| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 6,823,700 | 6,971,361 | +147,661 | 0.02 | 0.02 | +0.00 | buy |
| Rubric Capital Management LP | 3,750,000 | 3,999,800 | +249,800 | 2.21 | 2.35 | +0.13 | buy |
| BAKER BROS. ADVISORS LP | 2,826,246 | 2,834,643 | +8,397 | 0.78 | 0.91 | +0.13 | buy |
| BlackRock, Inc. | 486,737 | 2,739,615 | +2,252,878 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 2,259,889 | 2,259,889 | 0 | 5.53 | 6.56 | +1.04 | hold |
| MORGAN STANLEY | 997,786 | 1,011,143 | +13,357 | 0.00 | 0.00 | +0.00 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 892,666 | 957,514 | +64,848 | 0.02 | 0.03 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 811,922 | 874,786 | +62,864 | 0.01 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 27,656 | 772,806 | +745,150 | 0.00 | 0.00 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 611,398 | 718,199 | +106,801 | 0.22 | 0.27 | +0.05 | buy |
| STATE STREET CORP | 76,633 | 704,194 | +627,561 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 1,336,313 | 679,083 | -657,230 | 0.09 | 0.05 | -0.04 | sell |
| Point72 Asset Management, L.P. | 640,958 | 659,493 | +18,535 | 0.05 | 0.06 | +0.01 | buy |
| RICE HALL JAMES & ASSOCIATES, LLC | 608,416 | 624,928 | +16,512 | 1.63 | 1.95 | +0.31 | buy |
| Pictet Asset Management Holding SA | 623,288 | 608,650 | -14,638 | 0.03 | 0.04 | +0.01 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 44,320 | 604,180 | +559,860 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 649,629 | 572,598 | -77,031 | 0.07 | 0.07 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 959,257 | 569,756 | -389,501 | 0.04 | 0.02 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 420,914 | 561,480 | +140,566 | 0.02 | 0.03 | +0.01 | buy |
| ALLIANCEBERNSTEIN L.P. | 598,888 | 556,151 | -42,737 | 0.01 | 0.01 | +0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 480,175 | 504,853 | +24,678 | 0.01 | 0.02 | +0.00 | buy |
| SG Americas Securities, LLC | 640,179 | 504,001 | -136,178 | 0.03 | 0.02 | -0.02 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 647,731 | 437,192 | -210,539 | 0.02 | 0.01 | -0.01 | sell |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 438,002 | 431,324 | -6,678 | 0.01 | 0.01 | +0.00 | sell |
| ORBIMED ADVISORS LLC | 180,599 | 420,600 | +240,001 | 0.19 | 0.51 | +0.32 | buy |
| BANK OF AMERICA CORP /DE/ | 735,940 | 413,411 | -322,529 | 0.00 | 0.00 | -0.00 | sell |
| OBERWEIS ASSET MANAGEMENT INC/ | 318,634 | 413,034 | +94,400 | 0.45 | 0.55 | +0.09 | buy |
| Aberdeen Group plc | 373,634 | 403,485 | +29,851 | 0.03 | 0.04 | +0.01 | buy |
| Fisher Asset Management, LLC | 428,972 | 398,266 | -30,706 | 0.01 | 0.01 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 523,691 | 387,606 | -136,085 | 0.01 | 0.01 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 378,697 | 375,039 | -3,658 | 0.01 | 0.01 | +0.00 | sell |
| Penn Capital Management Company, LLC | 301,993 | 368,114 | +66,121 | 1.13 | 1.49 | +0.37 | buy |
| NORTHERN TRUST CORP | 36,924 | 315,246 | +278,322 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 499,792 | 309,682 | -190,110 | 0.05 | 0.04 | -0.01 | sell |
| Qube Research & Technologies Ltd | 686,853 | 304,080 | -382,773 | 0.05 | 0.02 | -0.03 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 209,617 | 272,579 | +62,962 | 0.01 | 0.02 | +0.01 | buy |
| NOMURA HOLDINGS INC | 342,939 | 270,724 | -72,215 | 0.14 | 0.07 | -0.06 | sell |
| Soleus Capital Management, L.P. | 521,353 | 246,353 | -275,000 | 1.02 | 0.54 | -0.47 | sell |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 249,278 | 241,382 | -7,896 | 1.90 | 2.02 | +0.12 | sell |
| Bank of New York Mellon Corp | 17,388 | 232,531 | +215,143 | 0.00 | 0.00 | +0.00 | buy |
| ArrowMark Colorado Holdings LLC | 316,956 | 215,546 | -101,410 | 0.41 | 0.57 | +0.17 | sell |
| STEMPOINT CAPITAL LP | 0 | 209,234 | +209,234 | 0.00 | 2.32 | +2.32 | buy |
| GOLDMAN SACHS GROUP INC | 174,901 | 191,364 | +16,463 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 284,005 | 188,565 | -95,440 | 0.01 | 0.01 | -0.00 | sell |
| BRAIDWELL LP | 272,522 | 183,822 | -88,700 | 0.44 | 0.43 | -0.00 | sell |
| CASTLEARK MANAGEMENT LLC | 181,512 | 174,032 | -7,480 | 0.29 | 0.30 | +0.01 | sell |
| Rockefeller Capital Management L.P. | 173,438 | 173,438 | 0 | 0.01 | 0.02 | +0.00 | hold |
| PEREGRINE CAPITAL MANAGEMENT LLC | 181,360 | 161,464 | -19,896 | 0.32 | 0.34 | +0.01 | sell |
| Granahan Investment Management, LLC | 209,256 | 151,725 | -57,531 | 0.49 | 0.35 | -0.14 | sell |
| Squarepoint Ops LLC | 158,093 | 140,059 | -18,034 | 0.02 | 0.02 | +0.00 | sell |
| Nuveen, LLC | 26,948 | 117,989 | +91,041 | 0.00 | 0.00 | +0.00 | buy |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 114,289 | 109,359 | -4,930 | 0.04 | 0.05 | +0.01 | sell |
| NORDEA INVESTMENT MANAGEMENT AB | 106,635 | 107,157 | +522 | 0.00 | 0.01 | +0.00 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 101,575 | +101,575 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 50,299 | 101,575 | +51,276 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 104,654 | 99,852 | -4,802 | 0.01 | 0.01 | +0.00 | sell |
| GLOBEFLEX CAPITAL L P | 93,396 | 93,396 | 0 | 0.68 | 0.76 | +0.08 | hold |
| MILLENNIUM MANAGEMENT LLC | 564,420 | 93,364 | -471,056 | 0.02 | 0.00 | -0.02 | sell |
| Lisanti Capital Growth, LLC | 31,065 | 87,305 | +56,240 | 0.38 | 1.23 | +0.85 | buy |
| Swiss National Bank | 71,500 | 73,700 | +2,200 | 0.00 | 0.00 | +0.00 | buy |
| SEGALL BRYANT & HAMILL, LLC | 0 | 71,901 | +71,901 | 0.00 | 0.05 | +0.05 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 68,077 | +68,077 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 63,346 | 67,715 | +4,369 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 21,432 | 67,291 | +45,859 | 0.00 | 0.01 | +0.00 | buy |
| Allspring Global Investments Holdings, LLC | 15,356 | 65,097 | +49,741 | 0.00 | 0.01 | +0.01 | buy |
| RHUMBLINE ADVISERS | 7,286 | 58,529 | +51,243 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 7,302 | 56,408 | +49,106 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 56,494 | 55,765 | -729 | 0.31 | 0.32 | +0.00 | sell |
| Linden Thomas Advisory Services, LLC | 121,777 | 54,803 | -66,974 | 0.56 | 0.28 | -0.28 | sell |
| Trexquant Investment LP | 135,280 | 53,507 | -81,773 | 0.05 | 0.02 | -0.03 | sell |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 88,600 | 52,700 | -35,900 | 0.01 | 0.00 | -0.00 | sell |
| TRUIST FINANCIAL CORP | 0 | 51,671 | +51,671 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 16,229 | 50,786 | +34,557 | 0.00 | 0.01 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 8,368 | 48,677 | +40,309 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 69,700 | 45,174 | -24,526 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 41,975 | 42,559 | +584 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 474,750 | 41,665 | -433,085 | 0.02 | 0.00 | -0.01 | sell |
| Aquatic Capital Management LLC | 4,369 | 41,528 | +37,159 | 0.01 | 0.09 | +0.09 | buy |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 0 | 41,504 | +41,504 | 0.00 | 0.03 | +0.03 | buy |
| PDT Partners, LLC | 80,263 | 40,567 | -39,696 | 0.23 | 0.14 | -0.09 | sell |
| Man Group plc | 127,186 | 40,524 | -86,662 | 0.01 | 0.00 | -0.01 | sell |
| CITIGROUP INC | 33,714 | 40,513 | +6,799 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 43,712 | 40,488 | -3,224 | 0.00 | 0.00 | +0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 31,089 | 38,148 | +7,059 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 24,602 | 35,549 | +10,947 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 34,830 | +34,830 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 52,303 | 33,017 | -19,286 | 0.03 | 0.02 | -0.01 | sell |
| Voleon Capital Management LP | 120,385 | 32,806 | -87,579 | 0.12 | 0.04 | -0.09 | sell |
| AMERIPRISE FINANCIAL INC | 31,755 | 32,571 | +816 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 20,925 | 32,420 | +11,495 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 107,017 | 31,553 | -75,464 | 0.00 | 0.00 | -0.00 | sell |
| Financial Enhancement Group LLC | 0 | 31,391 | +31,391 | 0.00 | 0.24 | +0.24 | buy |
| Baird Financial Group, Inc. | 40,249 | 30,708 | -9,541 | 0.00 | 0.00 | -0.00 | sell |
| Penserra Capital Management LLC | 53,102 | 30,226 | -22,876 | 0.03 | 0.01 | -0.02 | sell |
| STATE OF WISCONSIN INVESTMENT BOARD | 17,076 | 29,876 | +12,800 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 42,950 | 29,746 | -13,204 | 0.01 | 0.01 | -0.00 | sell |
| Artia Global Partners LP | 29,200 | 29,200 | 0 | 0.32 | 0.35 | +0.04 | hold |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 28,955 | 28,955 | 0 | 0.00 | 0.01 | +0.00 | hold |
| ADAR1 Capital Management, LLC | 26,913 | 26,913 | 0 | 0.08 | 0.08 | +0.00 | hold |
| Caption Management, LLC | 0 | 25,000 | +25,000 | 0.00 | 0.06 | +0.06 | buy |