigital Investment Advisors LLC | 26,300 | 18,902 | -7,398 | 0.00 | 0.00 | +0.00 | sell |
| XTX Topco Ltd | 11,313 | 0 | -11,313 | 0.00 | 0.00 | -0.00 | sell |
| Tidal Investments LLC | 331,914 | 319,390 | -12,524 | 0.01 | 0.02 | +0.00 | sell |
| Virtu Financial LLC | 34,093 | 20,322 | -13,771 | 0.00 | 0.00 | -0.00 | sell |
| OPPENHEIMER & CO INC | 14,000 | 0 | -14,000 | 0.00 | 0.00 | -0.00 | sell |
| Arcus Capital Partners, LLC | 15,000 | 0 | -15,000 | 0.01 | 0.00 | -0.01 | sell |
| Creative Planning | 15,820 | 0 | -15,820 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 17,285 | 0 | -17,285 | 0.00 | 0.00 | -0.00 | sell |
| Privium Fund Management (UK) Ltd | 24,726 | 0 | -24,726 | 0.03 | 0.00 | -0.03 | sell |
| PRIMECAP MANAGEMENT CO/CA/ | 79,000 | 54,000 | -25,000 | 0.00 | 0.00 | +0.00 | sell |
| Forefront Analytics, LLC | 65,649 | 36,124 | -29,525 | 0.05 | 0.04 | -0.01 | sell |
| Schonfeld Strategic Advisors LLC | 130,600 | 50,100 | -80,500 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 120,584 | 0 | -120,584 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 132,801 | 0 | -132,801 | 0.00 | 0.00 | -0.00 | sell |
| DAFNA Capital Management LLC | 962,513 | 778,813 | -183,700 | 0.39 | 0.43 | +0.04 | sell |
| J. Goldman & Co LP | 445,485 | 162,000 | -283,485 | 0.03 | 0.02 | -0.01 | sell |
| Formidable Asset Management, LLC | 331,914 | 0 | -331,914 | 0.09 | 0.00 | -0.09 | sell |
| Ikarian Capital, LLC | 591,676 | 0 | -591,676 | 0.07 | 0.00 | -0.07 | sell |
| CITADEL ADVISORS LLC | 2,242,425 | 324,819 | -1,917,606 | 0.00 | 0.00 | -0.00 | sell |