| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 0 | 3,298,256 | +3,298,256 | 0.00 | 0.00 | +0.00 | buy |
| BRAIDWELL LP | 2,058,303 | 2,894,513 | +836,210 | 1.21 | 2.05 | +0.84 | buy |
| FMR LLC | 1,882 | 696,810 | +694,928 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 508,373 | +508,373 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 388,356 | +388,356 | 0.00 | 0.02 | +0.02 | buy |
| ADAR1 Capital Management, LLC | 114,309 | 436,668 | +322,359 | 0.43 | 1.83 | +1.40 | buy |
| JANE STREET GROUP, LLC | 29,636 | 345,092 | +315,456 | 0.00 | 0.01 | +0.01 | buy |
| OBERWEIS ASSET MANAGEMENT INC/ | 0 | 201,000 | +201,000 | 0.00 | 0.26 | +0.26 | buy |
| JPMORGAN CHASE & CO | 0 | 199,973 | +199,973 | 0.00 | 0.00 | +0.00 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 0 | 186,626 | +186,626 | 0.00 | 0.01 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 175,321 | +175,321 | 0.00 | 0.00 | +0.00 | buy |
| CASTLEARK MANAGEMENT LLC | 0 | 167,200 | +167,200 | 0.00 | 0.17 | +0.17 | buy |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 25,786 | 189,986 | +164,200 | 0.00 | 0.02 | +0.02 | buy |
| D. E. Shaw & Co., Inc. | 169,648 | 320,997 | +151,349 | 0.00 | 0.01 | +0.01 | buy |
| CITADEL ADVISORS LLC | 54,820 | 198,413 | +143,593 | 0.00 | 0.01 | +0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 615,836 | 730,943 | +115,107 | 0.11 | 0.16 | +0.05 | buy |
| Parkman Healthcare Partners LLC | 647,142 | 755,244 | +108,102 | 1.65 | 2.41 | +0.76 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 87,002 | 192,926 | +105,924 | 0.00 | 0.00 | +0.00 | buy |
| Soleus Capital Management, L.P. | 200,000 | 302,500 | +102,500 | 0.33 | 0.63 | +0.30 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 231,079 | 324,064 | +92,985 | 0.02 | 0.04 | +0.02 | buy |
| MARSHALL WACE, LLP | 0 | 90,571 | +90,571 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 0 | 80,600 | +80,600 | 0.00 | 0.03 | +0.03 | buy |
| DEUTSCHE BANK AG\ | 0 | 80,314 | +80,314 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 664,040 | 742,307 | +78,267 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 18,603 | 91,159 | +72,556 | 0.01 | 0.06 | +0.05 | buy |
| BARCLAYS PLC | 0 | 64,629 | +64,629 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 125,995 | 184,169 | +58,174 | 0.00 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,610 | 66,567 | +55,957 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 0 | 55,488 | +55,488 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 0 | 49,507 | +49,507 | 0.00 | 0.00 | +0.00 | buy |
| RICE HALL JAMES & ASSOCIATES, LLC | 600,630 | 649,630 | +49,000 | 0.67 | 0.88 | +0.21 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 57,230 | 106,219 | +48,989 | 0.00 | 0.01 | +0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 47,717 | +47,717 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 44,229 | +44,229 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 0 | 39,560 | +39,560 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 0 | 37,242 | +37,242 | 0.00 | 0.08 | +0.08 | buy |
| Jump Financial, LLC | 11,163 | 45,607 | +34,444 | 0.00 | 0.02 | +0.02 | buy |
| Woodline Partners LP | 0 | 34,029 | +34,029 | 0.00 | 0.01 | +0.01 | buy |
| Cerity Partners LLC | 0 | 33,384 | +33,384 | 0.00 | 0.00 | +0.00 | buy |
| SEGALL BRYANT & HAMILL, LLC | 0 | 27,026 | +27,026 | 0.00 | 0.01 | +0.01 | buy |
| Verition Fund Management LLC | 0 | 26,784 | +26,784 | 0.00 | 0.00 | +0.00 | buy |
| Nebula Research & Development LLC | 15,070 | 39,004 | +23,934 | 0.05 | 0.12 | +0.07 | buy |
| CITIGROUP INC | 7,894 | 31,696 | +23,802 | 0.00 | 0.00 | +0.00 | buy |
| Semanteon Capital Management, LP | 0 | 22,057 | +22,057 | 0.00 | 0.38 | +0.38 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 140,061 | 161,643 | +21,582 | 0.00 | 0.00 | +0.00 | buy |
| GLOBEFLEX CAPITAL L P | 6,790 | 27,940 | +21,150 | 0.01 | 0.07 | +0.05 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 79,200 | 100,001 | +20,801 | 0.01 | 0.01 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 20,235 | +20,235 | 0.00 | 0.01 | +0.01 | buy |
| Paloma Partners Management Co | 0 | 19,300 | +19,300 | 0.00 | 0.03 | +0.03 | buy |
| Jackson Creek Investment Advisors LLC | 54,296 | 70,296 | +16,000 | 0.37 | 0.52 | +0.15 | buy |
| Corton Capital Inc. | 0 | 15,146 | +15,146 | 0.00 | 0.18 | +0.18 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 14,175 | +14,175 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 181,966 | 195,852 | +13,886 | 0.17 | 0.23 | +0.05 | buy |
| HSBC HOLDINGS PLC | 0 | 13,666 | +13,666 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 29,226 | 41,870 | +12,644 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 9,482 | 21,721 | +12,239 | 0.00 | 0.00 | +0.00 | buy |
| BOSUN ASSET MANAGEMENT, LLC | 21,875 | 33,824 | +11,949 | 0.24 | 0.41 | +0.16 | buy |
| ExodusPoint Capital Management, LP | 0 | 11,938 | +11,938 | 0.00 | 0.00 | +0.00 | buy |
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 11,015 | +11,015 | 0.00 | 0.05 | +0.05 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 10,729 | +10,729 | 0.00 | 0.02 | +0.02 | buy |
| XTX Topco Ltd | 16,828 | 27,302 | +10,474 | 0.03 | 0.05 | +0.02 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 0 | 10,143 | +10,143 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 9,723 | +9,723 | 0.00 | 0.05 | +0.05 | buy |
| HRT FINANCIAL LP | 11,075 | 20,691 | +9,616 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 9,561 | +9,561 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 0 | 9,450 | +9,450 | 0.00 | 0.00 | +0.00 | buy |
| Cornerstone Investment Partners, LLC | 0 | 9,319 | +9,319 | 0.00 | 0.01 | +0.01 | buy |
| Atria Wealth Solutions, Inc. | 0 | 9,230 | +9,230 | 0.00 | 0.00 | +0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 0 | 9,127 | +9,127 | 0.00 | 0.00 | +0.00 | buy |
| Allianz Asset Management GmbH | 0 | 8,800 | +8,800 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 8,025 | +8,025 | 0.00 | 0.00 | +0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0 | 7,553 | +7,553 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 38,976 | 44,538 | +5,562 | 0.00 | 0.00 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 0 | 4,600 | +4,600 | 0.00 | 0.03 | +0.03 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 12,774 | 17,118 | +4,344 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 16,270 | 20,461 | +4,191 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 3,908 | +3,908 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 56,066 | 59,864 | +3,798 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 3,649 | +3,649 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 625,309 | 628,609 | +3,300 | 1.19 | 1.12 | -0.07 | buy |
| nVerses Capital, LLC | 0 | 3,200 | +3,200 | 0.00 | 0.04 | +0.04 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 45,377 | 48,460 | +3,083 | 0.02 | 0.03 | +0.01 | buy |
| China Universal Asset Management Co., Ltd. | 4,734 | 7,810 | +3,076 | 0.01 | 0.02 | +0.01 | buy |
| Sound View Wealth Advisors Group, LLC | 10,642 | 13,666 | +3,024 | 0.02 | 0.03 | +0.01 | buy |
| CWM, LLC | 0 | 2,449 | +2,449 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 2,000 | +2,000 | 0.00 | 0.02 | +0.02 | buy |
| Legal & General Group Plc | 43,902 | 45,404 | +1,502 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 12,168 | 13,568 | +1,400 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 66,433 | 67,533 | +1,100 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 88,391 | 89,300 | +909 | 0.01 | 0.02 | +0.01 | buy |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 199,799 | 200,516 | +717 | 0.70 | 0.87 | +0.18 | buy |
| ROYAL BANK OF CANADA | 4,620 | 5,171 | +551 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 0 | 539 | +539 | 0.00 | 0.00 | +0.00 | buy |
| PEREGRINE CAPITAL MANAGEMENT LLC | 239,156 | 239,682 | +526 | 0.13 | 0.18 | +0.05 | buy |
| MACQUARIE GROUP LTD | 0 | 500 | +500 | 0.00 | 0.00 | +0.00 | buy |
| Arizona State Retirement System | 11,192 | 11,648 | +456 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 11,882 | 12,230 | +348 | 0.00 | 0.00 | +0.00 | buy |
| BROWN BROTHERS HARRIMAN & CO | 0 | 333 | +333 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,203 | 1,469 | +266 | 0.00 | 0.00 | +0.00 | buy |
| Planned Solutions, Inc. | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |