| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 17,056,878 | 16,826,695 | -230,183 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 1,119,240 | 10,126,897 | +9,007,657 | 0.00 | 0.00 | -0.00 | buy |
| ARCH Venture Management, LLC | 8,055,916 | 8,055,916 | 0 | 3.83 | 0.39 | -3.44 | hold |
| Octagon Capital Advisors LP | 13,915,371 | 7,750,000 | -6,165,371 | 5.40 | 0.28 | -5.12 | sell |
| Samsara BioCapital, LLC | 7,222,559 | 7,222,559 | 0 | 2.31 | 0.23 | -2.08 | hold |
| BALYASNY ASSET MANAGEMENT L.P. | 1,516,691 | 5,922,298 | +4,405,607 | 0.01 | 0.00 | -0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 4,416,903 | 5,277,904 | +861,001 | 0.02 | 0.00 | -0.02 | buy |
| Siren, L.L.C. | 5,208,968 | 5,208,968 | 0 | 0.48 | 0.05 | -0.43 | hold |
| 683 Capital Management, LLC | 5,190,800 | 5,000,000 | -190,800 | 1.34 | 0.15 | -1.19 | sell |
| HHLR ADVISORS, LTD. | 4,974,041 | 4,974,041 | 0 | 0.50 | 0.10 | -0.40 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 4,872,714 | 4,939,691 | +66,977 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 540,567 | 4,917,763 | +4,377,196 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 3,397,110 | 4,780,851 | +1,383,741 | 0.02 | 0.00 | -0.01 | buy |
| STATE STREET CORP | 9,310,969 | 4,388,109 | -4,922,860 | 0.00 | 0.00 | -0.00 | sell |
| Corient Private Wealth LLC | 3,845,885 | 3,985,383 | +139,498 | 0.02 | 0.00 | -0.01 | buy |
| Squarepoint Ops LLC | 221,591 | 3,398,757 | +3,177,166 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 51,860 | 3,254,233 | +3,202,373 | 0.01 | 0.07 | +0.05 | buy |
| BANK OF AMERICA CORP /DE/ | 1,906,669 | 3,173,725 | +1,267,056 | 0.00 | 0.00 | -0.00 | buy |
| BARCLAYS PLC | 576,533 | 3,065,806 | +2,489,273 | 0.00 | 0.00 | -0.00 | buy |
| Monashee Investment Management LLC | 0 | 2,167,000 | +2,167,000 | 0.72 | 0.46 | -0.26 | buy |
| Alyeska Investment Group, L.P. | 909,087 | 2,051,442 | +1,142,355 | 0.01 | 0.00 | -0.01 | buy |
| UBS Group AG | 1,771,381 | 1,883,583 | +112,202 | 0.00 | 0.00 | -0.00 | buy |
| Ensign Peak Advisors, Inc | 0 | 1,702,125 | +1,702,125 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 2,178,033 | 1,695,159 | -482,874 | 0.03 | 0.00 | -0.02 | sell |
| Rock Springs Capital Management LP | 3,266,960 | 1,609,492 | -1,657,468 | 0.52 | 0.03 | -0.49 | sell |
| MACKENZIE FINANCIAL CORP | 306,453 | 1,536,923 | +1,230,470 | 0.00 | 0.00 | -0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,685,778 | 1,510,076 | -175,702 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 1,416,540 | 1,408,960 | -7,580 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 1,284,335 | 1,305,886 | +21,551 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 658,888 | 1,217,868 | +558,980 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 1,792,114 | 1,180,544 | -611,570 | 0.00 | 0.00 | -0.00 | sell |
| NEA Management Company, LLC | 18,093,034 | 1,000,000 | -17,093,034 | 2.86 | 0.02 | -2.84 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 36,510 | 866,615 | +830,105 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 652,977 | 828,719 | +175,742 | 0.07 | 0.01 | -0.06 | buy |
| XTX Topco Ltd | 456,329 | 679,125 | +222,796 | 0.04 | 0.00 | -0.03 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 528,053 | 658,221 | +130,168 | 0.00 | 0.00 | -0.00 | buy |
| SMITH, MOORE & CO. | 280,000 | 470,000 | +190,000 | 0.07 | 0.01 | -0.05 | buy |
| PANAGORA ASSET MANAGEMENT INC | 147,296 | 469,946 | +322,650 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 478,909 | 464,968 | -13,941 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 447,901 | 428,241 | -19,660 | 0.00 | 0.00 | -0.00 | sell |
| Mariner, LLC | 64,450 | 418,404 | +353,954 | 0.00 | 0.00 | -0.00 | buy |
| IEQ CAPITAL, LLC | 11,211 | 393,739 | +382,528 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 198,709 | 389,431 | +190,722 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 33,957 | 319,995 | +286,038 | 0.00 | 0.00 | -0.00 | buy |
| ADAR1 Capital Management, LLC | 212,531 | 287,531 | +75,000 | 0.05 | 0.01 | -0.04 | buy |
| Virtu Financial LLC | 0 | 263,212 | +263,212 | 0.00 | 0.00 | +0.00 | buy |
| CHOREO, LLC | 75,111 | 250,111 | +175,000 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 214,869 | 216,396 | +1,527 | 0.00 | 0.00 | -0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 190,220 | 190,220 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MERCER GLOBAL ADVISORS INC /ADV | 23,983 | 189,328 | +165,345 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 3,584,288 | 187,418 | -3,396,870 | 0.01 | 0.00 | -0.01 | sell |
| Merit Financial Group, LLC | 155,178 | 154,441 | -737 | 0.00 | 0.00 | -0.00 | sell |
| Russell Investments Group, Ltd. | 171,071 | 145,272 | -25,799 | 0.00 | 0.00 | -0.00 | sell |
| Nuveen, LLC | 308,522 | 132,894 | -175,628 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 113,138 | 132,026 | +18,888 | 0.00 | 0.00 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 131,216 | +131,216 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 74,129 | 128,568 | +54,439 | 0.00 | 0.00 | -0.00 | buy |
| Creative Planning | 45,611 | 125,627 | +80,016 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 50,000 | 115,237 | +65,237 | 0.00 | 0.00 | -0.00 | buy |
| NINE MASTS CAPITAL Ltd | 0 | 114,766 | +114,766 | 0.00 | 0.01 | +0.01 | buy |
| HSBC HOLDINGS PLC | 0 | 113,943 | +113,943 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 78,756 | 109,978 | +31,222 | 0.00 | 0.00 | -0.00 | buy |
| Rockefeller Capital Management L.P. | 60,866 | 107,615 | +46,749 | 0.00 | 0.00 | -0.00 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 105,554 | 107,141 | +1,587 | 0.00 | 0.00 | -0.00 | buy |
| Cerity Partners LLC | 31,914 | 106,519 | +74,605 | 0.00 | 0.00 | -0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 23,964 | 103,443 | +79,479 | 0.00 | 0.00 | -0.00 | buy |
| Quarry LP | 0 | 100,000 | +100,000 | 0.00 | 0.01 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 89,489 | 95,606 | +6,117 | 0.00 | 0.00 | -0.00 | buy |
| Sivia Capital Partners, LLC | 35,042 | 91,679 | +56,637 | 0.02 | 0.01 | -0.02 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 107,467 | 91,418 | -16,049 | 0.00 | 0.00 | -0.00 | sell |
| Sequoia Financial Advisors, LLC | 88,467 | 90,570 | +2,103 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 83,595 | +83,595 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 73,896 | 75,746 | +1,850 | 0.06 | 0.01 | -0.06 | buy |
| Focus Partners Wealth | 0 | 73,013 | +73,013 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 75,375 | 71,282 | -4,093 | 0.01 | 0.00 | -0.01 | sell |
| Velan Capital Investment Management LP | 70,000 | 70,000 | 0 | 0.13 | 0.01 | -0.11 | hold |
| WADDELL & ASSOCIATES, LLC | 0 | 67,552 | +67,552 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 66,494 | 65,630 | -864 | 0.00 | 0.00 | -0.00 | sell |
| Chicago Partners Investment Group LLC | 0 | 62,489 | +62,489 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 58,441 | 57,923 | -518 | 0.00 | 0.00 | -0.00 | sell |
| CAPTRUST FINANCIAL ADVISORS | 0 | 57,504 | +57,504 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 37,615 | 55,925 | +18,310 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 85,582 | 54,002 | -31,580 | 0.00 | 0.00 | -0.00 | sell |
| AlphaCore Capital LLC | 26,377 | 53,011 | +26,634 | 0.00 | 0.00 | -0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 51,314 | 51,314 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 43,600 | 43,600 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cambridge Investment Research Advisors, Inc. | 76,940 | 42,800 | -34,140 | 0.00 | 0.00 | -0.00 | sell |
| China Universal Asset Management Co., Ltd. | 47,716 | 41,074 | -6,642 | 0.01 | 0.00 | -0.01 | sell |
| Skaana Management L.P. | 0 | 40,200 | +40,200 | 0.00 | 0.01 | +0.01 | buy |
| LETKO, BROSSEAU & ASSOCIATES INC | 39,400 | 39,400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ProShare Advisors LLC | 45,338 | 38,206 | -7,132 | 0.00 | 0.00 | -0.00 | sell |
| Curi Capital, LLC | 10,671 | 37,237 | +26,566 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 17,235 | 36,342 | +19,107 | 0.00 | 0.00 | -0.00 | buy |
| Vickerman Investment Advisors, Inc. | 34,787 | 34,787 | 0 | 0.02 | 0.00 | -0.02 | hold |
| Alpine Global Management, LLC | 0 | 32,827 | +32,827 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 228,896 | 31,520 | -197,376 | 0.00 | 0.00 | -0.00 | sell |
| Cetera Investment Advisers | 34,249 | 30,749 | -3,500 | 0.00 | 0.00 | -0.00 | sell |
| CSS LLC/IL | 0 | 30,000 | +30,000 | 0.00 | 0.00 | +0.00 | buy |
| Evernest Financial Advisors, LLC | 28,400 | 28,769 | +369 | 0.01 | 0.00 | -0.01 | buy |
| Kestra Advisory Services, LLC | 16,000 | 28,500 | +12,500 | 0.00 | 0.00 | -0.00 | buy |