| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Woodline Partners LP | 2,883,657 | 4,245,221 | +1,361,564 | 0.50 | 0.62 | +0.12 | buy |
| VANGUARD GROUP INC | 4,791,244 | 5,257,326 | +466,082 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 250,313 | 636,774 | +386,461 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 1,201,021 | 1,474,438 | +273,417 | 0.01 | 0.01 | -0.00 | buy |
| Trexquant Investment LP | 38,117 | 252,586 | +214,469 | 0.01 | 0.06 | +0.04 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 175,705 | +175,705 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 159,108 | +159,108 | 0.00 | 0.17 | +0.17 | buy |
| Parkman Healthcare Partners LLC | 259,920 | 415,535 | +155,615 | 0.60 | 0.86 | +0.26 | buy |
| Ikarian Capital, LLC | 0 | 145,000 | +145,000 | 0.00 | 0.69 | +0.69 | buy |
| Schonfeld Strategic Advisors LLC | 103,860 | 232,794 | +128,934 | 0.02 | 0.03 | +0.01 | buy |
| SG Americas Securities, LLC | 8,642 | 129,292 | +120,650 | 0.00 | 0.01 | +0.01 | buy |
| SIMPLEX TRADING, LLC | 9,723 | 129,860 | +120,137 | 0.01 | 0.06 | +0.06 | buy |
| CITADEL ADVISORS LLC | 354,921 | 467,163 | +112,242 | 0.01 | 0.01 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,151,128 | 1,260,782 | +109,654 | 0.01 | 0.01 | -0.00 | buy |
| Verition Fund Management LLC | 0 | 89,611 | +89,611 | 0.00 | 0.01 | +0.01 | buy |
| Cubist Systematic Strategies, LLC | 0 | 84,463 | +84,463 | 0.00 | 0.02 | +0.02 | buy |
| Granahan Investment Management, LLC | 296,570 | 379,847 | +83,277 | 0.20 | 0.23 | +0.03 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,171,968 | 1,233,075 | +61,107 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 74,909 | 135,848 | +60,939 | 0.00 | 0.00 | +0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 685,025 | 744,298 | +59,273 | 0.03 | 0.03 | -0.01 | buy |
| ExodusPoint Capital Management, LP | 0 | 58,951 | +58,951 | 0.00 | 0.01 | +0.01 | buy |
| Capula Management Ltd | 0 | 55,709 | +55,709 | 0.00 | 0.01 | +0.01 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 13,576 | 64,809 | +51,233 | 0.00 | 0.01 | +0.01 | buy |
| HRT FINANCIAL LP | 0 | 46,579 | +46,579 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 44,529 | +44,529 | 0.00 | 0.02 | +0.02 | buy |
| XTX Topco Ltd | 0 | 38,761 | +38,761 | 0.00 | 0.05 | +0.05 | buy |
| Brevan Howard Capital Management LP | 0 | 30,963 | +30,963 | 0.00 | 0.03 | +0.03 | buy |
| Engineers Gate Manager LP | 0 | 28,992 | +28,992 | 0.00 | 0.01 | +0.01 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 26,677 | +26,677 | 0.00 | 0.08 | +0.08 | buy |
| Corton Capital Inc. | 0 | 24,221 | +24,221 | 0.00 | 0.19 | +0.19 | buy |
| Bayesian Capital Management, LP | 0 | 24,100 | +24,100 | 0.00 | 0.04 | +0.04 | buy |
| Teza Capital Management LLC | 0 | 23,705 | +23,705 | 0.00 | 0.04 | +0.04 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 23,608 | +23,608 | 0.00 | 0.00 | +0.00 | buy |
| NEOS Investment Management LLC | 11,477 | 34,606 | +23,129 | 0.01 | 0.02 | +0.01 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 0 | 21,847 | +21,847 | 0.00 | 0.01 | +0.01 | buy |
| DAFNA Capital Management LLC | 231,717 | 253,217 | +21,500 | 1.00 | 0.92 | -0.07 | buy |
| SHERBROOKE PARK ADVISERS LLC | 0 | 19,767 | +19,767 | 0.00 | 0.05 | +0.05 | buy |
| ALGERT GLOBAL LLC | 58,258 | 76,257 | +17,999 | 0.04 | 0.04 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 587 | 18,515 | +17,928 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 17,722 | +17,722 | 0.00 | 0.03 | +0.03 | buy |
| Bridgefront Capital, LLC | 0 | 16,721 | +16,721 | 0.00 | 0.11 | +0.11 | buy |
| Squarepoint Ops LLC | 0 | 16,700 | +16,700 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 493,276 | 507,443 | +14,167 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 57,898 | 70,917 | +13,019 | 0.00 | 0.00 | -0.00 | buy |
| Seelaus Asset Management LLC | 0 | 13,000 | +13,000 | 0.00 | 0.20 | +0.20 | buy |
| CANADA LIFE ASSURANCE Co | 46,426 | 58,852 | +12,426 | 0.00 | 0.00 | -0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 11,754 | +11,754 | 0.00 | 0.01 | +0.01 | buy |
| FIRST TRUST ADVISORS LP | 0 | 10,575 | +10,575 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 14,608 | 24,524 | +9,916 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 111,846 | 120,099 | +8,253 | 0.02 | 0.01 | -0.00 | buy |
| STRS OHIO | 0 | 6,900 | +6,900 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 64,090 | 70,948 | +6,858 | 0.01 | 0.01 | -0.00 | buy |
| Handelsbanken Fonder AB | 12,800 | 19,300 | +6,500 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 5,862 | +5,862 | 0.00 | 0.00 | +0.00 | buy |
| Aquatic Capital Management LLC | 0 | 5,800 | +5,800 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 5,461 | +5,461 | 0.00 | 0.01 | +0.01 | buy |
| EntryPoint Capital, LLC | 0 | 5,004 | +5,004 | 0.00 | 0.04 | +0.04 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 4,400 | +4,400 | 0.00 | 0.02 | +0.02 | buy |
| INNEALTA CAPITAL, LLC | 0 | 4,338 | +4,338 | 0.00 | 0.02 | +0.02 | buy |
| LPL Financial LLC | 10,063 | 13,198 | +3,135 | 0.00 | 0.00 | -0.00 | buy |
| Swiss National Bank | 95,396 | 98,296 | +2,900 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 28,134 | 31,004 | +2,870 | 0.00 | 0.00 | -0.00 | buy |
| JPMORGAN CHASE & CO | 40,226 | 42,568 | +2,342 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 27,735 | 29,858 | +2,123 | 0.00 | 0.00 | -0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 56,222 | 58,173 | +1,951 | 0.00 | 0.00 | -0.00 | buy |
| WINTON GROUP Ltd | 57,265 | 59,137 | +1,872 | 0.08 | 0.06 | -0.02 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 34,764 | 36,498 | +1,734 | 0.00 | 0.00 | -0.00 | buy |
| Diversified Trust Co | 12,078 | 13,545 | +1,467 | 0.01 | 0.01 | -0.00 | buy |
| US BANCORP \DE\ | 709 | 2,062 | +1,353 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 64,122 | 65,187 | +1,065 | 0.03 | 0.03 | -0.01 | buy |
| Caption Management, LLC | 5,000 | 6,000 | +1,000 | 0.01 | 0.01 | -0.00 | buy |
| Amundi | 9,566 | 10,392 | +826 | 0.00 | 0.00 | -0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 1,977 | 2,717 | +740 | 0.00 | 0.00 | +0.00 | buy |
| Louisiana State Employees Retirement System | 26,800 | 27,500 | +700 | 0.01 | 0.01 | -0.00 | buy |
| Arizona State Retirement System | 13,372 | 13,990 | +618 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 10 | 486 | +476 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 20,300 | 20,754 | +454 | 0.00 | 0.00 | -0.00 | buy |
| VIRTUS ADVISERS, LLC | 4,911 | 5,325 | +414 | 0.05 | 0.04 | -0.01 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 17,968 | 18,340 | +372 | 0.00 | 0.00 | -0.00 | buy |
| FIFTH THIRD BANCORP | 137 | 442 | +305 | 0.00 | 0.00 | +0.00 | buy |
| Blue Trust, Inc. | 0 | 285 | +285 | 0.00 | 0.00 | +0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 10,830 | 10,971 | +141 | 0.00 | 0.00 | -0.00 | buy |
| Versant Capital Management, Inc | 0 | 139 | +139 | 0.00 | 0.00 | +0.00 | buy |
| AXA S.A. | 232,072 | 232,200 | +128 | 0.01 | 0.01 | -0.00 | buy |
| Asset Dedication, LLC | 0 | 100 | +100 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 11,674 | 11,759 | +85 | 0.00 | 0.00 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 49,157 | 49,228 | +71 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 739 | 794 | +55 | 0.00 | 0.00 | -0.00 | buy |
| UMB Bank, n.a. | 22 | 69 | +47 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 355 | 379 | +24 | 0.00 | 0.00 | -0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 10 | 30 | +20 | 0.00 | 0.00 | +0.00 | buy |
| Parallel Advisors, LLC | 85,807 | 85,822 | +15 | 0.04 | 0.03 | -0.01 | buy |
| Smartleaf Asset Management LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| HUNTINGTON NATIONAL BANK | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |
| Covestor Ltd | 4 | 7 | +3 | 0.00 | 0.00 | 0.00 | buy |
| AlphaQuest LLC | 22 | 23 | +1 | 0.00 | 0.00 | -0.00 | buy |
| DiNuzzo Private Wealth, Inc. | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,242 | 5,242 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRAXIS INVESTMENT MANAGEMENT INC | 10,060 | 10,060 | 0 | 0.01 | 0.01 | -0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |